{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T23:47:06Z","timestamp":1793317626894,"version":"4.5.0"},"reference-count":60,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T00:00:00Z","timestamp":1742860800000},"content-version":"am","delay-in-days":18,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Asymptomatic atrial fibrillation (AF) is frequent and associated with disease progression. This meta-analysis aimed to estimate the prevalence of asymptomatic AF and identify risk factors associated with asymptomatic status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>MEDLINE (PubMed), Scopus, Cochrane, and ClinicalTrials.gov were searched until 8 January 2025. Double-independent study selection, data extraction, and quality assessments were performed. Random-effects meta-analysis was used. Estimates are presented with the asymptomatic individuals in the nominator and the symptomatic patients in the denominator. The assessment of the prevalence of asymptomatic AF and the identification of risk factors associated with the asymptomatic status comprised the main endpoints. Thirty-seven studies (224 273 participants) were included. The prevalence of asymptomatic AF was 27% [95% confidence interval (CI) = (22%, 33%); I2 = 100%]. Risk factors positively associated with the asymptomatic status were male sex [odds ratio (OR)=1.67, 95% CI = (1.48, 1.89), P &amp;lt; 0.001, I2 = 85%), diabetes mellitus [OR = 1.19, 95% CI = (1.07, 1.33), P = 0.002, I2 = 87%], chronic kidney disease [OR = 1.21, 95% CI = (1.08, 1.36), P &amp;lt; 0.001, I2 = 80%] and stroke\/transient ischemic attack [OR = 1.43, 95% CI = (1.18, 1.73), P &amp;lt; 0.001, I2 = 95%], while heart failure was negatively associated with asymptomatic AF [OR = 0.71, 95% CI = (0.54, 0.94), P = 0.017, I2 = 97%]. Asymptomatic status was also positively associated with permanent AF [OR = 2.13, 95% CI = (1.28, 3.55); P = 0.004; I2 = 98%] and negatively associated with catheter ablation [OR = 0.63, 95% CI = (0.44, 0.91); P = 0.012; I2 = 95%], beta-blockers [OR = 0.90, 95% CI = (0.82, 0.98); P = 0.018; I2 = 68%] and antiarrhythmics [OR = 0.53, 95% CI = (0.35, 0.79); P = 0.002; I2 = 95%].<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Asymptomatic AF was estimated at around 27%, with large variability depending on the prevalence of risk factors associated with asymptomatic status. Asymptomatic individuals had distinct characteristics compared with symptomatic patients, regardless of symptoms\u2019 assessment methods and rhythm\/rate control interventions. Our results could inform AF screening practices to target asymptomatic individuals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Registration<\/jats:title>\n                    <jats:p>PROSPERO: CRD42024578738.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/eurjpc\/zwaf138","type":"journal-article","created":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T15:26:07Z","timestamp":1741274767000},"source":"Crossref","is-referenced-by-count":34,"title":["Prevalence of asymptomatic atrial fibrillation and risk factors associated with asymptomatic status: a systematic review and meta-analysis"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5411-6461","authenticated-orcid":false,"given":"Konstantinos","family":"Pamporis","sequence":"first","affiliation":[{"name":"First Cardiology Clinic, National and Kapodistrian University of Athens, School of Medicine, Hippokration General Hospital , Vasilissis Sofias 114, Athens 11528 ,","place":["Greece"]},{"name":"Department of Hygiene, Social-Preventive Medicine and Medical Statistics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, University Campus , Thessaloniki 54124 ,","place":["Greece"]},{"name":"Department of Pharmacology, Medical School, National and Kapodistrian University of Athens , Athens ,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3561-5713","authenticated-orcid":false,"given":"Paschalis","family":"Karakasis","sequence":"additional","affiliation":[{"name":"Department of Hygiene, Social-Preventive Medicine and Medical Statistics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, University Campus , Thessaloniki 54124 ,","place":["Greece"]},{"name":"Second Cardiology Department, Hippokration General Hospital, Medical School, Aristotle University of Thessaloniki , Thessaloniki ,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3473-1368","authenticated-orcid":false,"given":"Marios","family":"Sagris","sequence":"additional","affiliation":[{"name":"First