{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T15:58:05Z","timestamp":1792166285858,"version":"4.4.0"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Registries and surveys improve knowledge of the \u2018real world\u2019. This paper aims to describe baseline clinical profiles, management strategies, and the in-hospital outcome of patients admitted to hospital for an acute heart failure (AHF) episode.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>IN-HF Outcome is a nationwide, prospective, multicentre, observational study conducted in 61 Cardiology Centres in Italy. Up to December 2009, 5610 patients had been enrolled, 1855 (33%) with AHF and 3755 (67%) with chronic heart failure (CHF). Baseline and in-hospital outcome data of AHF patients are presented. Mean age was 72 \u00b1 12 years, and 39.8% were female. Hospital admission was due to new-onset heart failure (HF) in 43% of cases. Co-morbid conditions were observed more frequently in the worsening HF group, while those with de novo HF showed a higher heart rate, blood pressure, and more preserved left ventricular ejection fraction (LVEF). Electrical devices were previously implanted in 13.3% of the entire group. Inotropes were administered in 19.4% of the patients. The median duration of hospital stay was 10 days (interquartile range 7\u201315). All-cause in-hospital death was 6.4%, similar in worsening and de novo HF. Older age, hypotension, cardiogenic shock, pulmonary oedema, symptoms of hypoperfusion, hyponatraemia, and elevated creatinine were independent predictors of all-cause death.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our registry confirms that in-hospital mortality in AHF is still high, with a long length of stay. Pharmacological treatment seems to be practically unchanged in the last decades, and the adherence to HF guidelines concerning implantable cardioverter defibrillators\/cardiac resynchronization therapy is still very low. Some AHF phenotypes are characterized by worst prognosis and need specific research projects.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/eurjhf\/hfs117","type":"journal-article","created":{"date-parts":[[2012,7,25]],"date-time":"2012-07-25T22:03:22Z","timestamp":1343253802000},"page":"1208-1217","source":"Crossref","is-referenced-by-count":115,"title":["Acute Heart Failure Patient Profiles, Management and In-Hospital Outcome: Results of the Italian Registry on Heart Failure Outcome"],"prefix":"10.1093","volume":"14","author":[{"given":"Fabrizio","family":"Oliva","sequence":"first","affiliation":[{"name":"Cardiologia 2 Heart Failure and Heart Transplant Program, \u2018A. De Gasperis\u2019 Cardiovascular Department, Niguarda Hospital , Milano ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Mortara","sequence":"additional","affiliation":[{"name":"Department of Clinical Cardiology and Heart Failure, Policlinico di Monza , Monza ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Cacciatore","sequence":"additional","affiliation":[{"name":"San Giovanni-Addolorata Hospital, Department of Cardiology , Roma ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Chinaglia","sequence":"additional","affiliation":[{"name":"Maria Vittoria Hospital, Cardiology Department , Torino ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Di Lenarda","sequence":"additional","affiliation":[{"name":"Cardiovascular Unit, Azienda Servizi Sanitari n. 1 Triestina , Trieste ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Gorini","sequence":"additional","affiliation":[{"name":"NMCO Research Center , Firenze ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Metra","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Spedali Civili , Brescia ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Senni","sequence":"additional","affiliation":[{"name":"USC Cardiovascular Medicine, Ospedali Riuniti , Bergamo ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aldo P.","family":"Maggioni","sequence":"additional","affiliation":[{"name":"NMCO Research Center , Firenze ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Tavazzi","sequence":"additional","affiliation":[{"name":"GVM Hospitals of Care and Research, Ettore Sansavini Health Science Foundation , Cotignola ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,2,18]]},"reference":[{"key":"2026011921165488700_ejhfhfs117-bib-0001","doi-asserted-by":"crossref","first-page":"e69","DOI":"10.1161\/CIRCULATIONAHA.106.179918","article-title":"update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee 2007","volume":"115","author":"Rosamond","year":"2007","journal-title":"Circulation"},{"key":"2026011921165488700_ejhfhfs117-bib-0002","doi-asserted-by":"crossref","first-page":"3958","DOI":"10.1161\/CIRCULATIONAHA.105.590091","article-title":"Acute heart failure syndromes: current state and framework for future research","volume":"112","author":"Gheorghiade","year":"2005","journal-title":"Circulation"},{"key":"2026011921165488700_ejhfhfs117-bib-0003","article-title":"ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. 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