{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T15:24:31Z","timestamp":1781796271061,"version":"3.54.5"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T00:00:00Z","timestamp":1732665600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32200895"],"award-info":[{"award-number":["32200895"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,4,22]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Type D personality has been established as an independent psychological risk factor for adverse outcomes in coronary artery disease (CAD) patients. However, research on the association between Type D personality and cardiovascular events in couples is limited. This study investigated the correlation between Type D personality and cardiovascular outcomes among CAD patients and their spouses.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>This prospective cohort study included 4035 CAD patients for first coronary intervention therapy and their spouses, recruited from January 2017 to July 2020. Type D personality, anxiety, depression, and baseline clinical data were assessed for both partners. The major adverse cardiac event (MACE) rate of both CAD patients and their spouses was analysed after a 3-year follow-up period. A total of 871 CAD patients and 234 spouses developed MACE during the follow-up period. The Cox proportional hazards regression analysis revealed that the Type D(+) patient\/Type D(+) spouse group exhibited the highest risk of 3-year MACE in both patients [hazard ratio (HR), 3.834; 95% confidence interval (CI), 2.947\u20134.987; P &amp;lt; 0.001) and spouses (HR, 2.670; 95% CI, 1.603\u20134.448; P &amp;lt; 0.001). When analysing Type D as continuous variables, a synergistic interaction between patient and spouse negative affectivity (NA_patient \u00d7 NA_spouse) was significantly associated with MACE in both CAD patients (HR, 1.746; 95% CI, 1.517\u20132.010; P &amp;lt; 0.001) and their spouses (HR, 1.992; 95% CI, 1.843\u20132.152; P &amp;lt; 0.001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>This study suggests that having Type D personality, either in the CAD patient or their spouse, is associated with an increased risk of adverse cardiovascular outcomes in both individuals. Accordingly, the assessment of Type D personality in both partners and the development of tailored, couple-centred interventions are warranted.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/eurjpc\/zwae377","type":"journal-article","created":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T18:54:07Z","timestamp":1732733647000},"page":"430-440","source":"Crossref","is-referenced-by-count":12,"title":["Type D personality as a risk factor for 3-year cardiovascular events in patients with coronary artery disease and their spouse: a prospective cohort study"],"prefix":"10.1093","volume":"32","author":[{"given":"Yini","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University , No. 246 Xuefu Road, Nangang District, Harbin 150081, Heilongjiang Province ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingji","family":"Huang","sequence":"additional","affiliation":[{"name":"College of Nursing, Harbin Medical University , No. 157, Baojian Road, Nangang District, Harbin 150081, Heilongjiang Province ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengru","family":"Sun","sequence":"additional","affiliation":[{"name":"College of Nursing, Harbin Medical University , No. 157, Baojian Road, Nangang District, Harbin 150081, Heilongjiang Province ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University , No. 246 Xuefu Road, Nangang District, Harbin 150081, Heilongjiang Province 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