{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:46:53Z","timestamp":1791852413730,"version":"4.3.4"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"14","license":[{"start":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T00:00:00Z","timestamp":1763942400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,13]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To assess the association between body mass index (BMI) and 10-year clinical outcomes in patients undergoing percutaneous coronary intervention (PCI) with drug-eluting stent (DES) implantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is a pooled analysis of five randomized trials with 10-year follow-up. All-cause death was the primary outcome. Secondary outcomes were cardiovascular death, myocardial infarction (MI), definite stent thrombosis (ST), and repeat revascularization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 9486 patients were analysed divided into four BMI groups (underweight [n = 92], normal-weight [n = 2785], overweight [n = 4296], and obese [n = 2313]). After 10 years, the risk of all-cause death was significantly higher in underweight patients than in those of normal weight (adjusted hazard ratio [HRadj], 1.58; 95% confidence interval [CI], 1.01\u20132.47). Compared with normal-weight patients, overweight patients had a significantly lower risk of all-cause death (HRadj, 0.84; 95% CI, 0.78\u20130.90) and cardiovascular death, while the difference was not significant for obese patients. Overweight and obese patients had a significantly higher risk of definite ST within 30 days, while obese patients had a significantly lower risk of TLR than normal-weight patients. There was a U-shaped, non-linear association between BMI, all-cause death, and cardiovascular death.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The baseline BMI of patients undergoing PCI with DES may have important implications for long-term secondary prevention strategies. Further dedicated studies are needed to overcome the limitations of the current analysis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/eurjpc\/zwaf753","type":"journal-article","created":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T12:58:39Z","timestamp":1763816319000},"page":"2613-2623","source":"Crossref","is-referenced-by-count":2,"title":["Association of body mass index on 10-year outcomes in patients treated with percutaneous coronary intervention and drug-eluting stents (the DECADE cooperation)"],"prefix":"10.1093","volume":"33","author":[{"given":"Maria","family":"Scalamogna","sequence":"first","affiliation":[{"name":"Klinik f\u00fcr Herz- und Kreislauferkrankungen, TUM Klinikum Deutsches Herzzentrum , Technische Universit\u00e4t M\u00fcnchen, Lazarettstra\u00dfe 36, Munich 80636 ,","place":["Germany"]},{"name":"Department of Advanced Biomedical Sciences, University of Naples Federico II , Naples 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