{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T17:42:58Z","timestamp":1793036578307,"version":"4.5.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"DOI":"10.1093\/eurjpc\/zwag513","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T11:58:57Z","timestamp":1790769537000},"source":"Crossref","is-referenced-by-count":0,"title":["Fewer ischaemic events, more bleeding after myocardial infarction: interpreting two decades of change"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6292-4207","authenticated-orcid":false,"given":"Jacqueline","family":"Bosch","sequence":"first","affiliation":[{"name":"Population Health Research Institute, Hamilton Health Sciences and McMaster University , 237 Barton Street East, Hamilton, Ontario L8L 2X2 ,","place":["Canada"]},{"name":"School of Rehabilitation Science, McMaster University , IAHS 1400 Main Street West, Hamilton, ON L8S 1C7, Ontario ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3806-3245","authenticated-orcid":false,"given":"Deborah M","family":"Siegal","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Ottawa , Ottawa, Ontario ,","place":["Canada"]},{"name":"Inflammation and Chronic Disease Program, Ottawa Hospital Research Institute , Ottawa, Ontario ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John W","family":"Eikelboom","sequence":"additional","affiliation":[{"name":"Population Health Research Institute, Hamilton Health Sciences and McMaster University , 237 Barton Street East, Hamilton, Ontario L8L 2X2 ,","place":["Canada"]},{"name":"Department of Medicine, McMaster University , Hamilton, Ontario ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,10,1]]},"reference":[{"key":"2026102613250122100_zwag513-B1","doi-asserted-by":"publisher","DOI":"10.1093\/eurjpc\/zwag508","article-title":"Long-term trends in upper gastrointestinal bleeding and ischemic outcomes after myocardial infarction","author":"W\u00e4rme","journal-title":"Eur J Prev Cardiol"},{"key":"2026102613250122100_zwag513-B2","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1007\/s11886-023-01892-9","article-title":"Personalized dual antiplatelet therapy in acute coronary syndromes: striking a balance between bleeding and thrombosis","volume":"25","author":"Shpigelman","year":"2023","journal-title":"Curr Cardiol Rep"},{"key":"2026102613250122100_zwag513-B3","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1001\/jama.2025.15047","article-title":"Helicobacter pylori screening after acute myocardial infarction: the cluster randomized crossover HELP-MI SWEDEHEART trial","volume":"334","author":"Hofmann","year":"2025","journal-title":"JAMA"},{"key":"2026102613250122100_zwag513-B4","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1161\/CIRCULATIONAHA.106.612812","article-title":"Adverse impact of bleeding on prognosis in patients with acute coronary syndromes","volume":"114","author":"Eikelboom","year":"2006","journal-title":"Circulation"},{"key":"2026102613250122100_zwag513-B5","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1053\/j.gastro.2026.02.028","article-title":"Cardiovascular outcomes following major gastrointestinal bleeding in patients with pre-existing cardiovascular disease: the INTERBLEED international prospective cohort study","volume":"171","author":"Forbes","year":"2026","journal-title":"Gastroenterology"},{"key":"2026102613250122100_zwag513-B6","doi-asserted-by":"publisher","DOI":"10.1093\/eurjpc\/zwaf300","article-title":"Risk factors associated with gastrointestinal bleeding in patients with cardiovascular disease (INTERBLEED): a case control study","author":"Bosch","journal-title":"Eur J Prev Cardiol"},{"key":"2026102613250122100_zwag513-B7","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1056\/NEJMoa1007964","article-title":"Clopidogrel with or without omeprazole in coronary artery disease","volume":"363","author":"Bhatt","year":"2010","journal-title":"N Engl J Med"},{"key":"2026102613250122100_zwag513-B8","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1053\/j.gastro.2019.04.041","article-title":"Pantoprazole to prevent gastroduodenal events in patients receiving rivaroxaban and\/or aspirin in a randomized, double-blind, placebo-controlled trial","volume":"157","author":"Moayyedi","year":"2019","journal-title":"Gastroenterology"},{"key":"2026102613250122100_zwag513-B9","doi-asserted-by":"crossref","first-page":"2915","DOI":"10.1016\/j.jacc.2018.09.057","article-title":"ACC\/AHA versus ESC guidelines on dual antiplatelet therapy: JACC guideline comparison","volume":"72","author":"Capodanno","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"2026102613250122100_zwag513-B10","doi-asserted-by":"crossref","first-page":"3720","DOI":"10.1093\/eurheartj\/ehad191","article-title":"2023 ESC guidelines for the management of acute coronary syndromes","volume":"44","author":"Byrne","year":"2023","journal-title":"Eur Heart J"}],"container-title":["European Journal of Preventive Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/eurjpc\/advance-article-pdf\/doi\/10.1093\/eurjpc\/zwag513\/71540174\/zwag513.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurjpc\/advance-article-pdf\/doi\/10.1093\/eurjpc\/zwag513\/71540174\/zwag513.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T17:25:10Z","timestamp":1793035510000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurjpc\/advance-article\/doi\/10.1093\/eurjpc\/zwag513\/8857129"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,1]]},"references-count":10,"URL":"https:\/\/doi.org\/10.1093\/eurjpc\/zwag513","relation":{},"ISSN":["2047-4873","2047-4881"],"issn-type":[{"value":"2047-4873","type":"print"},{"value":"2047-4881","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,1]]},"article-number":"zwag513"}}