{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:04:45Z","timestamp":1792785885024,"version":"4.5.0"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2024,2,27]],"date-time":"2024-02-27T00:00:00Z","timestamp":1708992000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Charity Cardiac Risk in the Young"},{"name":"Charity Cardiac Risk in the Young"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>There is limited information on the clinical significance of complete right bundle branch block (CRBBB) in young individuals. The aim of this study was to determine the prevalence and significance of CRBBB in a large cohort of young individuals aged 14\u201335 years old.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>From 2008 to 2018, 104,369 consecutive individuals underwent cardiovascular assessment with a health questionnaire, electrocardiogram, clinical consultation, and selective echocardiography. Follow-up was obtained via direct telephone consultations. Mean follow-up was 7.3 \u00b1 2.7 years. CRBBB was identified in 154 (0.1%) individuals and was more prevalent in males compared with females (0.20 vs. 0.06%; P &amp;lt; 0.05) and in athletes compared with non-athletes (0.25 vs. 0.14%; P &amp;lt; 0.05). CRBBB-related cardiac conditions were identified in seven (5%) individuals (four with atrial septal defect, one with Brugada syndrome, one with progressive cardiac conduction disease, and one with atrial fibrillation). Pathology was more frequently identified in individuals with non-isolated CRBBB compared with individuals with isolated CRBBB (14 vs. 1%; P &amp;lt; 0.05) and in individuals with a QRS duration of \u2265130 ms compared with individuals with a QRS of &amp;lt;130 ms (10 vs. 1%; P &amp;lt; 0.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The prevalence of CRBBB in young individuals was 0.1% and was more prevalent in males and in athletes. CRBBB-related conditions were identified in 5% of individuals and were more common in individuals with non-isolated CRBBB and more pronounced intraventricular conduction delay (QRS duration of \u2265130\u2005ms). Secondary evaluation should be considered for young individuals with CRBBB with symptoms, concerning family history, additional electrocardiographic anomalies, or significant QRS prolongation (\u2265130\u2005ms).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/eurjpc\/zwae082","type":"journal-article","created":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T01:15:14Z","timestamp":1708910114000},"page":"1054-1061","source":"Crossref","is-referenced-by-count":9,"title":["Prevalence and clinical significance of electrocardiographic complete right bundle branch block in young individuals"],"prefix":"10.1093","volume":"32","author":[{"given":"Hamish","family":"MacLachlan","sequence":"first","affiliation":[{"name":"St George's, University of London , London SW17 0RE ,","place":["UK"]},{"name":"St George's University Hospitals NHS Foundation Trust , Blackshaw Rd, London SW17 0QT 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,","place":["UK"]},{"name":"St George's University Hospitals NHS Foundation Trust , Blackshaw Rd, London SW17 0QT ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1339-665X","authenticated-orcid":false,"given":"Joyee","family":"Basu","sequence":"additional","affiliation":[{"name":"St George's, University of London , London SW17 0RE ,","place":["UK"]},{"name":"St George's University Hospitals NHS Foundation Trust , Blackshaw Rd, London SW17 0QT ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8192-5739","authenticated-orcid":false,"given":"Chris","family":"Miles","sequence":"additional","affiliation":[{"name":"St George's, University of London , London SW17 0RE ,","place":["UK"]},{"name":"St George's University Hospitals NHS Foundation Trust , Blackshaw Rd, London SW17 0QT 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Cardiology, Frimley Park Hospital , London ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nabeel","family":"Sheikh","sequence":"additional","affiliation":[{"name":"St George's, University of London , London SW17 0RE ,","place":["UK"]},{"name":"St George's University Hospitals NHS Foundation Trust , Blackshaw Rd, London SW17 0QT ,","place":["UK"]},{"name":"Department of Cardiology, Guy\u2019s and St Thomas\u2019s Hospital , London ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0199-5092","authenticated-orcid":false,"given":"Sabiha","family":"Gati","sequence":"additional","affiliation":[{"name":"St George's, University of London , London SW17 0RE ,","place":["UK"]},{"name":"St George's University Hospitals NHS Foundation Trust , Blackshaw Rd, London SW17 0QT ,","place":["UK"]},{"name":"Department of Cardiology, Royal Brompton and Harefield NHS Foundation Trust , London 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