{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:07:51Z","timestamp":1790208471942,"version":"4.1.0"},"reference-count":49,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T00:00:00Z","timestamp":1694390400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100014717","name":"National Science Fund for Excellent Young Scholars","doi-asserted-by":"publisher","award":["81922060"],"award-info":[{"award-number":["81922060"]}],"id":[{"id":"10.13039\/100014717","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000274","name":"The British Heart Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000289","name":"Cancer Research UK","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000289","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Denture use may potentially increase the risk of cardiometabolic diseases (CMDs), but the casual relevance and strength of the associations are currently unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>A total of 495 938 participants from the UK Biobank were included in the observational analyses. Linkage disequilibrium score (LDSC) regression and Mendelian randomization analyses were employed to estimate genetic correlation and the associations between the genetic liability for denture use with coronary artery disease, myocardial infarction, heart failure (HF), any stroke (AS), ischaemic stroke, haemorrhagic stroke, type 2 diabetes (T2D), and related clinical risk factors. In observational analysis, denture use was associated with 14\u201325% higher risks of various CMDs. The LDSC analysis found that denture use showed a positive genetic correlation with CMDs (rg 0.21\u20130.38). Genetic liability for denture use was associated with an elevated risk of HF [odds ratio: 1.49 (1.20\u20131.83)] and T2D [1.11 (1.01\u20131.24)]. By integrating genetic summary data of denture use with the sum of decayed, missing, and filled tooth surfaces (DMFS), a clinical measure of dental caries obtained from an independent source, genetically determined denture use\/DMFS was also associated with an elevated risk of AS [1.21 (1.04\u20131.40)]. Furthermore, genetically predicted denture use\/DMFS was significantly associated with established cardiometabolic risk factors, including HDL cholesterol, triglycerides, waist circumference, waist-to-hip ratio, and height.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our study supported potential causal associations between the genetic liability for denture use and risks for HF, AS, T2D, and related clinical risk factors. These findings may inform prevention and intervention strategies targeting dental diseases and CMDs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/eurjpc\/zwad295","type":"journal-article","created":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T08:57:00Z","timestamp":1694249820000},"page":"13-20","source":"Crossref","is-referenced-by-count":10,"title":["Denture use and risk for cardiometabolic disease: observational and Mendelian randomization analyses"],"prefix":"10.1093","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3695-7552","authenticated-orcid":false,"given":"Yunan","family":"Liu","sequence":"first","affiliation":[{"name":"CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences , 320 Yueyang Road, Shanghai 200031 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiqiang","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Neurology, Beijing Tiantan Hospital, Capital Medical University , Beijing 100050 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tongtong","family":"Li","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences , 320 Yueyang Road, Shanghai 200031 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengwu","family":"Feng","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences , 320 Yueyang Road, Shanghai 200031 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Han","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences , 320 Yueyang Road, Shanghai 200031 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaying","family":"Cao","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences , 320 Yueyang Road, Shanghai 200031 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Su","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences , 320 Yueyang Road, Shanghai 200031 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haihao","family":"He","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences , 320 Yueyang Road, Shanghai 200031 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changzheng","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Big Data in Health Science, Zhejiang University School of Public Health , Hangzhou, Zhejiang 