{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T18:39:58Z","timestamp":1787942398295,"version":"build-2784847793"},"reference-count":76,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T00:00:00Z","timestamp":1693785600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003793","name":"Swedish Heart-Lung Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Research Funds at Sk\u00e5ne University Hospital"},{"DOI":"10.13039\/501100009780","name":"Region Sk\u00e5ne","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009780","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Hulda Ahlmroth Foundation"},{"name":"Swedish Government"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>The aim of this study is to investigate how genetic variations in genes related to oxidative stress, intake of antioxidant vitamins, and any potential interactions between these factors affect the incidence of intact abdominal aortic aneurysm (AAA) and its rupture (rAAA), accounting for sex differences where possible.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>The present retrospective cohort study (n = 25 252) uses baseline single-nucleotide polymorphisms (SNPs) and total antioxidant vitamin intake data from the large population-based, Malm\u00f6 Diet and Cancer Study. Cumulative incidence of intact AAA was 1.6% and of rAAA 0.3% after a median follow-up of 24.3 years. A variant in NOX3 (rs3749930) was associated with higher rAAA risk in males [adjusted hazard ratio (aHR): 2.49; 95% confidence interval (CI): 1.36\u20134.35] and the overall population (aHR: 1.88; 95% CI: 1.05\u20133.37). Higher intakes of antioxidant vitamins, riboflavin, and folate were associated with 20% and 19% reduced intact AAA incidence, respectively. Interestingly, the inverse associations between riboflavin and vitamin D intake with intact AAA incidence were stronger in the individuals carrying the NOX3 variant as compared with the wild-type recessive genotype, i.e. by 60% and 66%, respectively (P for interaction &amp;lt; 0.05). Higher riboflavin intake was associated with a 33% male-specific intact AAA risk reduction, while higher intake of vitamin B12 intake was associated with 55% female-specific intact AAA risk increase; both these associations were significantly modified by sex (P for interaction &amp;lt; 0.05).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Our findings highlight the role of oxidative stress genetic variations and antioxidant vitamin intake in AAA. Although a low AAA\/rAAA sample size limited some analyses, especially in females, our findings highlight the need for future randomized controlled trials and mechanistic studies, to explore the potential benefits of antioxidant vitamins while accounting for genetic and sex differences.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/eurjpc\/zwad271","type":"journal-article","created":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T20:10:15Z","timestamp":1693858215000},"page":"61-74","source":"Crossref","is-referenced-by-count":12,"title":["Oxidative stress\u2013related genetic variation and antioxidant vitamin intake in intact and ruptured abdominal aortic aneurysm: a Swedish population-based retrospective cohort study"],"prefix":"10.1093","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3419-6446","authenticated-orcid":false,"given":"Sakshi","family":"Vats","sequence":"first","affiliation":[{"name":"Center for Primary Health Care Research, Wallenberg Laboratory , 5th floor, Inga Marie Nilsson's gata 53, 214 28, Malm\u00f6 , Sweden"},{"name":"Center for Primary Health Care Research, Department of Clinical Sciences, Lund University\/Region Sk\u00e5ne , Malm\u00f6 , Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8031-279X","authenticated-orcid":false,"given":"Kristina","family":"Sundquist","sequence":"additional","affiliation":[{"name":"Center for Primary Health Care Research, Department of Clinical Sciences, Lund University\/Region Sk\u00e5ne , Malm\u00f6 , Sweden"},{"name":"Department of Family Medicine and Community Health, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai , New York , USA"},{"name":"Center for Community-Based Healthcare Research and Education (CoHRE), Department of Functional Pathology, School of Medicine, Shimane University , Matsue , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7228-5015","authenticated-orcid":false,"given":"Jan","family":"Sundquist","sequence":"additional","affiliation":[{"name":"Center for Primary Health Care Research, Department of Clinical