Cardiology Clinic, National and Kapodistrian University of Athens, School of Medicine, Hippokration General Hospital , Vasilissis Sofias 114, Athens 11528 ,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9260-6306","authenticated-orcid":false,"given":"Panagiotis","family":"Theofilis","sequence":"additional","affiliation":[{"name":"First Cardiology Clinic, National and Kapodistrian University of Athens, School of Medicine, Hippokration General Hospital , Vasilissis Sofias 114, Athens 11528 ,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7312-0976","authenticated-orcid":false,"given":"Nikias","family":"Milaras","sequence":"additional","affiliation":[{"name":"First Cardiology Clinic, National and Kapodistrian University of Athens, School of Medicine, Hippokration General Hospital , Vasilissis Sofias 114, Athens 11528 ,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonia","family":"Pantelidaki","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Medical School, National and Kapodistrian University of Athens , Athens ,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9670-5886","authenticated-orcid":false,"given":"Iordanis","family":"Mourouzis","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Medical School, National and Kapodistrian University of Athens , Athens ,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7158-4950","authenticated-orcid":false,"given":"Nikolaos","family":"Fragakis","sequence":"additional","affiliation":[{"name":"Second Cardiology Department, Hippokration General Hospital, Medical School, Aristotle University of Thessaloniki , Thessaloniki ,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7543-3236","authenticated-orcid":false,"given":"Konstantinos","family":"Vlachos","sequence":"additional","affiliation":[{"name":"IHU Liryc, Univ. Bordeaux, INSERM, CRCTB , Bordeaux U 1045 ,","place":["France"]},{"name":"Cardiac Arrhythmia Department, CHU de Bordeaux, INSERM , Bordeaux U 1045 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athanasios","family":"Kordalis","sequence":"additional","affiliation":[{"name":"First Cardiology Clinic, National and Kapodistrian University of Athens, School of Medicine, Hippokration General Hospital , Vasilissis Sofias 114, Athens 11528 ,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Tsiachris","sequence":"additional","affiliation":[{"name":"First Cardiology Clinic, National and Kapodistrian University of Athens, School of Medicine, Hippokration General Hospital , Vasilissis Sofias 114, Athens 11528 ,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,3,7]]},"reference":[{"key":"2025032522412114100_zwaf138-B1","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1161\/CIRCRESAHA.120.316340","article-title":"Epidemiology of atrial fibrillation in the 21st century: novel methods and new insights","volume":"127","author":"Kornej","year":"2020","journal-title":"Circ Res"},{"key":"2025032522412114100_zwaf138-B2","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1093\/ehjqcco\/qcaa093","article-title":"Atrial fibrillation in the UK: predicting costs of an emerging epidemic recognizing and forecasting the cost drivers of atrial fibrillation-related costs","volume":"8","author":"Burdett","year":"2022","journal-title":"Eur Hear J Q Care Clin Outcomes"},{"key":"2025032522412114100_zwaf138-B3","doi-asserted-by":"crossref","first-page":"20163","DOI":"10.1161\/JAHA.120.020163","article-title":"Trends in cardiovascular mortality related to atrial fibrillation in the United States, 2011 to 2018","volume":"10","author":"Tanaka","year":"2021","journal-title":"J Am Heart Assoc"},{"key":"2025032522412114100_zwaf138-B4","doi-asserted-by":"crossref","first-page":"100157","DOI":"10.1016\/j.lanepe.2021.100157","article-title":"Atrial fibrillation epidemiology, disparity and healthcare contacts: a population-wide study of 5.6 million individuals","volume":"7","author":"Chung","year":"2021","journal-title":"Lancet Reg Heal\u2014Eur"},{"key":"2025032522412114100_zwaf138-B5","first-page":"1321","article-title":"Health care resource utilization and costs associated with atrial fibrillation and rural-urban disparities","volume":"28","author":"Jiang","year":"2022","journal-title":"J Manag Care Spec Pharm"},{"key":"2025032522412114100_zwaf138-B6","doi-asserted-by":"crossref","first-page":"3314","DOI":"10.1093\/eurheartj\/ehae176","article-title":"2024 ESC guidelines for the management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)","volume":"45","author":"Van Gelder","year":"2024","journal-title":"Eur