{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T23:18:47Z","timestamp":1784762327819,"version":"3.55.0"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2020,7,20]],"date-time":"2020-07-20T00:00:00Z","timestamp":1595203200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Boston Scientific, Cook Medical, Medtronic, Spectranetics, and Zoll"},{"name":"EPSRC Centre for Medical Engineering","award":["WT203148\/Z\/16\/Z"],"award-info":[{"award-number":["WT203148\/Z\/16\/Z"]}]},{"DOI":"10.13039\/501100000272","name":"National Institute for Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006662","name":"NIHR","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006662","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014461","name":"Biomedical Research Centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014461","id-type":"DOI","asserted-by":"publisher"}]},{"name":"NHS Foundation Trust and King\u2019s College London"},{"DOI":"10.13039\/501100003921","name":"Department of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003921","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims\u2003<\/jats:title>\n                  <jats:p>Transvenous lead extraction (TLE) should ideally be undertaken by experienced operators in a setting that allows urgent surgical intervention. In this analysis of the ELECTRa registry, we sought to determine whether there was a significant difference in procedure complications and mortality depending on centre volume and extraction location.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results\u2003<\/jats:title>\n                  <jats:p>Analysis of the ESC EORP European Lead Extraction ConTRolled ELECTRa registry was conducted. Low-volume (LoV) centres were defined as &amp;lt;30 procedures\/year, and high-volume (HiV) centres as \u226530 procedures\/year. Three thousand, two hundred, and forty-nine patients underwent TLE by a primary operator cardiologist; 17.1% in LoV centres and 82.9% in HiV centres. Procedures performed by primary operator cardiologists in LoV centres were less likely to be successful (93.5% vs. 97.1%; P\u2009&amp;lt;\u20090.0001) and more likely to be complicated by procedure-related deaths (1.1% vs. 0.4%; P\u2009=\u20090.0417). Transvenous lead extraction undertaken by primary operator cardiologists in LoV centres were associated with increased procedure-related major complications including death (odds ratio 1.858, 95% confidence interval 1.007\u20133.427; P\u2009=\u20090.0475). Transvenous lead extraction locations varied; 52.0% operating room, 9.5% hybrid theatre and 38.5% catheterization laboratory. Rates of procedure-related major complications, including death occurring in a high-risk environment (combining operating room and hybrid theatre), were similar to those undertaken in the catheterization laboratory (1.7% vs. 1.6%; P\u2009=\u20090.9297).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion\u2003<\/jats:title>\n                  <jats:p>Primary operator cardiologists in LoV centres are more likely to have extractions complicated by procedure-related deaths. There was no significant difference in procedure complications between different extraction settings. These findings support the need for TLE to be performed in experienced centres with appropriate personnel present.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/europace\/euaa131","type":"journal-article","created":{"date-parts":[[2020,4,30]],"date-time":"2020-04-30T19:12:03Z","timestamp":1588273923000},"page":"1718-1728","source":"Crossref","is-referenced-by-count":33,"title":["The effect of centre volume and procedure location on major complications and mortality from transvenous lead extraction: an ESC EHRA EORP European Lead Extraction ConTRolled ELECTRa registry subanalysis"],"prefix":"10.1093","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1999-7360","authenticated-orcid":false,"given":"Baldeep S","family":"Sidhu","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering and Imaging Sciences, King\u2019s College London, London, UK"},{"name":"Department of Cardiology, Guy\u2019s and St Thomas\u2019 Hospital, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Gould","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering and Imaging Sciences, King\u2019s College London, London, UK"},{"name":"Department of Cardiology, Guy\u2019s and St Thomas\u2019 Hospital, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catey","family":"Bunce","sequence":"additional","affiliation":[{"name":"Department of Population Health and Environmental Sciences, King's College London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Elliott","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering and Imaging Sciences, King\u2019s College London, London, UK"},{"name":"Department of Cardiology, Guy\u2019s and St Thomas\u2019 Hospital, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishal","family":"Mehta","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering and Imaging Sciences, King\u2019s College London, London, UK"},{"name":"Department of Cardiology, Guy\u2019s and St Thomas\u2019 Hospital, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Kennergren","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Sahlgrenska\/SU, 41345 Goteborg, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Butter","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Heart Center Brandenburg in Bernau\/Berlin & Brandenburg Medical School, Ladeburger Stra\u00dfe 17, 16321 Bernau, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Claude","family":"Deharo","sequence":"additional","affiliation":[{"name":"Department of Cardiology, CHU La Timone, Cardiologie, Service du prof Deharo, 264 Rue Saint Pierre, 13385 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrzej","family":"Kutarski","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Medical University