Sciences, Lund University\/Region Sk\u00e5ne , Malm\u00f6 , Sweden"},{"name":"Department of Family Medicine and Community Health, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai , New York , USA"},{"name":"Center for Community-Based Healthcare Research and Education (CoHRE), Department of Functional Pathology, School of Medicine, Shimane University , Matsue , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naiqi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Center for Primary Health Care Research, Department of Clinical Sciences, Lund University\/Region Sk\u00e5ne , Malm\u00f6 , Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Wang","sequence":"additional","affiliation":[{"name":"Center for Primary Health Care Research, Department of Clinical Sciences, Lund University\/Region Sk\u00e5ne , Malm\u00f6 , Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Acosta","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Lund University , Malm\u00f6 , Sweden"},{"name":"Vascular Centre, Department of Cardiothoracic and Vascular Surgery, Sk\u00e5ne University Hospital , Lund University, Malm\u00f6, S-205 02 , Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Gotts\u00e4ter","sequence":"additional","affiliation":[{"name":"Vascular Centre, Department of Cardiothoracic and Vascular Surgery, Sk\u00e5ne University Hospital , Lund University, Malm\u00f6, S-205 02 , Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashfaque A","family":"Memon","sequence":"additional","affiliation":[{"name":"Center for Primary Health Care Research, Department of Clinical Sciences, Lund University\/Region Sk\u00e5ne , Malm\u00f6 , Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,9,4]]},"reference":[{"key":"2024010504412201500_zwad271-B1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ejvs.2018.09.020","article-title":"Editor's choice\u2014European Society for Vascular Surgery (ESVS) 2019 clinical practice guidelines on the management of abdominal aorto-iliac artery aneurysms","volume":"57","author":"Wanhainen","year":"2019","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"2024010504412201500_zwad271-B2","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1097\/SLA.0000000000005716","article-title":"The global and regional prevalence of abdominal aortic aneurysms: a systematic review and modelling analysis","volume":"277","author":"Song","year":"2022","journal-title":"Ann Surg"},{"key":"2024010504412201500_zwad271-B3","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1002\/bjs.8707","article-title":"Meta-analysis of individual patient data to examine factors affecting growth and rupture of small abdominal aortic aneurysms","volume":"99","author":"Sweeting","year":"2012","journal-title":"Br J Surg"},{"key":"2024010504412201500_zwad271-B4","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1002\/bjs.9838","article-title":"Age-specific incidence, risk factors and outcome of acute abdominal aortic aneurysms in a defined population","volume":"102","author":"Howard","year":"2015","journal-title":"Br J Surg"},{"key":"2024010504412201500_zwad271-B5","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1002\/bjs.9235","article-title":"Systematic review and meta-analysis of population-based mortality from ruptured abdominal aortic aneurysm","volume":"100","author":"Reimerink","year":"2013","journal-title":"Br J Surg"},{"key":"2024010504412201500_zwad271-B6","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.jvs.2017.10.044","article-title":"The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm","volume":"67","author":"Chaikof","year":"2018","journal-title":"J Vasc Surg"},{"key":"2024010504412201500_zwad271-B7","doi-asserted-by":"crossref","first-page":"1245049","DOI":"10.1155\/2016\/1245049","article-title":"Role of ROS and RNS sources in physiological and pathological conditions","volume":"2016","author":"Di Meo","year":"2016","journal-title":"Oxid Med Cell Longev"},{"key":"2024010504412201500_zwad271-B8","doi-asserted-by":"crossref","first-page":"2389","DOI":"10.1016\/j.ijcard.2013.01.278","article-title":"Mechanisms of oxidative stress in human aortic aneurysms\u2014association with clinical risk factors for atherosclerosis and disease severity","volume":"168","author":"Guzik","year":"2013","journal-title":"Int J Cardiol"},{"key":"2024010504412201500_zwad271-B9","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1161\/01.ATV.0000257552.94483.14","article-title":"Role of oxidative stress in the pathogenesis of abdominal aortic