Heart J"},{"key":"2025032522412114100_zwaf138-B7","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.amjmed.2014.11.026","article-title":"Asymptomatic atrial fibrillation: clinical correlates, management, and outcomes in the EORP-AF pilot general registry","volume":"128","author":"Boriani","year":"2015","journal-title":"Am J Med"},{"key":"2025032522412114100_zwaf138-B8","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.3390\/jcm10051091","article-title":"Symptomatic and asymptomatic patients in the Polish atrial fibrillation (POL-AF) registry","volume":"10","author":"Kiliszek","year":"2021","journal-title":"J Clin Med"},{"key":"2025032522412114100_zwaf138-B9","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1093\/europace\/eut395","article-title":"The European Heart Rhythm Association symptom classification for atrial fibrillation: validation and improvement through a simple modification","volume":"16","author":"Wynn","year":"2014","journal-title":"Europace"},{"key":"2025032522412114100_zwaf138-B10","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.ijcard.2015.03.122","article-title":"Asymptomatic\u201d persistent or permanent atrial fibrillation: a misnomer in selected patients","volume":"185","author":"Ganapathy","year":"2015","journal-title":"Int J Cardiol"},{"key":"2025032522412114100_zwaf138-B11","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehae694","article-title":"Major clinical outcomes in symptomatic vs. asymptomatic atrial fibrillation: a meta-analysis","author":"Karakasis","year":"2024","journal-title":"Eur Heart J"},{"key":"2025032522412114100_zwaf138-B12","doi-asserted-by":"crossref","first-page":"3979","DOI":"10.3390\/jcm10173979","article-title":"Comparing outcomes in asymptomatic and symptomatic atrial fibrillation: a systematic review and meta-analysis of 81,462 patients","volume":"10","author":"Sgreccia","year":"2021","journal-title":"J Clin Med"},{"key":"2025032522412114100_zwaf138-B13","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1253\/circj.CJ-13-1272","article-title":"Progression to the persistent form in asymptomatic paroxysmal atrial fibrillation","volume":"78","author":"Senoo","year":"2014","journal-title":"Circ J"},{"key":"2025032522412114100_zwaf138-B14","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1016\/j.jacep.2024.03.006","article-title":"Rhythm vs rate control strategy for atrial fibrillation: a meta-analysis of randomized controlled trials","volume":"10","author":"Zafeiropoulos","year":"2024","journal-title":"JACC Clin Electrophysiol"},{"key":"2025032522412114100_zwaf138-B15","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1001\/jama.2022.5207","article-title":"Screening for atrial fibrillation: US preventive services task force recommendation statement","volume":"327","author":"Davidson","year":"2022","journal-title":"JAMA"},{"key":"2025032522412114100_zwaf138-B16","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1161\/CIR.0000000000001193","article-title":"2023 ACC\/AHA\/ACCP\/HRS guideline for the diagnosis and management of atrial fibrillation: a report of the American College of Cardiology\/American Heart Association joint committee on clinical practice guidelines","volume":"149","author":"Joglar","year":"2024","journal-title":"Circulation"},{"key":"2025032522412114100_zwaf138-B17","author":"Higgins"},{"key":"2025032522412114100_zwaf138-B18","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"2025032522412114100_zwaf138-B19","unstructured":"Haddaway NR, Grainger MJ, Gray CT. \u00a0citationchaser: An R package and Shiny app for forward and backward citations chasing in academic searching 2021. 10.5281\/ZENODO.4543513"},{"key":"2025032522412114100_zwaf138-B20"},{"key":"2025032522412114100_zwaf138-B21","volume-title":"Cochrane Handbook for Systematic Reviews of Interventions version 6.5","author":"Deeks","year":"2024"},{"key":"2025032522412114100_zwaf138-B22","doi-asserted-by":"crossref","first-page":"251","DOI":"10.14797\/mdcj-14-4-251","article-title":"Cardiac autonomic neuropathy in diabetes Mellitus","volume":"14","author":"Agashe","year":"2018","journal-title":"Methodist Debakey Cardiovasc J"},{"key":"2025032522412114100_zwaf138-B23","doi-asserted-by":"crossref","first-page":"108802","DOI":"10.1016\/j.jdiacomp.2024.108802","article-title":"The association of diabetic peripheral neuropathy with cardiac autonomic neuropathy in individuals with diabetes mellitus: a systematic review","volume":"38","author":"de Paula","year":"2024","journal-title":"J