310058 , China"},{"name":"Department of Nutrition, Harvard T.H. Chan School of Public Health , Boston, MA 02115 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Sun","sequence":"additional","affiliation":[{"name":"NHS Blood and Transplant (NHSBT) Blood Donor Centre, John Radcliffe Hospital , Oxford OX39BQ , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9183-2253","authenticated-orcid":false,"given":"Robert","family":"Clarke","sequence":"additional","affiliation":[{"name":"Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford , Old Road Campus, Headington, Oxford OX37LF , UK"},{"name":"Medical Research Council, Population Health Research Unit, University of Oxford , Old Road Campus, Headington, Oxford OX37LF , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Gan","sequence":"additional","affiliation":[{"name":"Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford , Old Road Campus, Headington, Oxford OX37LF , UK"},{"name":"Medical Research Council, Population Health Research Unit, University of Oxford , Old Road Campus, Headington, Oxford OX37LF , UK"},{"name":"Genetics Department, Novo Nordisk Research Centre Oxford , Innovation Building, Old Road Campus, Headington, Oxford OX37LQ , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Tonetti","sequence":"additional","affiliation":[{"name":"Shanghai PerioImplant Innovation Center, Department of Oral and Maxillo-facial Implantology, Shanghai Key Laboratory of Stomatology, National Clinical Research Centre for Oral Diseases, Shanghai Ninth People Hospital, Shanghai Jiao Tong University School of Medicine , 639 Zhizaoju Road, Shanghai 200011 , China"},{"name":"European Research Group on Periodontology , WTC Tower Genoa, Via De Marini, 1-16149 Genoa , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0372-8262","authenticated-orcid":false,"given":"Geng","family":"Zong","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences , 320 Yueyang Road, Shanghai 200031 , China"},{"name":"Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People\u2019s Hospital , 600 Yishan Road, Shanghai 200233 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,9,11]]},"reference":[{"key":"2024010504412054600_zwad295-B1","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1177\/0022034520908533","article-title":"Global, regional, and national levels and trends in burden of oral conditions from 1990 to 2017: a systematic analysis for the global burden of disease 2017 study","volume":"99","author":"GBD 2017 Oral Disorders Collaborators","year":"2020","journal-title":"J Dent Res"},{"key":"2024010504412054600_zwad295-B2","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0140-6736(19)31146-8","article-title":"Oral diseases: a global public health challenge","volume":"394","author":"Peres","year":"2019","journal-title":"Lancet"},{"key":"2024010504412054600_zwad295-B3","doi-asserted-by":"crossref","first-page":"2520","DOI":"10.1161\/CIR.0b013e31825719f3","article-title":"Periodontal disease and atherosclerotic vascular disease: does the evidence support an independent association?: a scientific statement from the American Heart Association","volume":"125","author":"Lockhart","year":"2012","journal-title":"Circulation"},{"key":"2024010504412054600_zwad295-B4","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1093\/eurheartj\/ehy836","article-title":"Improved oral hygiene care attenuates the cardiovascular risk of oral health disease: a population-based study from Korea","volume":"40","author":"Park","year":"2019","journal-title":"Eur Heart J"},{"key":"2024010504412054600_zwad295-B5","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1161\/CIRCULATIONAHA.115.020324","article-title":"Periodontitis increases the risk of a first myocardial infarction: a report from the PAROKRANK study","volume":"133","author":"Ryden","year":"2016","journal-title":"Circulation"},{"key":"2024010504412054600_zwad295-B6","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1177\/2047487315621978","article-title":"Tooth loss is independently associated with poor outcomes in stable coronary heart disease","volume":"23","author":"Vedin","year":"2016","journal-title":"Eur J Prev Cardiol"},{"key":"2024010504412054600_zwad295-B7","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/jcpe.13599","article-title":"Periodontal disease and incident prediabetes and diabetes: the Hispanic community health study\/study of Latinos","volume":"49","author":"Laniado","year":"2022","journal-title":"J Clin Periodontol"},{"key":"2024010504412054600_zwad295-B8","doi-asserted-by":"crossref","first-page":"204","DOI":"10.2188\/jea.JE20140132","article-title":"Relationship between decayed teeth and metabolic