{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T13:25:05Z","timestamp":1783776305744,"version":"3.55.0"},"reference-count":71,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T00:00:00Z","timestamp":1750809600000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>This narrative review underscores the pivotal role of vaccination in mitigating respiratory infections and associated acute decompensations in heart failure (HF) patients. It highlights the necessity for heightened awareness and proactive engagement among healthcare providers to bridge vaccination gaps and enhance preventive care for HF patients. Respiratory pathogens, such as influenza, pneumococcus, SARS-CoV2, and Varicella zoster virus, instigate systemic inflammation and increase cardiovascular events, markedly elevating the risk of HF and strokes, especially in individuals with pre-existing conditions. Respiratory infections further amplify the risk of thrombotic events in HF patients through mechanisms involving a heightened pro-coagulant status due to inflammation. Systemic inflammation often accompanies HF, contributing to its progression, complications, and acute episodes, particularly during respiratory infections. While promising therapeutic approaches are under development, the review aims to provide a comprehensive overview of the pathophysiology linking inflammation, infection, and HF. The review then explores current clinical knowledge on the protective effects of vaccines against respiratory diseases (influenza, pneumococcal infection, SARS-CoV2, respiratory syncytial virus, and emerging pathogens) in HF patients, along with the key applicable guidelines. It also offers strategies to enhance vaccination coverage in HF patients, highlighting practical issues pertinent to daily clinical practice.<\/jats:p>","DOI":"10.1093\/eurjpc\/zwaf366","type":"journal-article","created":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T14:19:11Z","timestamp":1750861151000},"source":"Crossref","is-referenced-by-count":6,"title":["Vaccination in patients with heart failure in practice"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5288-9687","authenticated-orcid":false,"given":"Fran\u00e7ois","family":"Roubille","sequence":"first","affiliation":[{"name":"Cardiology Department, INI-CRT, CHU de Montpellier, PhyMedExp, Universit\u00e9 de Montpellier, INSERM, CNRS \u00a0 Montpellier 34295, 371 Avenue doyen GIRAUD, 34295 MONTPELLIER Cesex; \u00a0","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Chapet","sequence":"additional","affiliation":[{"name":"Cardiology Department, INI-CRT, CHU de Montpellier, PhyMedExp, Universit\u00e9 de Montpellier, INSERM, CNRS \u00a0 Montpellier 34295, 371 Avenue doyen GIRAUD, 34295 MONTPELLIER Cesex; \u00a0","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5268-1704","authenticated-orcid":false,"given":"Camille","family":"Roubille","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, CHU Montpellier, Montpellier University, PhyMedExp , Montpellier 34295 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-3958-7572","authenticated-orcid":false,"given":"Marc","family":"Villac\u00e8que","sequence":"additional","affiliation":[{"name":"Cardio N\u00eemes Sud , N\u00eemes ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e9ment","family":"Delmas","sequence":"additional","affiliation":[{"name":"Service de Cardiologie, CHU de Toulouse-Rangueil, Universit\u00e9 Paul Sabatier\u2013Toulouse III , Toulouse 31400 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muriel","family":"Salvat","sequence":"additional","affiliation":[{"name":"CHU Grenoble Alpes La Tronche 38700, University of Grenoble ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Mouquet","sequence":"additional","affiliation":[{"name":"Department of Cardiology, H\u00f4pital Priv\u00e9 Le Bois , Lille 59000 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thibaud","family":"Damy","sequence":"additional","affiliation":[{"name":"Referral Center for Cardiac Amyloidoisis, Department of Cardiology, GHU Henri Mondor-APHP, IMRB 955 , Cr\u00e9teil 94000 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Michel","family":"Tartiere","sequence":"additional","affiliation":[{"name":"CHITS, Department of Cardiology, H\u00f4pital Sainte-Musse , Toulon 83100 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuelle","family":"Berthelot","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, INSERM, UMR_S 999, Hypertension Pulmonaire: Physiopathologie and Innovation Th\u00e9rapeutique (HPPIT), AP-HP, H\u00f4pital Bic\u00eatre, H\u00f4pital Marie Lannelongue (Groupe Hospitalier Paris Saint Joseph), ERN-LUNG , Le Kremlin-Bic\u00eatre ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1502-502X","authenticated-orcid":false,"given":"Peter","family":"Libby","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School , Boston, MA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluigi","family":"Savarese","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Education, S\u00f6dersjukhuset; Karolinska Institutet , Stockholm ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1218-9432","authenticated-orcid":false,"given":"Paul","family":"Loubet","sequence":"additional","affiliation":[{"name":"Virulence Bact\u00e9rienne et Infections Chroniques, INSERM U1047, Univ Montpellier, Service des Maladies Infectieuses et Tropicales, CHU N\u00eemes , N\u00eemes ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Girerd","sequence":"additional","affiliation":[{"name":"Centre D\u2019Investigations Cliniques\u2014INSERM CHRU de Nancy, Institut Lorrain du C\u0153ur et des Vaisseaux Louis Mathieu, Universit\u00e9 de Lorraine \u00a0 Vand\u0153uvre-l\u00e8s-Nancy 54500 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,6,25]]},"reference":[{"key":"2025071008211937500_zwaf366-B1","doi-asserted-by":"crossref","first-page":"4911","DOI":"10.1016\/j.vaccine.2022.06.071","article-title":"Pneumococcal and influenza vaccination coverage among at-risk adults: a 5-year French national observational study","volume":"40","author":"Wyplosz","year":"2022","journal-title":"Vaccine"},{"key":"2025071008211937500_zwaf366-B2","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1016\/j.jacc.2021.03.001","article-title":"Incidence and outcomes of pneumonia in patients with heart failure","volume":"77","author":"Shen","year":"2021","journal-title":"J Am Coll 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