aneurysms","volume":"27","author":"McCormick","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"2024010504412201500_zwad271-B10","doi-asserted-by":"crossref","first-page":"H1168","DOI":"10.1152\/ajpheart.00296.2017","article-title":"Role of myeloperoxidase in abdominal aortic aneurysm formation: mitigation by taurine","volume":"313","author":"Kim","year":"2017","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"2024010504412201500_zwad271-B11","doi-asserted-by":"crossref","first-page":"3196S","DOI":"10.1093\/jn\/134.11.3196S","article-title":"Efficacy of dietary antioxidants to prevent oxidative damage and inhibit chronic disease","volume":"134","author":"Frei","year":"2004","journal-title":"J Nutr"},{"key":"2024010504412201500_zwad271-B12","doi-asserted-by":"crossref","first-page":"2521","DOI":"10.1042\/CS20200980","article-title":"Vitamin D deficiency promotes large rupture-prone abdominal aortic aneurysms and cholecalciferol supplementation limits progression of aneurysms in a mouse model","volume":"134","author":"Nsengiyumva","year":"2020","journal-title":"Clin Sci"},{"key":"2024010504412201500_zwad271-B13","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1161\/01.ATV.0000172631.50972.0f","article-title":"Vitamin E inhibits abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice","volume":"25","author":"Gavrila","year":"2005","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"2024010504412201500_zwad271-B14","doi-asserted-by":"crossref","first-page":"e88899","DOI":"10.1371\/journal.pone.0088899","article-title":"Recoupling of eNOS with folic acid prevents abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E null mice","volume":"9","author":"Siu","year":"2014","journal-title":"PLoS One"},{"key":"2024010504412201500_zwad271-B15","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.jvs.2015.03.045","article-title":"Endogenous superoxide dismutase activation by oral administration of riboflavin reduces abdominal aortic aneurysm formation in rats","volume":"64","author":"Yu","year":"2016","journal-title":"J Vasc Surg"},{"key":"2024010504412201500_zwad271-B16","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.ejvs.2021.04.017","article-title":"Mediterranean diet is associated with reduced risk of abdominal aortic aneurysm in smokers: results of two prospective cohort studies","volume":"62","author":"Kaluza","year":"2021","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"2024010504412201500_zwad271-B17","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1007\/s00394-019-02054-w","article-title":"Intake of fibre and plant foods and the risk of abdominal aortic aneurysm in a large prospective cohort study in Sweden","volume":"59","author":"Bergwall","year":"2020","journal-title":"Eur J Nutr"},{"key":"2024010504412201500_zwad271-B18","doi-asserted-by":"crossref","first-page":"e003768","DOI":"10.1161\/JAHA.116.003768","article-title":"Folic acid supplementation and the risk of cardiovascular diseases: a meta-analysis of randomized controlled trials","volume":"5","author":"Li","year":"2016","journal-title":"J Am Heart Assoc"},{"key":"2024010504412201500_zwad271-B19","doi-asserted-by":"crossref","first-page":"5345","DOI":"10.3390\/nu14245345","article-title":"Riboflavin intake inversely associated with cardiovascular-disease mortality and interacting with folate intake: findings from the National Health and Nutrition Examination Survey (NHANES) 2005\u20132016","volume":"14","author":"Li","year":"2022","journal-title":"Nutrients"},{"key":"2024010504412201500_zwad271-B20","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1038\/s41598-022-05632-x","article-title":"Associations between dietary antioxidant intakes and cardiovascular disease","volume":"12","author":"Mirmiran","year":"2022","journal-title":"Sci Rep"},{"key":"2024010504412201500_zwad271-B21","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.3390\/nu12072014","article-title":"Hyperhomocysteinemia and low folate and vitamin B12 are associated with vascular dysfunction and impaired nitric oxide sensitivity in morbidly obese patients","volume":"12","author":"Haloul","year":"2020","journal-title":"Nutrients"},{"key":"2024010504412201500_zwad271-B22","doi-asserted-by":"crossref","first-page":"e0166869","DOI":"10.1371\/journal.pone.0166869","article-title":"High vitamin D consumption is inversely associated with cardiovascular disease risk in an urban Mexican population","volume":"11","author":"Mu\u00f1oz-Aguirre","year":"2016","journal-title":"PLoS