{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T08:49:01Z","timestamp":1789202941189,"version":"build-2803163510"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Patients with acute myocardial infarction (MI) with bundle branch block (BBB) have a poor prognosis, but distinction between left (L)- and right (R)-sided BBB is seldom made in epidemiological studies. We studied long-term mortality associated with RBBB and LBBB in the TRAndolapril Cardiac Evaluation (TRACE) study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>TRACE screened consecutive patients presenting with an MI and recorded clinical, electro- and echo-cardiographic variables. Subsequently, deaths were recorded during a minimum follow-up of 15 years. In total, 6676 consecutive patients with MI were hospitalized at 27 centres in Denmark. Of these, 533 (8%) had BBB, of whom 260 (4%) had RBBB and 273 (4%) had LBBB. Overall, 5196 (78%) patients died, 256 (94%) with LBBB and 235 (90%) with RBBB compared with 4705 (77%) of those without BBB (P &amp;lt; 0.001). In multivariable analyses, hazard ratios (HRs) of RBBB and LBBB were 1.23 [95% confidence interval (CI), 1.07\u20131.42] and 1.05 (95% CI, 0.91\u20131.20), respectively. There was interaction between each type of BBB and left ventricular (LV) systolic function (P = 0.02). Right BBB was associated with a worse prognosis in patients with reduced LV systolic function [HR = 1.31 with wall motion index (WMI) \u2264 1.5 (95% CI, 1.11\u20131.55] while LBBB had a poor prognosis in patients with preserved LV systolic (HR if WMI &amp;gt; 1.5, 1.70; 95% CI, 1.12\u20132.57).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Right BBB was a predictor of increased mortality in patients with reduced LV systolic function, whereas LBBB was a marker of increased mortality in patients with preserved LV systolic function.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/eurjhf\/hfr130","type":"journal-article","created":{"date-parts":[[2011,10,25]],"date-time":"2011-10-25T20:54:20Z","timestamp":1319576060000},"page":"1349-1354","source":"Crossref","is-referenced-by-count":38,"title":["Right and Left Bundle Branch Block as Predictors of Long-Term Mortality Following Myocardial Infarction"],"prefix":"10.1093","volume":"13","author":[{"given":"Christian","family":"Lewinter","sequence":"first","affiliation":[{"name":"Academic Cardiology, Castle Hill Hospital, Hull York Medical School (HYMS) , Hull ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Torp-Pedersen","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Gentofte Hospital, University of Copenhagen , Copenhagen ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John G.F.","family":"Cleland","sequence":"additional","affiliation":[{"name":"Academic Cardiology, Castle Hill Hospital, Hull York Medical School (HYMS) , Hull ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"K\u00f8ber","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rigshospitalet, University of Copenhagen , Blegdamsvej 9, 2100, K\u00f8benhavn ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,2,18]]},"reference":[{"key":"2026020203272138400_ejhfhfr130-bib-0001","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0002-9149(01)01626-5","article-title":"Bundle branch block as a predictor of long-term survival after acute myocardial infarction","volume":"88","author":"Brilakis","year":"2001","journal-title":"Am J Cardiol"},{"key":"2026020203272138400_ejhfhfr130-bib-0002","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1016\/0002-9149(91)90882-L","article-title":"Influence of right bundle branch block on short- and long-term survival after inferior wall Q-wave myocardial infarction","volume":"67","author":"Ricou","year":"1991","journal-title":"Am J Cardiol"},{"key":"2026020203272138400_ejhfhfr130-bib-0003","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.1161\/01.CIR.0000143136.51424.38","article-title":"Comorbidity and myocardial dysfunction are the main explanations for the higher 1-year mortality in acute myocardial infarction with left bundle-branch block","volume":"110","author":"Stenestrand","year":"2004","journal-title":"Circulation"},{"key":"2026020203272138400_ejhfhfr130-bib-0004","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1056\/NEJMoa050496","article-title":"The effect of cardiac resynchronization on morbidity and mortality in heart failure","volume":"352","author":"Cleland","year":"2005","journal-title":"N Engl J Med"},{"key":"2026020203272138400_ejhfhfr130-bib-0005","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1093\/eurjhf\/hfq192","article-title":"2010 focused update of ESC Guidelines on device therapy in heart failure: an update of the 2008 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure and the 2007 ESC Guidelines for cardiac and resynchronization therapy. 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