{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T22:38:03Z","timestamp":1791412683568,"version":"4.3.3"},"reference-count":45,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T00:00:00Z","timestamp":1767657600000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012266","name":"NRF","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012266","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Korea government"},{"DOI":"10.13039\/501100014188","name":"MSIT","doi-asserted-by":"publisher","award":["RS-2024-00449868"],"award-info":[{"award-number":["RS-2024-00449868"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"MSIT","doi-asserted-by":"publisher","award":["RS-2024-00438808"],"award-info":[{"award-number":["RS-2024-00438808"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Myocardial infarction (MI) and stroke significantly affect health, quality of life, and socioeconomic stability. We investigated the association of MI and stroke with the risk of suicide.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>This nationwide population-based cohort study used Korean National Health Insurance Service data on all patients diagnosed with atherosclerotic cardiovascular disease (ASCVD), defined as a composite of MI or stroke, between 1 January 2004, and 31 December 2008. For each patient, five age- and sex-matched controls were selected. All participants were followed up from diagnosis (or the corresponding entry date for controls) until suicide, other causes of death, or 31 December 2021, whichever occurred first. This study included 37 912 individuals with ASCVD and 189 560 matched controls. During a median follow-up of 11.3 years, 1250 suicides occurred. The incidence rate of suicide per 1000 person-years were 0.737 and 0.497 among individuals with and without ASCVD, respectively. Multivariable analysis showed a significantly higher risk of suicide for individuals with ASCVD [hazard ratio (HR), 1.43; 95% confidence interval (CI), 1.24\u20131.65], with HRs of 1.42 (95% CI, 1.14\u20131.78) for MI and 1.47 (95% CI, 1.23\u20131.76) for stroke. The risk of suicide increased further in individuals with both MI and stroke (HR, 1.85; 95% CI, 1.07\u20133.21). The association between ASCVD and increased suicide risk was consistent across age, sex, and a history of depressive disorder.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Individuals with ASCVD have increased risks of suicide. Our findings suggest the importance of screening and preventing suicidal ideation in individuals with ASCVD to improve prognosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/eurjpc\/zwag013","type":"journal-article","created":{"date-parts":[[2026,1,3]],"date-time":"2026-01-03T12:25:13Z","timestamp":1767443113000},"source":"Crossref","is-referenced-by-count":2,"title":["Risk of suicide in individuals with atherosclerotic cardiovascular disease: a nationwide population-based study"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7443-1132","authenticated-orcid":false,"given":"Nan Young","family":"Bae","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Seoul National University Hospital , 101 Daehak-ro, Jongno-gu, Seoul 03080 ,","place":["Republic of Korea"]},{"name":"Department of Internal Medicine, Seoul National University College of Medicine , Seoul ,","place":["Republic of 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06978 ,","place":["Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4037-3955","authenticated-orcid":false,"given":"Heesun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Seoul National University College of Medicine , Seoul ,","place":["Republic of Korea"]},{"name":"Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital Healthcare System Gangnam Center , 369 Sangdo-ro, Dongjak-gu, Seoul 06978 ,","place":["Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7950-2131","authenticated-orcid":false,"given":"Hyung-Kwan","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Seoul National University Hospital , 101 Daehak-ro, Jongno-gu, Seoul 03080 ,","place":["Republic of Korea"]},{"name":"Department of Internal Medicine, Seoul National University College of Medicine , Seoul ,","place":["Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1366-432X","authenticated-orcid":false,"given":"Yong-Jin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Seoul National University Hospital , 101 Daehak-ro, Jongno-gu, Seoul 03080 ,","place":["Republic of Korea"]},{"name":"Department of Internal Medicine, Seoul National University College of Medicine , Seoul ,","place":["Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8920-8777","authenticated-orcid":false,"given":"Jin-Hyung","family":"Jung","sequence":"additional","affiliation":[{"name":"Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine , Suwon ,","place":["Republic of 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