{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T01:27:08Z","timestamp":1790386028717,"version":"4.1.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The burden of heart failure (HF)-related hospitalization and mortality of female patients with HF is substantial. Currently, several gender-specific distinctions have been recognized amongst HF patients, but their relationships to outcomes have not been fully elucidated. Accordingly, in the current work, we aimed to explore gender-specific clinical and echocardiographic measures and to assess their potential impact on outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>We studied all consecutive HF patients, aged 50 or older, who had been hospitalized between January 2000 and December 2009, and had undergone at least one echocardiography study. A comparative analysis of clinical and echocardiographic findings was performed between 5228 males and 4107 females. Patients were followed for a mean of 2.8 \u00b1 2.6 years. Females compared with males had less ischaemic heart disease, prior stroke, chronic renal failure, and COPD, and higher rates of hypertension, AF, obesity, valvular abnormalities, and pulmonary hypertension. Unadjusted 30-day and 1-year mortality rates were higher among women, while age-adjusted rates were similar. Predictors of outcomes varied between genders. Female-specific predictors of mortality included aortic stenosis, pulmonary hypertension, and malignancy, whereas diastolic dysfunction and chronic renal failure were found to be male-specific predictors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Age-adjusted mortality rates of male and female hospitalized HF patients are similarly high. Predictors of mortality, however, are gender distinctive, and these measures may allow a better identification of high-risk HF patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/eurjhf\/hft024","type":"journal-article","created":{"date-parts":[[2013,2,19]],"date-time":"2013-02-19T07:45:17Z","timestamp":1361259917000},"page":"734-741","source":"Crossref","is-referenced-by-count":28,"title":["Gender-Related Differences in Hospitalized Heart Failure Patients"],"prefix":"10.1093","volume":"15","author":[{"given":"Gideon Y.","family":"Stein","sequence":"first","affiliation":[{"name":"Department of Internal Medicine \u2018B\u2019, Beilinson Hospital, Rabin Medical Center, Petah Tikva and Sackler Faculty of Medicine, Tel Aviv \u00a0","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuvia","family":"Ben-Gal","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beilinson Hospital, Rabin Medical Center, Petah Tikva and Sackler Faculty of Medicine, Tel Aviv \u00a0","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelika","family":"Kremer","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beilinson Hospital, Rabin Medical Center, Petah Tikva and Sackler Faculty of Medicine, Tel Aviv \u00a0","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamir","family":"Bental","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beilinson Hospital, Rabin Medical Center, Petah Tikva and Sackler Faculty of Medicine, Tel Aviv \u00a0","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danny","family":"Alon","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine \u2018B\u2019, Beilinson Hospital, Rabin Medical Center, Petah Tikva and Sackler Faculty of Medicine, Tel Aviv \u00a0","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roman","family":"Korenfeld","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine \u2018B\u2019, Beilinson Hospital, Rabin Medical Center, Petah Tikva and Sackler Faculty of Medicine, Tel Aviv \u00a0","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Idit","family":"Yedidia","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beilinson Hospital, Rabin Medical Center, Petah Tikva and Sackler Faculty of Medicine, Tel Aviv \u00a0","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avital","family":"Porter","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beilinson Hospital, Rabin Medical Center, Petah Tikva and Sackler Faculty of Medicine, Tel Aviv \u00a0","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evgeny","family":"Abramson","sequence":"additional","affiliation":[{"name":"Epidemiology & Informatics Unit, Beilinson Hospital, Rabin Medical Center , Petah Tikva ,","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Sagie","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine \u2018B\u2019, Hasharon Hospital, Tel Aviv \u00a0","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shmuel","family":"Fuchs","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine \u2018B\u2019, Beilinson Hospital, Rabin Medical Center, Petah Tikva and Sackler Faculty of Medicine, Tel Aviv \u00a0","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,1,27]]},"reference":[{"key":"2026011921151609100_ejhfhft024-bib-0001","first-page":"e2","article-title":"Heart disease and stroke statistics\u20142012 update: a report from the American Heart Association","volume":"125","author":"Roger","year":"2012","journal-title":"Circulation"},{"key":"2026011921151609100_ejhfhft024-bib-0002","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1093\/eurjhf\/hfr170","article-title":"Ten-year prognosis of heart failure in the community: follow-up data from the Echocardiographic Heart of England Screening (ECHOES) study","volume":"14","author":"Taylor","year":"2012","journal-title":"Eur J Heart