Diabetes Complications"},{"key":"2025032522412114100_zwaf138-B24","first-page":"204800401667768","article-title":"Neurological complications in chronic kidney disease","volume":"5","author":"Arnold","year":"2016","journal-title":"JRSM Cardiovasc Dis"},{"key":"2025032522412114100_zwaf138-B25","doi-asserted-by":"crossref","first-page":"4744","DOI":"10.1016\/j.ijcard.2013.07.234","article-title":"A comparison of clinical characteristics and long-term prognosis in asymptomatic and symptomatic patients with first-diagnosed atrial fibrillation: the Belgrade atrial fibrillation study","volume":"168","author":"Potpara","year":"2013","journal-title":"Int J Cardiol"},{"key":"2025032522412114100_zwaf138-B26","doi-asserted-by":"crossref","first-page":"100967","DOI":"10.1016\/j.lanepe.2024.100967","article-title":"Comparing CHA 2 DS 2-VA and CHA 2 DS 2-VASc scores for stroke risk stratification in patients with atrial fibrillation: a temporal trends analysis from the retrospective Finnish AntiCoagulation in atrial fibrillation (FinACAF) cohort 2024","volume":"43","author":"Teppo","year":"2024","journal-title":"Lancet Reg Health Eur"},{"key":"2025032522412114100_zwaf138-B27","doi-asserted-by":"crossref","first-page":"oeae061","DOI":"10.1093\/ehjopen\/oeae061","article-title":"The incidence of atrial fibrillation detected by implantable loop recorders: a comparison between patients with and without embolic stroke of undetermined source","volume":"4","author":"Chousou","year":"2024","journal-title":"Eur Hear J Open"},{"key":"2025032522412114100_zwaf138-B28","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1161\/STROKEAHA.116.016414","article-title":"Embolic stroke of undetermined source: a systematic review and clinical update","volume":"48","author":"Hart","year":"2017","journal-title":"Stroke"},{"key":"2025032522412114100_zwaf138-B29","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.amjcard.2019.10.050","article-title":"Detecting atrial fibrillation in patients with an embolic stroke of undetermined source (from the DAF-ESUS registry)","volume":"125","author":"Rubio Campal","year":"2020","journal-title":"Am J Cardiol"},{"key":"2025032522412114100_zwaf138-B30","doi-asserted-by":"crossref","first-page":"2467","DOI":"10.1056\/NEJMoa1311376","article-title":"Atrial fibrillation in patients with cryptogenic stroke","volume":"370","author":"Gladstone","year":"2014","journal-title":"N Engl J Med"},{"key":"2025032522412114100_zwaf138-B31","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1212\/WNL.0b013e31828f1828","article-title":"Incidence of atrial fibrillation detected by implantable loop recorders in unexplained stroke","volume":"80","author":"Cotter","year":"2013","journal-title":"Neurology"},{"key":"2025032522412114100_zwaf138-B32","doi-asserted-by":"crossref","first-page":"1265269","DOI":"10.3389\/fcvm.2023.1265269","article-title":"Effects of rhythm control on left atrial structure remodeling in atrial fibrillation and heart failure with preserved ejection fraction","volume":"10","author":"Bai","year":"2023","journal-title":"Front Cardiovasc Med"},{"key":"2025032522412114100_zwaf138-B33","doi-asserted-by":"crossref","first-page":"949213","DOI":"10.3389\/fcvm.2022.949213","article-title":"Multimodal approach for the prediction of atrial fibrillation detected after stroke: SAFAS study","volume":"9","author":"Garnier","year":"2022","journal-title":"Front Cardiovasc Med"},{"key":"2025032522412114100_zwaf138-B34","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1136\/svn-2023-002447","article-title":"Distribution of atrial cardiomyopathy markers and association with atrial fibrillation detected after ischaemic stroke in the SAFAS study","volume":"9","author":"Didier","year":"2024","journal-title":"Stroke Vasc Neurol"},{"key":"2025032522412114100_zwaf138-B35","first-page":"E016197","article-title":"Left atrial strain predicts subclinical atrial fibrillation detected by long-term continuous monitoring in elderly high-risk individuals","volume":"17","author":"Olsen","year":"2024","journal-title":"Circ Cardiovasc Imaging"},{"key":"2025032522412114100_zwaf138-B36","doi-asserted-by":"crossref","first-page":"euad272","DOI":"10.1093\/europace\/euad272","article-title":"Asymptomatic atrial fibrillation among hospitalized patients: clinical correlates and in-hospital outcomes in improving care for cardiovascular disease in China-atrial