One"},{"key":"2024010504412201500_zwad271-B23","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.1016\/j.jacc.2022.09.048","article-title":"Micronutrient supplementation to reduce cardiovascular risk","volume":"80","author":"An","year":"2022","journal-title":"J Am Coll Cardiol"},{"key":"2024010504412201500_zwad271-B24","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1111\/jhn.12748","article-title":"Dietary vitamin D intake, cardiovascular disease and cardiometabolic risk factors: a sex-based analysis from the ATTICA cohort study","volume":"33","author":"Kouvari","year":"2020","journal-title":"J Hum Nutr Diet"},{"key":"2024010504412201500_zwad271-B25","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1056\/NEJM200001203420302","article-title":"Vitamin E supplementation and cardiovascular events in high-risk patients","volume":"342","author":"Yusuf","year":"2000","journal-title":"N Engl J Med"},{"key":"2024010504412201500_zwad271-B26","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/S0753-3322(99)80120-6","article-title":"Beta-carotene and risk of coronary heart disease. A review of observational and intervention studies","volume":"53","author":"Tavani","year":"1999","journal-title":"Biomed Pharmacother"},{"key":"2024010504412201500_zwad271-B27","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s12263-016-0536-0","article-title":"Genetic susceptibility to dyslipidemia and incidence of cardiovascular disease depending on a diet quality index in the Malm\u00f6 Diet and Cancer Cohort","volume":"11","author":"Hellstrand","year":"2016","journal-title":"Genes Nutr"},{"key":"2024010504412201500_zwad271-B28","doi-asserted-by":"crossref","first-page":"18405","DOI":"10.1038\/s41598-019-54938-w","article-title":"The Mediterranean diet reduces the genetic risk of chromosome 9p21 for myocardial infarction in an Asian population community cohort","volume":"9","author":"Leu","year":"2019","journal-title":"Sci Rep"},{"key":"2024010504412201500_zwad271-B29","doi-asserted-by":"crossref","first-page":"948691","DOI":"10.3389\/fnut.2022.948691","article-title":"Association between serum 25-hydroxyvitamin d and myeloperoxidase: a cross-sectional study of a general population in China","volume":"9","author":"Zhou","year":"2022","journal-title":"Front Nutr"},{"key":"2024010504412201500_zwad271-B30","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1161\/hy09t1.094005","article-title":"Antioxidant effects of vitamins C and E are associated with altered activation of vascular NADPH oxidase and superoxide dismutase in stroke-prone SHR","volume":"38","author":"Chen","year":"2001","journal-title":"Hypertension"},{"key":"2024010504412201500_zwad271-B31","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.atherosclerosis.2012.06.057","article-title":"Sexual dimorphism of abdominal aortic aneurysms: a striking example of \u201cmale disadvantage\u201d in cardiovascular disease","volume":"225","author":"Bloomer","year":"2012","journal-title":"Atherosclerosis"},{"key":"2024010504412201500_zwad271-B32","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1161\/01.CIR.0000050626.25057.51","article-title":"Six-year effect of combined vitamin C and E supplementation on atherosclerotic progression","volume":"107","author":"Salonen","year":"2003","journal-title":"Circulation"},{"key":"2024010504412201500_zwad271-B33","doi-asserted-by":"crossref","first-page":"e2","DOI":"10.1017\/jns.2020.54","article-title":"Gender difference in the association of dietary intake of antioxidant vitamins with kidney function in middle-aged and elderly Japanese","volume":"10","author":"Hara","year":"2021","journal-title":"J Nutr Sci"},{"key":"2024010504412201500_zwad271-B34","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1177\/1559827620972035","article-title":"The VITamin D and OmegA-3 TriaL (VITAL): do results differ by sex or race\/ethnicity?","volume":"15","author":"Bassuk","year":"2021","journal-title":"Am J Lifestyle Med"},{"key":"2024010504412201500_zwad271-B35","first-page":"100152","article-title":"Sex-dimorphic gene effects on survival outcomes in people with coronary artery disease","volume":"17","author":"Dungan","year":"2022","journal-title":"Am Heart J Plus"},{"key":"2024010504412201500_zwad271-B36","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1136\/jim-2016-000404","article-title":"A DAB2IP genotype: sex interaction is associated with abdominal aortic aneurysm expansion","volume":"65","author":"Ye","year":"2017","journal-title":"J Investig Med"},{"key":"2024010504412201500_zwad271-B37","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1111\/jcmm.13038","article-title":"Gender