Fail"},{"key":"2026011921151609100_ejhfhft024-bib-0003","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.ahj.2010.05.007","article-title":"Predictors of early readmission or death in elderly patients with 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Results from EuroHeart Failure Survey II","volume":"10","author":"Nieminen","year":"2008","journal-title":"Eur J Heart Fail"},{"key":"2026011921151609100_ejhfhft024-bib-0006","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.1093\/eurheartj\/ehr254","article-title":"The survival of patients with heart failure with preserved or reduced left ventricular ejection fraction: an individual patient data meta-analysis","volume":"33","author":"Meta-analysis Global Group in Chronic Heart Failure (MAGGIC)","year":"2012","journal-title":"Eur Heart J"},{"key":"2026011921151609100_ejhfhft024-bib-0007","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1093\/eurjhf\/hfs105","article-title":"ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC","volume":"14","author":"McMurray","year":"2012","journal-title":"Eur J Heart Fail"},{"key":"2026011921151609100_ejhfhft024-bib-0008","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1093\/eurheartj\/ehq094","article-title":"Women and research on cardiovascular diseases in Europe: a report from the European Heart Health Strategy (EuroHeart) project","volume":"31","author":"Stramba-Badiale","year":"2010","journal-title":"Eur Heart J"},{"key":"2026011921151609100_ejhfhft024-bib-0009","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1093\/eurheartj\/ehr048","article-title":"Red alert for women\u2019s heart: the urgent need for more research and knowledge on cardiovascular disease in women: proceedings of the workshop held in Brussels on gender differences in cardiovascular disease, 29 September 2010","volume":"32","author":"Maas","year":"2011","journal-title":"Eur Heart J"},{"key":"2026011921151609100_ejhfhft024-bib-0010","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1080\/028134301300034549","article-title":"Patients in primary health care diagnosed and treated as heart failure, with special reference to gender differences","volume":"19","author":"Agvall","year":"2001","journal-title":"Scand J Prim Health Care"},{"key":"2026011921151609100_ejhfhft024-bib-0011","doi-asserted-by":"crossref","first-page":"473","DOI":"10.2217\/WHE.12.22","article-title":"Disparities in heart failure and other cardiovascular diseases among women","volume":"8","author":"McSweeney","year":"2012","journal-title":"Womens Health (Lond Engl)"},{"key":"2026011921151609100_ejhfhft024-bib-0012","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1093\/eurjhf\/hfn041","article-title":"Influence of gender of physicians and patients on guideline-recommended treatment of chronic heart failure in a cross-sectional study","volume":"11","author":"Baumhakel","year":"2009","journal-title":"Eur J Heart Fail"},{"key":"2026011921151609100_ejhfhft024-bib-0013","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S1388-9842(99)00053-7","article-title":"Diagnostic tests, treatment, follow-up in heart failure patients\u2014is there a gender bias in the coherence to guidelines?","volume":"1","author":"Mejhert","year":"1999","journal-title":"Eur J Heart Fail"},{"key":"2026011921151609100_ejhfhft024-bib-0014","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.euje.2005.12.014","article-title":"Recommendations for chamber quantification","volume":"7","author":"Lang","year":"2006","journal-title":"Eur J Echocardiogr"},{"key":"2026011921151609100_ejhfhft024-bib-0015","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.ahj.2010.06.040","article-title":"Diastolic dysfunction: improved understanding using emerging imaging techniques","volume":"160","author":"Daneshvar","year":"2010","journal-title":"Am Heart J"},{"key":"2026011921151609100_ejhfhft024-bib-0016","doi-asserted-by":"crossref","DOI":"10.1136\/hrt.2006.099523","article-title":"Management of patients with heart failure in clinical practice: differences between men and women","volume":"94","author":"Lenzen","year":"2008","journal-title":"Heart"},{"key":"2026011921151609100_ejhfhft024-bib-0017","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.amjcard.2011.09.026","article-title":"Comparison of women versus men hospitalized with heart failure (from a 20-year registry in a Middle-Eastern country 1991\u20132010)","volume":"109","author":"Al Suwaidi","year":"2011","journal-title":"Am J Cardiol"},{"key":"2026011921151609100_ejhfhft024-bib-0018","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1016\/j.jacc.2006.11.041","article-title":"Associations of gender and etiology with outcomes in heart failure with systolic dysfunction: a pooled analysis of 5 randomized control trials","volume":"49","author":"Frazier","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"2026011921151609100_ejhfhft024-bib-0019","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1093\/eurjhf\/hfp103","article-title":"The prognostic significance of heart failure with preserved left ventricular ejection fraction: a literature-based meta-analysis","volume":"11","author":"Somaratne","year":"2009","journal-title":"Eur J Heart Fail"},{"key":"2026011921151609100_ejhfhft024-bib-0020","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1093\/eurjhf\/hfs026","article-title":"Gender and survival in patients with heart failure: interactions with diabetes and aetiology. 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