fibrillation","volume":"25","author":"Lin","year":"2023","journal-title":"Europace"},{"key":"2025032522412114100_zwaf138-B37","doi-asserted-by":"crossref","first-page":"2982","DOI":"10.1016\/j.jacc.2020.11.010","article-title":"Global burden of cardiovascular diseases and risk factors, 1990\u20132019: update from the GBD 2019 study","volume":"76","author":"Roth","year":"2020","journal-title":"J Am Coll Cardiol"},{"key":"2025032522412114100_zwaf138-B38","doi-asserted-by":"crossref","first-page":"e0265498","DOI":"10.1371\/journal.pone.0265498","article-title":"Epidemiology of atrial fibrillation in the all of us research program","volume":"17","author":"Alonso","year":"2022","journal-title":"PLoS One"},{"key":"2025032522412114100_zwaf138-B39","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1177\/1747493019897870","article-title":"Global epidemiology of atrial fibrillation: an increasing epidemic and public health challenge","volume":"16","author":"Lippi","year":"2020","journal-title":"Int J Stroke"},{"key":"2025032522412114100_zwaf138-B40","doi-asserted-by":"crossref","first-page":"19","DOI":"10.2174\/1573403X18666220901102557","article-title":"CHARGE-AF: a useful score for atrial fibrillation prediction?","volume":"19","author":"Goudis","year":"2023","journal-title":"Curr Cardiol Rev"},{"key":"2025032522412114100_zwaf138-B41","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.chest.2018.09.011","article-title":"A simple clinical risk score (C2HEST) for predicting incident atrial fibrillation in Asian subjects: derivation in 471,446 Chinese subjects, with internal validation and external application in 451,199 Korean subjects","volume":"155","author":"Li","year":"2019","journal-title":"Chest"},{"key":"2025032522412114100_zwaf138-B42","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.3390\/jcm10112321","article-title":"Predicting silent atrial fibrillation in the elderly: a report from the nomed-af cross-sectional study","volume":"10","author":"Mitrega","year":"2021","journal-title":"J Clin Med"},{"key":"2025032522412114100_zwaf138-B43","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1093\/europace\/euaa005","article-title":"Prediction models for atrial fibrillation applicable in the community: a systematic review and meta-analysis","volume":"22","author":"Himmelreich","year":"2020","journal-title":"Europace"},{"key":"2025032522412114100_zwaf138-B44","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1093\/eurjpc\/zwae045","article-title":"Burden of cardiometabolic disorders and lifetime risk of new-onset atrial fibrillation among men and women: the Rotterdam study","volume":"31","author":"Lu","year":"2024","journal-title":"Eur J Prev Cardiol"},{"key":"2025032522412114100_zwaf138-B45","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1093\/eurjpc\/zwae303","article-title":"Phenotypic characterization of people at risk of atrial fibrillation: protocol for the FIND-AF longitudinal cohort study","volume":"31","author":"Wahab","year":"2024","journal-title":"Eur J Prev Cardiol"},{"key":"2025032522412114100_zwaf138-B46","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1093\/eurjpc\/zwac083","article-title":"Sex-specific anthropometric and blood pressure trajectories and risk of incident atrial fibrillation: the Rotterdam study","volume":"29","author":"Lu","year":"2022","journal-title":"Eur J Prev Cardiol"},{"key":"2025032522412114100_zwaf138-B47","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1160\/TH16-11-0825","article-title":"Are cardiovascular risk factors also associated with the incidence of atrial fibrillation?: a systematic review and field synopsis of 23 factors in 32 population-based cohorts of 20 million participants","volume":"117","author":"Allan","year":"2017","journal-title":"Thromb Haemost"},{"key":"2025032522412114100_zwaf138-B48","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s12913-024-11100-1","article-title":"Epidemiology and comprehensive economic impact of atrial fibrillation and associated stroke in Slovakia","volume":"24","author":"Babela","year":"2024","journal-title":"BMC Health Serv Res"},{"key":"2025032522412114100_zwaf138-B49","doi-asserted-by":"crossref","first-page":"2104","DOI":"10.1093\/eurjpc\/zwae312","article-title":"A randomized controlled implementation study integrating patient self-screening with a remote central monitoring system to screen community dwellers aged 75 years and older for atrial fibrillation","volume":"31","author":"Wong","year":"2024","journal-title":"Eur J Prev Cardiol"},{"key":"2025032522412114100_zwaf138-B50","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2024.08.051","article-title":"Atrial