syndrome: data from 4716 middle-aged male Japanese employees","volume":"25","author":"Ojima","year":"2015","journal-title":"J Epidemiol"},{"key":"2024010504412054600_zwad295-B9","doi-asserted-by":"crossref","first-page":"3459","DOI":"10.1093\/eurheartj\/ehz646","article-title":"Causal association between periodontitis and hypertension: evidence from Mendelian randomization and a randomized controlled trial of non-surgical periodontal therapy","volume":"40","author":"Czesnikiewicz-Guzik","year":"2019","journal-title":"Eur Heart J"},{"key":"2024010504412054600_zwad295-B10","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/S2213-8587(18)30038-X","article-title":"Systemic effects of periodontitis treatment in patients with type 2 diabetes: a 12 month, single-centre, investigator-masked, randomised trial","volume":"6","author":"D'Aiuto","year":"2018","journal-title":"Lancet Diabetes Endocrinol"},{"key":"2024010504412054600_zwad295-B11","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1056\/NEJMoa063186","article-title":"Treatment of periodontitis and endothelial function","volume":"356","author":"Tonetti","year":"2007","journal-title":"N Engl J Med"},{"key":"2024010504412054600_zwad295-B12","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/prd.12299","article-title":"Periodontal therapy and cardiovascular risk","volume":"83","author":"Orlandi","year":"2020","journal-title":"Periodontol 2000"},{"key":"2024010504412054600_zwad295-B13","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1111\/prd.12302","article-title":"Periodontal diseases and association with atherosclerotic disease","volume":"83","author":"Herrera","year":"2020","journal-title":"Periodontol 2000"},{"key":"2024010504412054600_zwad295-B14","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/jcpe.13189","article-title":"Periodontitis and cardiovascular diseases: consensus report","volume":"47","author":"Sanz","year":"2020","journal-title":"J Clin Periodontol"},{"key":"2024010504412054600_zwad295-B15","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2022.1000478","article-title":"The association between denture use and cardiovascular diseases. The United States National Health and Nutrition Examination Survey 2009\u20132018","volume":"9","author":"Liang","year":"2023","journal-title":"Front Cardiovasc Med"},{"key":"2024010504412054600_zwad295-B16","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1186\/s12903-020-01084-9","article-title":"Number of natural teeth, denture use and mortality in Chinese elderly: a population-based prospective cohort study","volume":"20","author":"Yuan","year":"2020","journal-title":"BMC Oral Health"},{"key":"2024010504412054600_zwad295-B17","doi-asserted-by":"crossref","first-page":"6061","DOI":"10.1038\/s41598-021-85440-x","article-title":"Association between denture use, chewing ability, and all-cause mortality in middle-aged and older adults who exercised regularly in Korea","volume":"11","author":"Jang","year":"2021","journal-title":"Sci Rep"},{"key":"2024010504412054600_zwad295-B18","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1186\/s12903-021-01529-9","article-title":"Removable denture is a risk indicator for peri-implantitis and facilitates expansion of specific periodontopathogens: a cross-sectional study","volume":"21","author":"Grischke","year":"2021","journal-title":"BMC Oral Health"},{"key":"2024010504412054600_zwad295-B19","doi-asserted-by":"crossref","first-page":"k601","DOI":"10.1136\/bmj.k601","article-title":"Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians","volume":"362","author":"Davies","year":"2018","journal-title":"BMJ"},{"key":"2024010504412054600_zwad295-B20","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/s41586-018-0579-z","article-title":"The UK Biobank resource with deep phenotyping and genomic data","volume":"562","author":"Bycroft","year":"2018","journal-title":"Nature"},{"key":"2024010504412054600_zwad295-B21","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001779","article-title":"UK Biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age","volume":"12","author":"Sudlow","year":"2015","journal-title":"PLoS Med"},{"key":"2024010504412054600_zwad295-B22","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1093\/bioinformatics\/btq340","article-title":"METAL: fast and efficient meta-analysis of genomewide association scans","volume":"26","author":"Willer","year":"2010","journal-title":"Bioinformatics"},{"key":"2024010504412054600_zwad295-B23","doi-asserted-by":"crossref","first-page":"2773","DOI":"10.1038\/s41467-019-10630-1","article-title":"Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data","volume":"10","author":"Shungin","year":"2019","journal-title":"Nat