{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T17:53:41Z","timestamp":1790358821669,"version":"4.1.0"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"18","license":[{"start":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T00:00:00Z","timestamp":1663027200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"name":"SIREN","award":["U54HG007479"],"award-info":[{"award-number":["U54HG007479"]}]},{"name":"SIBS Genomics","award":["R01NS107900"],"award-info":[{"award-number":["R01NS107900"]}]},{"name":"SIBS Gen Gen","award":["R01NS107900-02S1"],"award-info":[{"award-number":["R01NS107900-02S1"]}]},{"name":"ARISES","award":["R01NS115944-01"],"award-info":[{"award-number":["R01NS115944-01"]}]},{"name":"H3Africa CVD Supplement"},{"name":"CaNVAS"},{"name":"Sub-Saharan Africa Conference on Stroke","award":["1R13NS115395-01A1"],"award-info":[{"award-number":["1R13NS115395-01A1"]}]},{"name":"Training Africans to Lead and Execute Neurological Trials & Studies","award":["D43TW012030"],"award-info":[{"award-number":["D43TW012030"]}]},{"name":"AWI-Gen","award":["U54HG006938"],"award-info":[{"award-number":["U54HG006938"]}]},{"name":"H3Africa Consortium"},{"name":"Department of Science and Technology","award":["DST\/CON 0056\/2014"],"award-info":[{"award-number":["DST\/CON 0056\/2014"]}]},{"name":"Brain Pool Fellowship"},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"crossref"}]},{"name":"SIGHPC Computational and Data Science Fellowship"},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"crossref","award":["214205\/Z\/18\/Z"],"award-info":[{"award-number":["214205\/Z\/18\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,12,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>The relationship between vegetable consumption and hypertension occurrence remains poorly characterized in sub-Saharan Africa. This study assessed the association of vegetable consumption with odds of hypertension among indigenous Africans.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>We harmonized data on prior vegetable consumption and hypertension occurrence (defined as one of the following conditions; systolic blood pressure \u2265140 or diastolic blood pressure \u226590\u2005mmHg or previous diagnosis or use of antihypertensive medications) from 16 445 participants across five African countries (Nigeria, South Africa, Kenya, Ghana and Burkina Faso) in the Stroke Investigative Research and Educational Network and Africa Wits-INDEPTH partnership for Genomic studies. Vegetable consumption (in servings\/week) was classified as \u2018low\u2019 (&amp;lt;6). \u2018moderate\u2019 (6\u201311), \u2018sufficient\u2019 (12\u201329), and \u2018high\u2019 (\u226530). Odds ratios (ORs) and 95% confidence interval (CI) of hypertension were estimated by categories of vegetable consumption (using \u2018low\u2019 consumption as reference), adjusting for sex, age in years, family history of cardiovascular diseases, education, smoking, alcohol use, physical inactivity, body mass index, diabetes mellitus and dyslipidaemia using logistic regressions at P &amp;lt; 0.05. The mean age of participants was 53.0 ( \u00b1 10.7) years, and 7552 (45.9%) were males, whereas 7070 (42.9%) had hypertension. In addition, 6672(40.6%) participants had \u2018low\u2019 vegetable consumption, and 1758(10.7%) had \u2018high\u2019 vegetable consumption. Multivariable-adjusted OR for hypertension by distribution of vegetable consumption (using \u2018low\u2019 consumption as reference) were 1.03 (95% CI: 0.95, 1.12) for \u2018moderate\u2019 consumption; 0.80 (0.73, 0.88) for \u2018sufficient\u2019, and 0.81 (0.72, 0.92) for \u2018high\u2019 consumption, P-for-trend &amp;lt;0.0001.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Indigenous Africans who consumed at least 12 servings of vegetables per week were less likely to be found hypertensive, particularly among males and young adults.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/eurjpc\/zwac208","type":"journal-article","created":{"date-parts":[[2022,9,9]],"date-time":"2022-09-09T23:03:06Z","timestamp":1662764586000},"page":"2359-2371","source":"Crossref","is-referenced-by-count":17,"title":["Frequent vegetable consumption is inversely associated with hypertension among indigenous Africans"],"prefix":"10.1093","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5201-512X","authenticated-orcid":false,"given":"Onoja Matthew","family":"Akpa","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan , 200284, Ibadan , Nigeria"},{"name":"Institute of Cardiovascular Diseases, College of Medicine, University of Ibadan , 200284, Ibadan , Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4825-4934","authenticated-orcid":false,"given":"Akinkunmi Paul","family":"Okekunle","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan , 200284, Ibadan , Nigeria"},{"name":"Department of Medicine, College of Medicine, University of Ibadan , 200284, Ibadan , Nigeria"},{"name":"Department of Food and Nutrition, Seoul National University , 08826, Seoul , Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osahon Jeffery","family":"Asowata","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan , 200284, Ibadan , Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tinashe","family":"Chikowore","sequence":"additional","affiliation":[{"name":"MRC\/Wits Developmental Pathways for Health Research Unit, Department of Paediatrics, Faculty of Health Sciences, University of the Witwatersrand , Johannesburg, 2000 , South Africa"},{"name":"Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand , Johannesburg, 2000 , South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shukri F","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Health and Well-Being Program, African Population and Health Research Center , 00100, Nairobi , Kenya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred","family":"Sarfo","sequence":"additional","affiliation":[{"name":"Department of Medicine, Kwame Nkrumah University of Science and Technology , 00000, Kumasi , Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rufus","family":"Akinyemi","sequence":"additional","affiliation":[{"name":"Neuroscience and Ageing Research Unit, Institute for Advanced Medical Research and Training College of Medicine, University of Ibadan , 200284, Ibadan , Nigeria"},{"name":"Center for Genomic and Precision Medicine, College of Medicine, University of Ibadan , 200284, Ibadan , Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Akpalu","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Ghana Medical School , P.O. Box LG 1181, Legon, Accra , Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kolawole","family":"Wahab","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Ilorin , 240003, Ilorin , Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reginald","family":"Obiako","sequence":"additional","affiliation":[{"name":"Department of Medicine, Ahmadu Bello University , 810107, Zaria , Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morenikeji","family":"Komolafe","sequence":"additional","affiliation":[{"name":"Department of Medicine, Obafemi Awolowo University Teaching Hospital , Ile-Ife , Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukman","family":"Owolabi","sequence":"additional","affiliation":[{"name":"Department of Medicine, Aminu Kano Teaching Hospital , 700233, Kano , Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Godwin 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