{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T02:51:29Z","timestamp":1788576689948,"version":"build-2803163510"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Adelphi Research"},{"DOI":"10.13039\/501100021515","name":"Sanofi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100021515","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Lowering LDL cholesterol (LDL-C) levels reduce cardiovascular risk in patients after acute coronary syndrome (ACS). This study evaluated cardiologists\u2019 lipid management practice in the acute and follow-up phases, comparing the year 2024 with 2022 and 2018, the year before the publication of the 2019 European Atherosclerosis Society\/European Society of Cardiology lipid guidelines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>The surveys in 2024, 2022, and 2018 were conducted using the same methodology. Five hundred thirty cardiologists from 6 European countries provided data on 2650 patients with ACS (33% acute phase, 67% follow-up). Additionally, a subgroup of cardiologists received training on guideline implementation, and their performance was compared with the main group. Lipid testing in the acute phase was performed in 86% of patients in 2024 vs. 90% in 2022 and 90% in 2018. LDL-C was tested in 97% of acute phase patients, similar to 2022 and 2018. Non-HDL-C and lipoprotein(a) testing increased over time. High-intensity statin monotherapy at discharge decreased (33% in 2024 vs. 44% in 2022 and 59% in 2018), while statin + ezetimibe prescription increased over time (37% in 2024 vs. 34% in 2022; 13% in 2018). The use of bempedoic acid and combinations with proprotein convertase subtilisin\/kexin type 9 inhibitors increased. Most patients were not treated to LDL-C goals, but LDL-C goal attainment improved (42% in 2024 vs. 31% in 2022 and 14% in 2018). Trained cardiologists showed improvements in lipid testing and therapies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The survey shows earlier lipid assessment, increased combination therapy use, and improved LDL-C goal achievement over time. Training enhanced guideline adherence, emphasizing the need for continuous efforts to achieve LDL-C goals.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/eurjpc\/zwaf399","type":"journal-article","created":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T07:29:34Z","timestamp":1751268574000},"page":"2006-2016","source":"Crossref","is-referenced-by-count":7,"title":["The ACS EuroPath survey series: time trends in lipid management after an acute coronary syndrome"],"prefix":"10.1093","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2620-9323","authenticated-orcid":false,"given":"Ulrich","family":"Laufs","sequence":"first","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Kardiologie, Universit\u00e4tsklinikum Leipzig , Liebigstra\u00dfe 20, 04103 Leipzig ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1637-574X","authenticated-orcid":false,"given":"Raffaele","family":"De Caterina","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Pisa , Via Paradisa, 2, 56124 Pisa ,","place":["Italy"]},{"name":"Cardiovascular Division, Pisa University Hospital , Via Piero Trivella, 30, 56124 Pisa ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4974-6551","authenticated-orcid":false,"given":"Fran\u00e7ois","family":"Schiele","sequence":"additional","affiliation":[{"name":"Department of Cardiology, SINERGIES, University Hospital Jean Minjoz, 3 Bd Alexandre Fleming, 25000 Besan\u00e7on ,","place":["France"]},{"name":"EA3920, University of Burgundy Franche-Comte , 32 Av. de l'Observatoire, 25000 Besan\u00e7on ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0843-9512","authenticated-orcid":false,"given":"Alessandro","family":"Sionis","sequence":"additional","affiliation":[{"name":"Cardiology Department, Hospital de la Santa Creu I Sant Pau, IIB-Sant Pau, Universitat Aut\u1f41noma de Barcelona , Carrer de Sant Quint\u00ed, 89, Horta-Guinard\u00f3, 08025 Barcelona ,","place":["Spain"]},{"name":"Centro de Investigaci\u1f40n Biom\u00e9dica en Red de Enfermedades Cardiovasculares (CIBERCV) Division of Cardiology, , v. Monforte de Lemos, 3-5, 28029 Madrid ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4891-8892","authenticated-orcid":false,"given":"Azfar","family":"Zaman","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Freeman Hospital and Newcastle University , Freeman Rd, High Heaton, Newcastle-upon-Tyne NE7 7DN ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7593-2094","authenticated-orcid":false,"given":"Alberico Luigi","family":"Catapano","sequence":"additional","affiliation":[{"name":"IRCCS MultiMedica Center for the Study of Atherosclerosis, , Via Milanese, 300, 20099 Sesto S. 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