Commun"},{"key":"2024010504412054600_zwad295-B24","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1038\/s41431-018-0265-5","article-title":"Meta-analysis of genome-wide association studies of aggressive and chronic periodontitis identifies two novel risk loci","volume":"27","author":"Munz","year":"2019","journal-title":"Eur J Hum Genet"},{"key":"2024010504412054600_zwad295-B25","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.1093\/hmg\/ddx151","article-title":"A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis","volume":"26","author":"Munz","year":"2017","journal-title":"Hum Mol Genet"},{"key":"2024010504412054600_zwad295-B26","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1038\/s41467-017-02317-2","article-title":"Causal associations between risk factors and common diseases inferred from GWAS summary data","volume":"9","author":"Zhu","year":"2018","journal-title":"Nat Commun"},{"key":"2024010504412054600_zwad295-B27","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/ng.3211","article-title":"LD score regression distinguishes confounding from polygenicity in genome-wide association studies","volume":"47","author":"Bulik-Sullivan","year":"2015","journal-title":"Nat Genet"},{"key":"2024010504412054600_zwad295-B28","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1002\/gepi.21965","article-title":"Consistent estimation in Mendelian randomization with some invalid instruments using a weighted median estimator","volume":"40","author":"Bowden","year":"2016","journal-title":"Genet Epidemiol"},{"key":"2024010504412054600_zwad295-B29","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1093\/ije\/dyv080","article-title":"Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression","volume":"44","author":"Bowden","year":"2015","journal-title":"Int J Epidemiol"},{"key":"2024010504412054600_zwad295-B30","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.2337\/dc19-0018","article-title":"Undetected dysglycemia is an important risk factor for two common diseases, myocardial infarction and periodontitis: a report from the PAROKRANK study","volume":"42","author":"Norhammar","year":"2019","journal-title":"Diabetes Care"},{"key":"2024010504412054600_zwad295-B31","doi-asserted-by":"crossref","first-page":"c2451","DOI":"10.1136\/bmj.c2451","article-title":"Toothbrushing, inflammation, and risk of cardiovascular disease: results from Scottish Health Survey","volume":"340","author":"de Oliveira","year":"2010","journal-title":"BMJ"},{"key":"2024010504412054600_zwad295-B32","doi-asserted-by":"crossref","first-page":"563","DOI":"10.2337\/dc19-1201","article-title":"Impact of treating oral disease on preventing vascular diseases: a model-based cost-effectiveness analysis of periodontal treatment among patients with type 2 diabetes","volume":"43","author":"Choi","year":"2020","journal-title":"Diabetes Care"},{"key":"2024010504412054600_zwad295-B33","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1177\/2047487319886018","article-title":"Improved oral hygiene care is associated with decreased risk of occurrence for atrial fibrillation and heart failure: a nationwide population-based cohort study","volume":"27","author":"Chang","year":"2020","journal-title":"Eur J Prev Cardiol"},{"key":"2024010504412054600_zwad295-B34","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1038\/s41431-020-00734-4","article-title":"Assessment and visualization of phenome-wide causal relationships using genetic data: an application to dental caries and periodontitis","volume":"29","author":"Haworth","year":"2021","journal-title":"Eur J Hum Genet"},{"key":"2024010504412054600_zwad295-B35","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3390\/genes13010013","article-title":"Causal association between periodontal diseases and cardiovascular diseases","volume":"13","author":"Zhou","year":"2021","journal-title":"Genes (Basel)"},{"key":"2024010504412054600_zwad295-B36","doi-asserted-by":"crossref","first-page":"792396","DOI":"10.3389\/fgene.2021.792396","article-title":"Causal association between periodontitis and type 2 diabetes: a bidirectional two-sample Mendelian randomization analysis","volume":"12","author":"Wang","year":"2022","journal-title":"Front Genet"},{"key":"2024010504412054600_zwad295-B37","doi-asserted-by":"crossref","first-page":"767577","DOI":"10.3389\/fgene.2021.767577","article-title":"Impact of liability to periodontitis on glycemic control and type II diabetes risk: a Mendelian randomization study","volume":"12","author":"Shah","year":"2021","journal-title":"Front Genet"},{"key":"2024010504412054600_zwad295-B38","doi-asserted-by":"crossref","first-page":"e2888","DOI":"10.1002\/brb3.2888","article-title":"Periodontitis