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Development","doi-asserted-by":"publisher","award":["JP23dk0207053"],"award-info":[{"award-number":["JP23dk0207053"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP23km0405209"],"award-info":[{"award-number":["JP23km0405209"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JPMJPF2210"],"award-info":[{"award-number":["JPMJPF2210"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Several prospective studies have reported that higher visit-to-visit blood pressure variability (BPV) is associated with atrial fibrillation (AF). However, no studies have investigated the association between day-to-day BPV assessed by home blood pressure measurement and the development of AF.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>A total of 2829 community-dwelling Japanese aged \u226540 years without prior AF were followed up for 10 years (2007\u201317). Day-to-day home BPV [defined as coefficient of variation (CoV) of home systolic blood pressure (SBP) for 28 days] was categorized into four groups according to the quartiles: Q1, \u2264 4.64%; Q2, 4.65\u20135.70%; Q3, 5.71\u20137.01%; Q4, \u2265 7.02%. The hazard ratios for developing AF were estimated using a Cox proportional hazards model. During the follow-up period, 134 participants developed new-onset AF. The crude incidence rates of AF increased significantly with higher CoV levels of home SBP: 2.1, 4.9, 5.2, and 8.8 per 1000 person-years in the first, second, third, and fourth quartiles, respectively (P for trend &amp;lt; 0.01). After adjusting for potential confounders, increased CoV levels of home SBP were associated significantly with a higher risk of AF (P for trend = 0.02). The participants in the highest quartile of CoV had a 2.20-fold (95% confidence intervals: 1.18\u20134.08) increased risk of developing AF compared with those in the lowest quartile.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>The present findings suggest that increased day-to-day home BPV levels are associated with a higher risk of the development of AF in a general Japanese population.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/eurjpc\/zwae035","type":"journal-article","created":{"date-parts":[[2024,1,29]],"date-time":"2024-01-29T13:37:26Z","timestamp":1706535446000},"page":"1115-1122","source":"Crossref","is-referenced-by-count":7,"title":["Day-to-day home blood pressure variability and risk of atrial fibrillation in a general Japanese population: the Hisayama 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Medical Sciences, Kyushu University , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 ,","place":["Japan"]},{"name":"Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Hata","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Public Health, Graduate School of Medical Sciences, Kyushu University , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 ,","place":["Japan"]},{"name":"Center for Cohort Studies, Graduate School of Medical Sciences, Kyushu University , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 ,","place":["Japan"]},{"name":"Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emi","family":"Oishi","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Public Health, Graduate School of Medical Sciences, Kyushu University , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 ,","place":["Japan"]},{"name":"Center for Cohort Studies, Graduate School of Medical Sciences, Kyushu University , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 ,","place":["Japan"]},{"name":"Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiko","family":"Furuta","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Public Health, Graduate School of Medical Sciences, Kyushu University , 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582 ,","place":["Japan"]},{"name":"Department of 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