{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T22:59:21Z","timestamp":1792364361649,"version":"4.4.0"},"reference-count":44,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T00:00:00Z","timestamp":1662422400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Cardiac rehabilitation (CR) not only improves cardiovascular outcomes, but also health-related quality of life (HRQOL). Unfortunately, CR is still underutilized, especially among women and older patients. Aim of this study was to highlight age- and sex-specific effects of inpatient CR on HRQOL.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>From 2012 to 2018, 18 459 patients were prospectively assessed in six Swiss CR clinics. Of these, we retrospectively analysed a final sample of 8286 patients with a mean (standard deviation) age of 67.8 (11.3) in men and 72.2 (11.3) in women. HRQOL was measured at CR entry and discharge. In multivariable analyses, sex- and age-specific changes in HRQOL throughout CR were estimated, adjusting for baseline HRQOL and clinical characteristics. Participants of both sexes improved significantly (P &amp;lt; 0.001) in all domains of HRQOL during CR. Women reported significantly lower social (P &amp;lt; 0.001) and emotional (P &amp;lt; 0.001) HRQOL than men at CR entry. Female sex predicted greater improvement in social (F = 19.63, P &amp;lt; 0.001), emotional (F = 27.814, P &amp;lt; 0.001), and physical HRQOL (F = 20.473, P &amp;lt; 0.001). In a subgroup of n = 2632 elderly patients (&amp;gt;75 years), female sex predicted greater changes in emotional (F = 15.738, P &amp;lt; 0.001) and physical (F = 6.295, P = 0.012), but not in social HRQOL.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Women report poorer HRQOL at CR entry compared with men, but in turn particularly benefit from CR in this regard. Our results indicate that sex- and age-specific needs of patients should be considered.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/eurjpc\/zwac199","type":"journal-article","created":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T03:58:39Z","timestamp":1662436719000},"page":"128-136","source":"Crossref","is-referenced-by-count":8,"title":["Sex and age as predictors of health-related quality of life change in Phase II cardiac rehabilitation"],"prefix":"10.1093","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3037-8584","authenticated-orcid":false,"given":"Lena","family":"Jellestad","sequence":"first","affiliation":[{"name":"Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, University of Zurich , Zurich , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianca","family":"Auschra","sequence":"additional","affiliation":[{"name":"Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, University of Zurich , Zurich , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Zuccarella-Hackl","sequence":"additional","affiliation":[{"name":"Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, University of Zurich , Zurich , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Princip","sequence":"additional","affiliation":[{"name":"Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, University of Zurich , Zurich , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8929-5129","authenticated-orcid":false,"given":"Roland","family":"von K\u00e4nel","sequence":"additional","affiliation":[{"name":"Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, University of Zurich , Zurich , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Euler","sequence":"additional","affiliation":[{"name":"Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, University of Zurich , Zurich , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0694-7719","authenticated-orcid":false,"given":"Matthias","family":"Hermann","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Heart Center, University Hospital Zurich, University of Zurich , Zurich , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,9,6]]},"reference":[{"key":"2023012506480044000_zwac199-B1","author":"Worldo Health Organization 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