fibrillation burden: stepping beyond the categorical characterization","author":"Doundoulakis","year":"2024","journal-title":"Hear Rhythm"},{"key":"2025032522412114100_zwaf138-B51","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1093\/europace\/euac144","article-title":"Searching for atrial fibrillation: looking harder, looking longer, and in increasingly sophisticated ways. An EHRA position paper","volume":"25","author":"Kalarus","year":"2023","journal-title":"Europace"},{"key":"2025032522412114100_zwaf138-B52","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1016\/S0140-6736(21)01637-8","article-title":"Clinical outcomes in systematic screening for atrial fibrillation (STROKESTOP): a multicentre, parallel group, unmasked, randomised controlled trial","volume":"398","author":"Svennberg","year":"2021","journal-title":"Lancet"},{"key":"2025032522412114100_zwaf138-B53","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1016\/S0140-6736(21)01698-6","article-title":"Implantable loop recorder detection of atrial fibrillation to prevent stroke (the LOOP study): a randomised controlled trial","volume":"398","author":"Svendsen","year":"2021","journal-title":"Lancet"},{"key":"2025032522412114100_zwaf138-B54","doi-asserted-by":"publisher","DOI":"10.1093\/ehjqcco\/qcae114","article-title":"Atrial fibrillation screening and clinical outcomes: a meta-analysis of randomized controlled trials","author":"Nyaga","year":"2025","journal-title":"Eur Hear J\u2014Qual Care Clin Outcomes"},{"key":"2025032522412114100_zwaf138-B55","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1093\/eurheartj\/ehae225","article-title":"Oral anticoagulation in device-detected atrial fibrillation: effects of age, sex, cardiovascular comorbidities, and kidney function on outcomes in the NOAH-AFNET 6 trial","volume":"45","author":"Lip","year":"2024","journal-title":"Eur Heart J"},{"key":"2025032522412114100_zwaf138-B56","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1056\/NEJMoa2019422","article-title":"Early rhythm-control therapy in patients with atrial fibrillation","volume":"383","author":"Kirchhof","year":"2020","journal-title":"N Engl J Med"},{"key":"2025032522412114100_zwaf138-B57","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2024.12.026","article-title":"Catheter ablation of paroxysmal atrial fibrillation and disease progression: magnitude of the antiprogression effect and role of intervention timing","author":"Benali","year":"2025","journal-title":"Hear Rhythm"},{"key":"2025032522412114100_zwaf138-B58","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1002\/joa3.13056","article-title":"Revitalizing brain perfusion: unveiling advancements through rhythm control strategies in atrial fibrillation-A systematic review","volume":"40","author":"Rasti","year":"2024","journal-title":"J Arrhythmia"},{"key":"2025032522412114100_zwaf138-B59","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.ijcard.2016.12.025","article-title":"Asymptomatic versus symptomatic episodes in patients with paroxysmal atrial fibrillation via long-term monitoring with implantable loop recorders","volume":"231","author":"Simantirakis","year":"2017","journal-title":"Int J Cardiol"},{"key":"2025032522412114100_zwaf138-B60","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1001\/jamainternmed.2013.1561","article-title":"Discerning the incidence of symptomatic and asymptomatic episodes of atrial fibrillation before and after catheter ablation (DISCERN AF): a prospective, multicenter study","volume":"173","author":"Verma","year":"2013","journal-title":"JAMA Intern Med"}],"container-title":["European Journal of Preventive Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/eurjpc\/advance-article-pdf\/doi\/10.1093\/eurjpc\/zwaf138\/62340649\/zwaf138.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurjpc\/advance-article-pdf\/doi\/10.1093\/eurjpc\/zwaf138\/62340649\/zwaf138.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,29]],"date-time":"2025-03-29T03:49:52Z","timestamp":1743220192000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurjpc\/advance-article\/doi\/10.1093\/eurjpc\/zwaf138\/8063648"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,7]]},"references-count":60,"URL":"https:\/\/doi.org\/10.1093\/eurjpc\/zwaf138","relation":{},"ISSN":["2047-4873","2047-4881"],"issn-type":[{"value":"2047-4873","type":"print"},{"value":"2047-4881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,7]]},"article-number":"zwaf138"}}