difference in oxidative stress: a new look at the mechanisms for cardiovascular diseases","volume":"21","author":"Kander","year":"2017","journal-title":"J Cell Mol Med"},{"key":"2024010504412201500_zwad271-B38","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1177\/14034948020300020401","article-title":"Invitation to a population-based cohort study: differences between subjects recruited using various strategies","volume":"30","author":"Manjer","year":"2002","journal-title":"Scand J Public Health"},{"key":"2024010504412201500_zwad271-B39","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1186\/1471-2458-11-450","article-title":"External review and validation of the Swedish national inpatient register","volume":"11","author":"Ludvigsson","year":"2011","journal-title":"BMC Public Health"},{"key":"2024010504412201500_zwad271-B40","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1177\/0003319720946976","article-title":"Comparisons of risk factors for abdominal aortic aneurysm and coronary heart disease: a prospective cohort study","volume":"72","author":"Xiao","year":"2021","journal-title":"Angiology"},{"key":"2024010504412201500_zwad271-B41","doi-asserted-by":"crossref","first-page":"2738","DOI":"10.1161\/ATVBAHA.120.314856","article-title":"Genome-wide polygenic score, clinical risk factors, and long-term trajectories of coronary artery disease","volume":"40","author":"Hindy","year":"2020","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"2024010504412201500_zwad271-B42","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1038\/ng.3643","article-title":"A reference panel of 64,976 haplotypes for genotype imputation","volume":"48","author":"Kretzschmar","year":"2016","journal-title":"Nat Genet"},{"key":"2024010504412201500_zwad271-B43","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1038\/ejhg.2017.130","article-title":"SweGen: a whole-genome data resource of genetic variability in a cross-section of the Swedish population","volume":"25","author":"Ameur","year":"2017","journal-title":"Eur J Hum Genet"},{"key":"2024010504412201500_zwad271-B44","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/nmeth0410-248","article-title":"A method and server for predicting damaging missense mutations","volume":"7","author":"Adzhubei","year":"2010","journal-title":"Nat Methods"},{"key":"2024010504412201500_zwad271-B45","doi-asserted-by":"crossref","first-page":"3812","DOI":"10.1093\/nar\/gkg509","article-title":"SIFT: predicting amino acid changes that affect protein function","volume":"31","author":"Ng","year":"2003","journal-title":"Nucleic Acids Res"},{"key":"2024010504412201500_zwad271-B46","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/nprot.2015.123","article-title":"SIFT missense predictions for genomes","volume":"11","author":"Vaser","year":"2016","journal-title":"Nat Protoc"},{"key":"2024010504412201500_zwad271-B47","doi-asserted-by":"crossref","first-page":"5918","DOI":"10.1038\/s41467-020-19669-x","article-title":"Inferring the molecular and phenotypic impact of amino acid variants with MutPred2","volume":"11","author":"Pejaver","year":"2020","journal-title":"Nat Commun"},{"key":"2024010504412201500_zwad271-B48","doi-asserted-by":"crossref","first-page":"S161","DOI":"10.1093\/ije\/26.suppl_1.S161","article-title":"The Malm\u00f6 Food Study: validity of two dietary assessment methods for measuring nutrient intake","volume":"26","author":"Riboli","year":"1997","journal-title":"Int J Epidemiol"},{"key":"2024010504412201500_zwad271-B49","first-page":"143","article-title":"The Malm\u00f6 Food Study: the relative validity of a modified diet history method and an extensive food frequency questionnaire for measuring food intake","volume":"50","author":"Elmst\u00e5hl","year":"1996","journal-title":"Eur J Clin Nutr"},{"key":"2024010504412201500_zwad271-B50","first-page":"134","article-title":"The Malm\u00f6 Food Study: the reproducibility of a novel diet history method and an extensive food frequency questionnaire","volume":"50","author":"Elmst\u00e5hl","year":"1996","journal-title":"Eur J Clin Nutr"},{"key":"2024010504412201500_zwad271-B51","doi-asserted-by":"crossref","first-page":"1359S","DOI":"10.1093\/jn\/131.4.1359S","article-title":"Factors in aging that effect the bioavailability of nutrients","volume":"131","author":"Russell","year":"2001","journal-title":"J Nutr"},{"key":"2024010504412201500_zwad271-B52","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1017\/S0007114522000149","article-title":"Sex