{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:27:22Z","timestamp":1740166042549,"version":"3.37.3"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T00:00:00Z","timestamp":1685059200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,8,1]]},"DOI":"10.1093\/eurjpc\/zwad182","type":"journal-article","created":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T18:38:11Z","timestamp":1685126291000},"page":"1015-1016","source":"Crossref","is-referenced-by-count":1,"title":["Antihypertensive treatment targets in older adults: an unsolved dilemma"],"prefix":"10.1093","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2736-2242","authenticated-orcid":false,"given":"Giulia","family":"Rivasi","sequence":"first","affiliation":[{"name":"Hypertension Clinic, Division of Geriatric and Intensive Care Medicine, Careggi Hospital and University of Florence , Largo Brambilla 3, Florence 50139 , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Matteucci","sequence":"additional","affiliation":[{"name":"Hypertension Clinic, Division of Geriatric and Intensive Care Medicine, Careggi Hospital and University of Florence , Largo Brambilla 3, Florence 50139 , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8965-4523","authenticated-orcid":false,"given":"Andrea","family":"Ungar","sequence":"additional","affiliation":[{"name":"Hypertension Clinic, Division of Geriatric and Intensive Care Medicine, Careggi Hospital and University of Florence , Largo Brambilla 3, Florence 50139 , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,5,26]]},"reference":[{"key":"2023080100354028500_zwad182-B1","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1016\/0140-6736(91)92589-T","article-title":"Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension)","volume":"338","author":"Dahl\u00f6f","year":"1991","journal-title":"Lancet (London, England)"},{"key":"2023080100354028500_zwad182-B2","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1016\/S0140-6736(99)10327-1","article-title":"Randomised trial of old and new antihypertensive drugs in elderly patients: cardiovascular mortality and morbidity the Swedish Trial in Old Patients with Hypertension-2 study","volume":"354","author":"Hansson","year":"1999","journal-title":"Lancet (London, England)"},{"key":"2023080100354028500_zwad182-B3","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1056\/NEJMoa0801369","article-title":"Treatment of hypertension in patients 80 years of age or older","volume":"358","author":"Beckett","year":"2008","journal-title":"N Engl J Med"},{"key":"2023080100354028500_zwad182-B4","doi-asserted-by":"crossref","first-page":"419","DOI":"10.7326\/M16-1754","article-title":"Benefits and harms of intensive blood pressure treatment in adults aged 60 years or older: a systematic review and meta-analysis","volume":"166","author":"Weiss","year":"2017","journal-title":"Ann Intern Med"},{"key":"2023080100354028500_zwad182-B5","doi-asserted-by":"crossref","first-page":"3021","DOI":"10.1093\/eurheartj\/ehy339","article-title":"2018 ESC\/ESH Guidelines for the management of arterial hypertension","volume":"39","author":"Williams","year":"2018","journal-title":"Eur Heart J"},{"key":"2023080100354028500_zwad182-B6","doi-asserted-by":"crossref","first-page":"2673","DOI":"10.1001\/jama.2016.7050","article-title":"Intensive vs standard blood pressure control and cardiovascular disease outcomes in adults aged \u226575 years","volume":"315","author":"Williamson","year":"2016","journal-title":"JAMA"},{"key":"2023080100354028500_zwad182-B7","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1056\/NEJMoa2111437","article-title":"Trial of intensive blood-pressure control in older patients with hypertension","volume":"385","author":"Zhang","year":"2021","journal-title":"N Engl J Med"},{"key":"2023080100354028500_zwad182-B8","doi-asserted-by":"crossref","DOI":"10.1093\/eurjpc\/zwad142","article-title":"Achieved systolic blood pressure and cardiovascular outcomes in 60\u201380-year-old patients: the Strategy of Blood Pressure Intervention in the Elderly Hypertensive Patients (STEP) trial","volume":"30","author":"Deng","year":"2023","journal-title":"Eur J Prev Cardiol"},{"key":"2023080100354028500_zwad182-B9","doi-asserted-by":"crossref","first-page":"M146","DOI":"10.1093\/gerona\/56.3.M146","article-title":"Frailty in older adults: evidence for a phenotype","volume":"56","author":"Fried","year":"2001","journal-title":"J Gerontol Ser A Biol Sci Med Sci"},{"key":"2023080100354028500_zwad182-B10","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1111\/jgs.15236","article-title":"Syncope, hypotension, and falls in the treatment of hypertension: results from the randomized clinical systolic blood pressure intervention trial","volume":"66","author":"Sink","year":"2018","journal-title":"J Am Geriatr Soc"},{"key":"2023080100354028500_zwad182-B11","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.ijcard.2016.06.118","article-title":"Effects of biological age on the associations of blood pressure with cardiovascular and non-cardiovascular mortality in old age: a population-based study","volume":"220","author":"Liang","year":"2016","journal-title":"Int J Cardiol"},{"key":"2023080100354028500_zwad182-B12","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1001\/archinternmed.2012.2555","article-title":"Rethinking the association of high blood pressure with mortality in elderly adults","volume":"172","author":"Odden","year":"2012","journal-title":"Arch Intern Med"},{"key":"2023080100354028500_zwad182-B13","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1093\/ageing\/afv141","article-title":"Blood pressure and 10-year mortality risk in the Milan geriatrics 75+ cohort study: role of functional and cognitive status","volume":"44","author":"Ogliari","year":"2015","journal-title":"Age Ageing"},{"key":"2023080100354028500_zwad182-B14","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1001\/jamainternmed.2014.8164","article-title":"Effects of low blood pressure in cognitively impaired elderly patients treated with antihypertensive drugs","volume":"175","author":"Mossello","year":"2015","journal-title":"JAMA Intern Med"},{"key":"2023080100354028500_zwad182-B15","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1097\/HJH.0000000000002685","article-title":"Hypertension management in frail older adults: a gap in evidence","volume":"39","author":"Rivasi","year":"2021","journal-title":"J Hypertens"}],"container-title":["European Journal of Preventive Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/eurjpc\/advance-article-pdf\/doi\/10.1093\/eurjpc\/zwad182\/50569266\/zwad182.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurjpc\/article-pdf\/30\/10\/1015\/51012342\/zwad182.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurjpc\/article-pdf\/30\/10\/1015\/51012342\/zwad182.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:36:23Z","timestamp":1690850183000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurjpc\/article\/30\/10\/1015\/7180802"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,26]]},"references-count":15,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2023,5,26]]},"published-print":{"date-parts":[[2023,8,1]]}},"URL":"https:\/\/doi.org\/10.1093\/eurjpc\/zwad182","relation":{},"ISSN":["2047-4873","2047-4881"],"issn-type":[{"type":"print","value":"2047-4873"},{"type":"electronic","value":"2047-4881"}],"subject":[],"published-other":{"date-parts":[[2023,8]]},"published":{"date-parts":[[2023,5,26]]}}}