{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T03:48:37Z","timestamp":1782964117394,"version":"3.54.5"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T00:00:00Z","timestamp":1700697600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Dr. B.Gencer Foundation","award":["SNSF 32003B_207881"],"award-info":[{"award-number":["SNSF 32003B_207881"]}]},{"DOI":"10.13039\/501100004362","name":"Swiss Heart Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004362","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001711","name":"Swiss National Science Foundation","doi-asserted-by":"publisher","award":["SPUM 33CM30-124112"],"award-info":[{"award-number":["SPUM 33CM30-124112"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001711","name":"Swiss National Science Foundation","doi-asserted-by":"publisher","award":["32473B_163271"],"award-info":[{"award-number":["32473B_163271"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001711","name":"Swiss National Science Foundation","doi-asserted-by":"publisher","award":["SNSF 325130_204361"],"award-info":[{"award-number":["SNSF 325130_204361"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007555","name":"Foundation for Cardiovascular Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007555","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016545","name":"Roche Diagnostics","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016545","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Eli Lilly"},{"name":"AstraZeneca Baar"},{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Merck Sharpe and Dome"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>To evaluate the risk of alcohol consumption after acute coronary syndromes (ACS).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>A total of 6557 patients hospitalized for ACS at four Swiss centres were followed over 12 months. Weekly alcohol consumption was collected at baseline and 12 months. Binge drinking was defined as consumption of \u22656 units of alcohol on one occasion. Major adverse cardiovascular events (MACE) were defined as a composite of cardiac death, myocardial infarction, stroke, or clinically indicated target vessel coronary revascularization. Cox regression analysis was performed to assess the risk of MACE in patients with heavy (&amp;gt;14 standard units\/week), moderate (7\u201314 standard units per week), light consumption (&amp;lt;1 standard unit\/week), or abstinence, and with binge drinking episodes, adjusted for baseline differences. At baseline, 817 (13.4%) patients reported heavy weekly alcohol consumption. At 1-year follow-up, 695\/1667 (41.6%) patients reported having at least one or more episodes of binge drinking per month. The risk for MACE was not significantly higher in those with heavy weekly consumption compared to abstinence [8.6% vs. 10.2%, hazard ratio (HR) 0.97, 95% confidence interval (CI) 0.69\u20131.36] or light consumption (8.6% vs. 8.5%, HR 1.41, 95% CI 0.97\u20132.06). Compared to patients with no binge drinking, the risk of MACE was dose-dependently higher in those with binge drinking with less than one episode per month (9.2% vs. 7.8%, HR 1.61, 95% CI 1.23\u20132.11) or one or more episodes per month (13.6% vs. 7.8%, HR 2.17, 95% CI 1.66\u20132.83).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Binge drinking during the year following an ACS, even less than once per month, is associated with worse clinical outcomes.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/eurjpc\/zwad364","type":"journal-article","created":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T01:09:54Z","timestamp":1700701794000},"page":"845-855","source":"Crossref","is-referenced-by-count":11,"title":["Drinking patterns of alcohol and risk of major adverse cardiovascular events after an acute coronary syndrome"],"prefix":"10.1093","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1680-0152","authenticated-orcid":false,"given":"Elena","family":"Tessitore","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Geneva University Hospitals , Rue Gabrielle Perret-Gentil 4, 1205 Geneva , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mattia","family":"Branca","sequence":"additional","affiliation":[{"name":"Clinical Trial Unit, University of Bern , Bern , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8766-7945","authenticated-orcid":false,"given":"Dik","family":"Heg","sequence":"additional","affiliation":[{"name":"Clinical Trial Unit, University of Bern , Bern , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Nanchen","sequence":"additional","affiliation":[{"name":"Department of Health Promotion and Preventions, Center for Primary Care and Public Health (Unisant\u00e9), University of Lausanne , Lausanne , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reto","family":"Auer","sequence":"additional","affiliation":[{"name":"Department of Health Promotion and Preventions, Center for Primary Care and Public Health (Unisant\u00e9), University of Lausanne , Lausanne , Switzerland"},{"name":"Institute of Primary Health Care (BIHAM), University of Bern , Mittelstrasse 43, 3012 Bern , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0824-3026","authenticated-orcid":false,"given":"Lorenz","family":"R\u00e4ber","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Bern University Hospital, University of Bern , Bern , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7726-4421","authenticated-orcid":false,"given":"Roland","family":"Klingenberg","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital of Zurich , Zurich , Switzerland"},{"name":"Department of Cardiology, Kerckhoff Heart and Thorax Center, Campus of the Justus Liebig University of Giessen , Bad Nauheim , Germany"},{"name":"DZHK (German Center for Cardiovascular Research), partner site Rhine-Main , Bad Nauheim , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2653-6762","authenticated-orcid":false,"given":"Stephan","family":"Windecker","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Bern University Hospital, University of Bern , Bern , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas F","family":"L\u00fcscher","sequence":"additional","affiliation":[{"name":"Royal Brompton & Harefield Hospitals GSTT, Imperial College and Kings College , London , UK"},{"name":"Center for Molecular Cardiology, Schlieren Campus, University Zurich , Zurich , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Carballo","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine, Department of Internal Medicine, Rehabilitation and Geriatrics, Geneva University Hospitals , Geneva , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian M","family":"Matter","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital of Zurich , Zurich , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerhard","family":"Gmel","sequence":"additional","affiliation":[{"name":"Addiction Medicine, Lausanne University Hospital and University of Lausanne , Lausanne , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth J","family":"Mukamal","sequence":"additional","affiliation":[{"name":"Beth Israel Deaconess Medical Center, Harvard Medical School , Boston, MA , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9083-6896","authenticated-orcid":false,"given":"Nicolas","family":"Rodondi","sequence":"additional","affiliation":[{"name":"Institute of Primary Health Care (BIHAM), University of Bern , Mittelstrasse 43, 3012 Bern , Switzerland"},{"name":"Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern , Bern , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3212-1272","authenticated-orcid":false,"given":"David","family":"Carballo","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Geneva University 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