differences in vitamin D metabolism, serum levels and action","volume":"128","author":"Wierzbicka","year":"2022","journal-title":"Br J Nutr"},{"key":"2024010504412201500_zwad271-B53","doi-asserted-by":"crossref","first-page":"2805","DOI":"10.3390\/ijerph15122805","article-title":"Risk factors for abdominal aortic aneurysm in population-based studies: a systematic review and meta-analysis","volume":"15","author":"Altobelli","year":"2018","journal-title":"Int J Environ Res Public Health"},{"key":"2024010504412201500_zwad271-B54","doi-asserted-by":"crossref","first-page":"4259","DOI":"10.3390\/ijerph18084259","article-title":"Regression with highly correlated predictors: variable omission is not the solution","volume":"18","author":"Gregorich","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"2024010504412201500_zwad271-B55"},{"key":"2024010504412201500_zwad271-B56","doi-asserted-by":"crossref","first-page":"e1859","DOI":"10.1002\/mgg3.1859","article-title":"Neutrophil cytosolic factor 2 (NCF2) gene polymorphism is associated with juvenile-onset systemic lupus erythematosus, but probably not with other autoimmune rheumatic diseases in children","volume":"10","author":"Bakutenko","year":"2022","journal-title":"Mol Genet Genomic Med"},{"key":"2024010504412201500_zwad271-B57","doi-asserted-by":"crossref","first-page":"875434","DOI":"10.3389\/fcvm.2022.875434","article-title":"Key ferroptosis-related genes in abdominal aortic aneurysm formation and rupture as determined by combining bioinformatics techniques","volume":"9","author":"Ren","year":"2022","journal-title":"Front Cardiovasc Med"},{"key":"2024010504412201500_zwad271-B58","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.jtcvs.2014.09.077","article-title":"Oxidant stress regulatory genetic variation in recipients and donors contributes to risk of primary graft dysfunction after lung transplantation","volume":"149","author":"Cantu","year":"2015","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2024010504412201500_zwad271-B59","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1139\/cjpp-2019-0055","article-title":"Increase of NADPH oxidase 3 in heart failure of hereditary cardiomyopathy","volume":"97","author":"Bkaily","year":"2019","journal-title":"Can J Physiol Pharmacol"},{"key":"2024010504412201500_zwad271-B60","doi-asserted-by":"crossref","first-page":"101488","DOI":"10.1016\/j.redox.2020.101488","article-title":"Sex differences in the response to oxidative and proteolytic stress","volume":"31","author":"Tower","year":"2020","journal-title":"Redox Biol"},{"key":"2024010504412201500_zwad271-B61","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.3390\/antiox11061088","article-title":"Myeloperoxidase and advanced oxidation protein products in the cerebrospinal fluid in women and men with Parkinson\u2019s disease","volume":"11","author":"Fern\u00e1ndez-Espejo","year":"2022","journal-title":"Antioxidants"},{"key":"2024010504412201500_zwad271-B62","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1161\/01.ATV.0000013778.72404.30","article-title":"Oxidative stress in human abdominal aortic aneurysms","volume":"22","author":"Miller","year":"2002","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"2024010504412201500_zwad271-B63","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0021-9150(00)00694-8","article-title":"Alpha-tocopherol (vitamin E) and beta-carotene supplementation does not affect the risk for large abdominal aortic aneurysm in a controlled trial","volume":"157","author":"T\u00f6rnwall","year":"2001","journal-title":"Atherosclerosis"},{"key":"2024010504412201500_zwad271-B64","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s12291-017-0699-5","article-title":"Nutrigenomics and nutrigenetics: new insight in disease prevention and cure","volume":"32","author":"Sharma","year":"2017","journal-title":"Indian J Clin Biochem"},{"key":"2024010504412201500_zwad271-B65","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1373\/49.2.295","article-title":"Effect of riboflavin status on the homocysteine-lowering effect of folate in relation to the MTHFR (C677T) genotype","volume":"49","author":"Moat","year":"2003","journal-title":"Clin Chem"},{"key":"2024010504412201500_zwad271-B66","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.ijcard.2020.06.022","article-title":"Associations of global DNA methylation and homocysteine levels with abdominal aortic aneurysm: a cohort study from a population-based screening program in