of Lublin, Jaczewskiego Street Nr 8, 20-090 Lublin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aldo P","family":"Maggioni","sequence":"additional","affiliation":[{"name":"European Society of Cardiology, 2035 route des Colles, Biot, Sophia Antipolis, France"},{"name":"ANMCO Research Center, Via Alfonso la Marmora, 36, 50121 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Auricchio","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Fondazione Cardiocentro Ticino, Via Tesserete 48, 6900 Lugano, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl-Heinz","family":"Kuck","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Asklepios Klinik St. Georg, Lohm\u00fchlenstra\u00dfe 5, D-20099 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carina","family":"Blomstr\u00f6m-Lundqvist","sequence":"additional","affiliation":[{"name":"Department of Medical Science and Cardiology, Uppsala University, Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Grazia","family":"Bongiorni","sequence":"additional","affiliation":[{"name":"Cardiology Department, Direttore UO Cardiologia 2 SSN, Azienda Ospedaliero-Universitaria, Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher A","family":"Rinaldi","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering and Imaging Sciences, King\u2019s College London, London, UK"},{"name":"Department of Cardiology, Guy\u2019s and St Thomas\u2019 Hospital, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the ELECTRa Investigators Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,7,20]]},"reference":[{"key":"2020111111423868400_euaa131-B1","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1093\/europace\/euy050","article-title":"2018 EHRA expert consensus statement on lead extraction: recommendations on definitions, endpoints, research trial design, and data collection requirements for clinical scientific studies and registries: endorsed by APHRS\/HRS\/LAHRS","volume":"20","author":"Bongiorni","year":"2018","journal-title":"Europace"},{"key":"2020111111423868400_euaa131-B2","first-page":"1733","article-title":"The role of transvenous lead extraction in the management of redundant or malfunctioning pacemaker and defibrillator leads post ELECTRa","volume-title":"Europace","author":"Sidhu","year":"2018"},{"key":"2020111111423868400_euaa131-B3","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1093\/europace\/euy290","article-title":"Transvenous lead extraction in patients with cardiac resynchronization therapy devices is not associated with increased 30-day mortality","volume":"21","author":"Gould","year":"2019","journal-title":"Europace"},{"key":"2020111111423868400_euaa131-B4","doi-asserted-by":"crossref","first-page":"e503","DOI":"10.1016\/j.hrthm.2017.09.001","article-title":"2017 HRS expert consensus statement on cardiovascular implantable electronic device lead management and extraction","volume":"14","author":"Kusumoto","year":"2017","journal-title":"Heart Rhythm"},{"key":"2020111111423868400_euaa131-B5","doi-asserted-by":"crossref","first-page":"2995","DOI":"10.1093\/eurheartj\/ehx080","article-title":"The European Lead 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U.S. Extraction Database, MED Institute","volume":"22","author":"Byrd","year":"1999","journal-title":"Pacing Clin Electro"},{"key":"2020111111423868400_euaa131-B10","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1111\/pace.13791","article-title":"Prolonged lead dwell time and lead burden predict bailout transfemoral lead extraction","volume":"42","author":"Gould","year":"2019","journal-title":"Pacing Clin Electrophysiol"},{"key":"2020111111423868400_euaa131-B11","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1111\/pace.12736","article-title":"Outcomes and complications of lead removal: can we establish a risk stratification schema for a collaborative and effective approach?","volume":"38","author":"Fu","year":"2015","journal-title":"Pacing Clin Electrophysiol"},{"key":"2020111111423868400_euaa131-B12","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1093\/europace\/eur338","article-title":"Pathways for training and accreditation for transvenous lead extraction: a European Heart Rhythm Association position paper","volume":"14","author":"Deharo","year":"2012","journal-title":"Europace"},{"key":"2020111111423868400_euaa131-B13","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.jacep.2019.01.001","article-title":"Efficacy and safety of transvenous lead extraction in the device laboratory and operating room guided by a novel risk stratification scheme","volume":"5","author":"Kancharla","year":"2019","journal-title":"JACC Clin Electrophysiol"},{"key":"2020111111423868400_euaa131-B14","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1111\/jce.13223","article-title":"Predicting the difficulty of a transvenous lead extraction procedure: validation of the LED index","volume":"28","author":"Bontempi","year":"2017","journal-title":"J Cardiovasc Electrophysiol"}],"container-title":["EP Europace"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/europace\/article-pdf\/22\/11\/1718\/34247394\/euaa131.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/europace\/article-pdf\/22\/11\/1718\/34247394\/euaa131.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T16:43:11Z","timestamp":1605112991000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/europace\/article\/22\/11\/1718\/5874070"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,20]]},"references-count":14,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2020,7,20]]},"published-print":{"date-parts":[[2020,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/europace\/euaa131","relation":{},"ISSN":["1099-5129","1532-2092"],"issn-type":[{"value":"1099-5129","type":"print"},{"value":"1532-2092","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,11]]},"published":{"date-parts":[[2020,7,20]]}}}