{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T02:27:07Z","timestamp":1783736827684,"version":"3.55.0"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T00:00:00Z","timestamp":1741132800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,22]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study aims to compare the effect of moderate-intensity continuous training (MICT) vs. isovolumic high-intensity interval training (HIIT) on left ventricular (LV) myocardial function early post-acute myocardial infarction (AMI). Training-induced changes were analysed at both global and segmental levels using advanced deformation echocardiographic imaging techniques.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>One hundred AMI patients were randomly assigned to participate in an 8-week training programme comprising either MICT (n = 50) or isovolumic HIIT (n = 50), starting within 6 weeks post-AMI. Before and after cardiac rehabilitation (CR), we carried out a comprehensive and detailed evaluation of myocardial function, including measurements of LV longitudinal strain (LS) and circumferential strain and torsional mechanics, LV myocardial work (MW) and mechanical dispersion [post-systolic shortenings (PSS)] indexes, and atrial strains. Mixed models were used to evaluate the effect of MICT and HIIT on speckle-tracking echocardiography parameter. Both MICT and HIIT resulted in a similar improvement in the amplitude and timing of LV LS (time effect P &amp;lt; 0.001 in each case), as depicted by the comparable increase in global LS [HIIT: \u22120.82%, 95% confidence interval (CI): \u22120.19\/\u221261; MICT: \u22121.11%, 95% CI: \u22121.17\/\u22120.51; time \u2217 group P = 0.71], MW index and efficiency, constructive MW, and reduction in the number of PSS and wasted MW (time \u2217 group P &amp;gt; 0.12 in each case) in the two groups. These improvements were observed in all myocardial territories, regardless of previous ischaemic risk status (culprit vessel-by-time-by-group interactions, P &amp;gt; 0.60 in each case). Circumferential strains remained unchanged in both groups while there was a trend (time \u2217 group P = 0.04) for LV torsion to decrease for MICT (P = 0.06) and increase for HIIT (P = 0.36) after CR. Left atrial strains during the reservoir and conduit phases improved (time effect P &amp;lt; 0.05) similarly in MICT vs. HIIT (time \u2217 group P &amp;gt; 0.54). V\u0307O2peak (P &amp;lt; 0.001) and quality of life (P &amp;lt; 0.001) improved equally in MICT and HIIT after CR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Early supervised exercise-based CR, whether using MICT or isovolumic HIIT, improves longitudinal myocardial function in both culprit and non-culprit territories after AMI.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/eurjpc\/zwaf127","type":"journal-article","created":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T15:24:31Z","timestamp":1741015471000},"page":"883-894","source":"Crossref","is-referenced-by-count":3,"title":["A comprehensive analysis of the impact of high-intensity interval vs. moderate-intensity continuous training on global and regional myocardial function in patients early after acute myocardial infarction: the STRAICT randomized controlled trial"],"prefix":"10.1093","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0472-6338","authenticated-orcid":false,"given":"Philippe","family":"Obert","sequence":"first","affiliation":[{"name":"Avignon Universit\u00e9, LAPEC, UPR 4278, Avignon ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Nottin","sequence":"additional","affiliation":[{"name":"Avignon Universit\u00e9, LAPEC, UPR 4278, Avignon ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clarisse","family":"Belvisi","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, CHU N\u00eemes, Montpellier Universit\u00e9 , N\u00eemes ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christelle","family":"Robert","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, CHU N\u00eemes, Montpellier Universit\u00e9 , N\u00eemes ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Miramont","sequence":"additional","affiliation":[{"name":"Clinique Lavarin, CLINEA , Avignon ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"de France","sequence":"additional","affiliation":[{"name":"Clinique Lavarin, CLINEA , Avignon ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roland","family":"Carlioz","sequence":"additional","affiliation":[{"name":"Clinique Lavarin, CLINEA , Avignon ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Fran\u00e7ois","family":"Landrier","sequence":"additional","affiliation":[{"name":"Aix-Marseille Universit\u00e9, INRAE, INSERM , C2VN Marseille ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Poirier","sequence":"additional","affiliation":[{"name":"Institut Universitaire de Cardiologie et de Pneumologie de Qu\u00e9bec, Universit\u00e9 Laval , Qu\u00e9bec, QC ,","place":["Canada"]},{"name":"Faculty of Pharmacy, Universit\u00e9 Laval , Qu\u00e9bec, QC ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaud","family":"Dupeyron","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, CHU N\u00eemes, Montpellier Universit\u00e9 , N\u00eemes ,","place":["France"]},{"name":"EuroMov Digital Health in Motion, Montpellier Universit\u00e9, IMT Mines Ales , Montpellier ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,3,5]]},"reference":[{"key":"2026042119575754800_zwaf127-B1","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1093\/eurjpc\/zwab007","article-title":"Exercise intensity assessment and prescription in cardiovascular rehabilitation and beyond: why and how. 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