Sweden","volume":"321","author":"Vats","year":"2020","journal-title":"Int J Cardiol"},{"key":"2024010504412201500_zwad271-B67","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1161\/CIRCRESAHA.112.270520","article-title":"Hyperhomocysteinemia exaggerates adventitial inflammation and angiotensin II\u2212induced abdominal aortic aneurysm in mice","volume":"111","author":"Liu","year":"2012","journal-title":"Circ Res"},{"key":"2024010504412201500_zwad271-B68","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/s12944-021-01459-z","article-title":"Gender differences in risk factors for high plasma homocysteine levels based on a retrospective checkup cohort using a generalized estimating equation analysis","volume":"20","author":"Zhao","year":"2021","journal-title":"Lipids Health Dis"},{"key":"2024010504412201500_zwad271-B69","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1017\/S0029665121000550","article-title":"Sex differences in requirements for micronutrients across the lifecourse","volume":"80","author":"Prentice","year":"2021","journal-title":"Proc Nutr Soc"},{"key":"2024010504412201500_zwad271-B70","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1158\/1055-9965.EPI-16-0202","article-title":"Sex-specific associations between one-carbon metabolism indices and posttranslational histone modifications in arsenic-exposed Bangladeshi adults","volume":"26","author":"Howe","year":"2017","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"2024010504412201500_zwad271-B71","doi-asserted-by":"crossref","first-page":"111797","DOI":"10.1016\/j.mad.2023.111797","article-title":"Sex differences in markers of oxidation and inflammation. Implications for ageing","volume":"211","author":"Mart\u00ednez de Toda","year":"2023","journal-title":"Mech Ageing Dev"},{"key":"2024010504412201500_zwad271-B72","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1475-2891-1-3","article-title":"A methodological report from the Malm\u00f6 Diet and Cancer Study: development and evaluation of altered routines in dietary data processing","volume":"1","author":"Wirf\u00e4lt","year":"2002","journal-title":"Nutr J"},{"key":"2024010504412201500_zwad271-B73","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1002\/gepi.20540","article-title":"Meta-analysis of sex-specific genome-wide association studies","volume":"34","author":"Magi","year":"2010","journal-title":"Genet Epidemiol"},{"key":"2024010504412201500_zwad271-B74","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1186\/s40795-022-00628-2","article-title":"Energy intake, expenditure and balance, and factors associated with energy balance of young adults (20\u201339 years): a retrospective cross-sectional community-based cohort study","volume":"8","author":"Ayogu","year":"2022","journal-title":"BMC Nutr"},{"key":"2024010504412201500_zwad271-B75","doi-asserted-by":"crossref","first-page":"4636","DOI":"10.3390\/nu14214636","article-title":"Association between dietary habits, food attitudes, and food security status of US adults since March 2020: a cross-sectional online study","volume":"14","author":"Bin Zarah","year":"2022","journal-title":"Nutrients"},{"key":"2024010504412201500_zwad271-B76","doi-asserted-by":"crossref","first-page":"10582","DOI":"10.3390\/ijerph182010582","article-title":"Dietary changes, motivators, and barriers affecting diet and physical activity among overweight and obese: a mixed methods approach","volume":"18","author":"Helland","year":"2021","journal-title":"Int J Environ Res Public Health"}],"container-title":["European Journal of Preventive Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/eurjpc\/advance-article-pdf\/doi\/10.1093\/eurjpc\/zwad271\/51346777\/zwad271.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurjpc\/article-pdf\/31\/1\/61\/54908379\/zwad271.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurjpc\/article-pdf\/31\/1\/61\/54908379\/zwad271.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,5]],"date-time":"2024-01-05T04:56:14Z","timestamp":1704430574000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurjpc\/article\/31\/1\/61\/7259823"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,4]]},"references-count":76,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,9,4]]},"published-print":{"date-parts":[[2024,1,5]]}},"URL":"https:\/\/doi.org\/10.1093\/eurjpc\/zwad271","relation":{},"ISSN":["2047-4873","2047-4881"],"issn-type":[{"value":"2047-4873","type":"print"},{"value":"2047-4881","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,1]]},"published":{"date-parts":[[2023,9,4]]}}}