and stroke: a Mendelian randomization study","volume":"13","author":"Ma","year":"2023","journal-title":"Brain Behav"},{"key":"2024010504412054600_zwad295-B39","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.atherosclerosis.2020.09.029","article-title":"Is periodontitis a risk factor for ischaemic stroke, coronary artery disease and subclinical atherosclerosis? A Mendelian randomization study","volume":"313","author":"Bell","year":"2020","journal-title":"Atherosclerosis"},{"key":"2024010504412054600_zwad295-B40","doi-asserted-by":"crossref","first-page":"3304","DOI":"10.1093\/eurheartj\/ehaa193","article-title":"Genetic predisposition to smoking in relation to 14 cardiovascular diseases","volume":"41","author":"Larsson","year":"2020","journal-title":"Eur Heart J"},{"key":"2024010504412054600_zwad295-B41","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1093\/eurheartj\/ehz388","article-title":"Body mass index and body composition in relation to 14 cardiovascular conditions in UK Biobank: a Mendelian randomization study","volume":"41","author":"Larsson","year":"2020","journal-title":"Eur Heart J"},{"key":"2024010504412054600_zwad295-B42","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1038\/sj.bdj.2012.1088","article-title":"Adult Dental Health Survey 2009: common oral health conditions and their impact on the population","volume":"213","author":"White","year":"2012","journal-title":"Br Dent J"},{"key":"2024010504412054600_zwad295-B43","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1308\/205016817822230175","article-title":"Denture stomatitis: causes, cures and prevention","volume":"6","author":"Hannah","year":"2017","journal-title":"Prim Dent J"},{"key":"2024010504412054600_zwad295-B44","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1093\/ije\/dyv075","article-title":"Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium","volume":"44","author":"Shungin","year":"2015","journal-title":"Int J Epidemiol"},{"key":"2024010504412054600_zwad295-B45","doi-asserted-by":"crossref","first-page":"2898","DOI":"10.3390\/nu11122898","article-title":"Poor oral health as a determinant of malnutrition and sarcopenia","volume":"11","author":"Azzolino","year":"2019","journal-title":"Nutrients"},{"key":"2024010504412054600_zwad295-B46","doi-asserted-by":"crossref","first-page":"197","DOI":"10.3390\/jcm10020197","article-title":"Nutrition as a key modifiable factor for periodontitis and main chronic diseases","volume":"10","author":"Martinon","year":"2021","journal-title":"J Clin Med"},{"key":"2024010504412054600_zwad295-B47","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1111\/jcpe.13484","article-title":"Diagnostic accuracy of self-reported measures of periodontal disease: a clinical validation study using the 2017 case definitions","volume":"48","author":"Deng","year":"2021","journal-title":"J Clin Periodontol"},{"key":"2024010504412054600_zwad295-B48","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1111\/jcpe.13351","article-title":"Self-reported bleeding on brushing as a predictor of bleeding on probing: early observations from the deployment of an internet of things network of intelligent power-driven toothbrushes in a supportive periodontal care population","volume":"47","author":"Tonetti","year":"2020","journal-title":"J Clin Periodontol"},{"key":"2024010504412054600_zwad295-B49","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1902\/jop.2016.160196","article-title":"Validity of self-reported periodontal disease: a systematic review and meta-analysis","volume":"87","author":"Abbood","year":"2016","journal-title":"J Periodontol"}],"container-title":["European Journal of Preventive Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/eurjpc\/advance-article-pdf\/doi\/10.1093\/eurjpc\/zwad295\/51894984\/zwad295.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurjpc\/article-pdf\/31\/1\/13\/54908349\/zwad295.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurjpc\/article-pdf\/31\/1\/13\/54908349\/zwad295.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T23:57:41Z","timestamp":1704412661000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurjpc\/article\/31\/1\/13\/7269174"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,11]]},"references-count":49,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,9,11]]},"published-print":{"date-parts":[[2024,1,5]]}},"URL":"https:\/\/doi.org\/10.1093\/eurjpc\/zwad295","relation":{},"ISSN":["2047-4873","2047-4881"],"issn-type":[{"value":"2047-4873","type":"print"},{"value":"2047-4881","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,1]]},"published":{"date-parts":[[2023,9,11]]}}}