{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T05:22:03Z","timestamp":1793164923341,"version":"4.5.0"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T00:00:00Z","timestamp":1617062400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill & Melinda Gates Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005411","name":"Foundation for Education and European Culture","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005411","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Miguel Servet programme","award":["CP18\/00006"],"award-info":[{"award-number":["CP18\/00006"]}]},{"name":"Fondos Europeos de Desarrollo Regional"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>This study aimed at evaluating the age, sex, and country-income patterns in aortic aneurysm disease burden, analysing trends in mortality and years of life lost (YLLs), as well as their causal drivers and risk factors, using the 2017 Global Burden of Diseases, Injuries, and Risk Factors Study (GBD 2017).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>We described the temporal, global, and regional (195 countries) patterns of aortic aneurysm (thoracic and abdominal) mortality, YLLs, their drivers [sociodemographic index (SDI), healthcare access and quality index (HAQ index)] and risk factors using the GBD 1990\u20132017. Correlation and mixed multilevel modelling between aortic aneurysm mortality, YLLs, HAQ index and other variables were applied. From 1990 to 2017, a global declining trend in age-standardized aortic aneurysm mortality was found [2.88 deaths\/100\u00a0000 (95% uncertainty intervals, UI 2.79 to 3.03) in 1990 and 2.19 deaths\/100\u00a0000 (95% UI 2.09 to 2.28) in 2017]. Among high-income countries (HICs) a consistent declining Spearman\u2019s correlation between age-standardised aortic aneurysm mortality, SDI (HICs; 1990 rho: 0.57, P \u2264 0.001; 2017 rho: 0.41, P = 0.001) and HAQ index was observed (HICs; 1990 rho: 0.50, P &amp;lt;0.001; 2016 rho: 0.35, P\u2009=\u20090.006); in comparison with low- and middle-income countries where correlation trends were weak and mixed. At a global level, higher HAQ index was related with lower aortic aneurysm mortality and YLLs [mortality, coef: \u22120.05, 95% confidence interval (CI): \u22120.06, \u22120.04; YLLs, coef: \u22120.94, 95% CI: \u22121.17, \u22120.71].<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Age-standardized aortic aneurysm mortality declined globally between 1990 and 2017. Globally, age-standardized aortic aneurysm mortality and YLLs were related to changes in SDI and HAQ index levels, while country-level income-related variations were also observed.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/eurjpc\/zwab015","type":"journal-article","created":{"date-parts":[[2021,2,3]],"date-time":"2021-02-03T18:15:29Z","timestamp":1612376129000},"page":"1220-1232","source":"Crossref","is-referenced-by-count":41,"title":["Global, regional, and national burden of aortic aneurysm, 1990\u20132017: a systematic analysis of the Global Burden of Disease Study 2017"],"prefix":"10.1093","volume":"29","author":[{"given":"Stefanos","family":"Tyrovolas","sequence":"first","affiliation":[{"name":"Parc Sanitari Sant Joan de D\u00e9u, Universitat de Barcelona, Fundaci\u00f3 Sant Joan de D\u00e9u , Dr Antoni Pujades, 42, 08830 Sant Boi de Llobregat, Barcelona, Spain"},{"name":"Instituto de Salud Carlos III, Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental, CIBERSAM , Monforte de Lemos 3-5, Pabell\u00f3n 11, 28029 Madrid, Spain"},{"name":"Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University , 70 Eleutheriou Venizelou str, 17671 Athens, Greece"},{"name":"WHO Collaborating Centre for Community Health Services (WHOCC), School of Nursing, The Hong Kong Polytechnic University , 11 Yuk Choi Rd, Hong Kong SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitra","family":"Tyrovola","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University , 70 Eleutheriou Venizelou str, 17671 Athens, Greece"},{"name":"State Cardiology Clinic, Hippokration General Hospital , 114 Vasilissis Sofias avenue, 11527 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iago","family":"Gin\u00e9-V\u00e1zquez","sequence":"additional","affiliation":[{"name":"Parc Sanitari Sant Joan de D\u00e9u, Universitat de Barcelona, Fundaci\u00f3 Sant Joan de D\u00e9u , Dr Antoni Pujades, 42, 08830 Sant Boi de Llobregat, Barcelona, Spain"},{"name":"Instituto de Salud Carlos III, Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental, CIBERSAM , Monforte de Lemos 3-5, Pabell\u00f3n 11, 28029 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ai","family":"Koyanagi","sequence":"additional","affiliation":[{"name":"Parc Sanitari Sant Joan de D\u00e9u, Universitat de Barcelona, Fundaci\u00f3 Sant Joan de D\u00e9u , Dr Antoni Pujades, 42, 08830 Sant Boi de Llobregat, Barcelona, Spain"},{"name":"Instituto de Salud Carlos III, Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental, CIBERSAM , Monforte de Lemos 3-5, Pabell\u00f3n 11, 28029 Madrid, Spain"},{"name":"ICREA , Pg. Lluis Companys 23, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Bernabe-Ortiz","sequence":"additional","affiliation":[{"name":"CRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia , Av. Armendariz 445, Miraflores, Lima 15074, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Rodriguez-Artalejo","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine and Public Health, School of Medicine, Universidad Aut\u00f3noma de Madrid\/IdiPAZ , calle de Arzobispo Morcillo 4, 28029 Madrid, Spain"},{"name":"CIBER of Epidemiology and Public Health (CIBERESP), IMDEA-Food , calle de Melchor Fernandez Almargo 3, 28029 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep Maria","family":"Haro","sequence":"additional","affiliation":[{"name":"Parc Sanitari Sant Joan de D\u00e9u, Universitat de Barcelona, Fundaci\u00f3 Sant Joan de D\u00e9u , Dr Antoni Pujades, 42, 08830 Sant Boi de Llobregat, Barcelona, Spain"},{"name":"Instituto de Salud Carlos III, Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental, CIBERSAM , Monforte de Lemos 3-5, Pabell\u00f3n 11, 28029 Madrid, Spain"},{"name":"King Saud University , Riyadh 11451, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William K","family":"Pan","sequence":"additional","affiliation":[{"name":"Nicholas School of the Environment, Duke University , 9 Circuit Dr., Durham, NC 27708, USA"},{"name":"Global Health Institute, Duke University , 310 Trent Dr., Durham, NC 27708, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J Jaime","family":"Miranda","sequence":"additional","affiliation":[{"name":"CRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia , Av. 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