{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T15:43:53Z","timestamp":1792424633767,"version":"4.5.0"},"reference-count":41,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T00:00:00Z","timestamp":1792368000000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To evaluate whether mobility-derived greenspace visitation, as a behavioural measure of environmental exposure, is associated with major adverse cardiovascular events (MACE) independent of individual and neighbourhood factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>We conducted a retrospective cohort study of adults in the Houston Methodist Cardiovascular Disease Learning Health System Registry (2016\u20132023). Greenspace visitation was defined at the census-tract level using mobility-derived foot-traffic data and modelled as annual visits per resident device. The primary outcome was incident MACE (myocardial infarction, stroke, coronary revascularization, and all-cause mortality). The Cox models, restricted cubic splines, and Kaplan\u2013Meier curves assessed associations with sequential adjustment for demographics, comorbidities, smoking, and neighbourhood social vulnerability. Among 1 088 866 adults without baseline atherosclerotic cardiovascular disease, median (SD) age was 49 (17.6) years, and 59.9% were female. Greenspace visitation varied across neighbourhoods and by demographic and socioeconomic characteristics. Each additional 10 annual visits was associated with lower MACE risk in unadjusted models [hazard ratio (HR) 0.82; 95% confidence interval (CI): 0.81\u20130.83] and after adjustment for demographics, comorbidities, and smoking (HR 0.89; 95% CI: 0.88\u20130.91). A non-linear relationship showed risk reductions at low-to-moderate visitation, plateauing at 10\u201315 visits annually. After adjusting for social vulnerability, associations were attenuated and no longer significant. The Kaplan\u2013Meier curves showed higher event-free survival in high-visitation areas, consistent across MACE components.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Mobility-derived greenspace visitation is associated with lower cardiovascular risk. These findings highlight greenspace engagement as a potentially modifiable behavioural exposure and support strategies to enhance access and utilization of greenspaces for cardiovascular prevention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/eurjpc\/zwag470","type":"journal-article","created":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T15:34:43Z","timestamp":1792424083000},"source":"Crossref","is-referenced-by-count":0,"title":["Greenspace visitation and risk of major adverse cardiovascular events: evidence from the Houston methodist cardiovascular learning health system registry"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3981-658X","authenticated-orcid":false,"given":"Weichuan","family":"Dong","sequence":"first","affiliation":[{"name":"Center for Health & Nature , Houston, TX 77030, USA"},{"name":"Center for Cardiovascular Computational and Precision Health (C3PH), Department of Cardiology, Houston Methodist DeBakey Heart & 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