{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T17:59:48Z","timestamp":1760551188187},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2020,8,23]],"date-time":"2020-08-23T00:00:00Z","timestamp":1598140800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>No data exist concerning the clinical performances of the subcutaneous implantable cardioverter-defibrillator (S-ICD) atrial fibrillation (AF) detection algorithm. We aimed to study the performances and implications of the latter in a \u2018real-world\u2019 setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>Between July 2017 and August 2019, 155 consecutive S-ICD recipients were included. Endpoint of the study was the incidence of de novo or recurrent AF using a combined on-site and remote-monitoring follow-up approach. After a mean follow-up of 13\u2009\u00b1\u20098\u2009months, 2531 AF alerts were generated for 55 patients. A blinded analysis of the 1950 subcutaneous electrocardiograms available was performed. Among them 47% were true AF, 23% were premature atrial contractions or non-sustained AF, 29% were premature ventricular contractions or non-sustained ventricular tachycardia, and 1% were misdetection. Fourteen percent (21\/155) patients had at least one correct diagnosis of AF by the S-ICD algorithm. One patient presented symptomatic paroxysmal AF not diagnosed by the S-ICD algorithm (false negative patient). Patient-based sensitivity, specificity, positive, and negative predictive values were respectively 95%, 74%, 38%, and 99%. Among patients with at least one correct diagnosis of AF, 38% (8\/21) had subsequent clinical implications (anticoagulation initiation or rhythm control therapies).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The S-ICD AF detection algorithm yields a high sensitivity for AF diagnosis. Low specificity and positive predictive value contribute to a high remote monitoring-notification workload and underline the necessity of a manual analysis. Atrial fibrillation diagnosis by the S-ICD AF detection algorithm might lead to significant therapeutic adjustments.<\/jats:p><\/jats:sec>","DOI":"10.1093\/europace\/euaa184","type":"journal-article","created":{"date-parts":[[2020,8,4]],"date-time":"2020-08-04T19:28:17Z","timestamp":1596569297000},"page":"1628-1634","source":"Crossref","is-referenced-by-count":2,"title":["Atrial fibrillation detection by the subcutaneous defibrillator: real-world clinical performances and implications from a multicentre study"],"prefix":"10.1093","volume":"22","author":[{"given":"Pierre","family":"Ollitrault","sequence":"first","affiliation":[{"name":"Department of Cardiology, Caen University Hospital, Normandie Univ, UniCaen, Avenue de la C\u00f4te de Nacre, F-14000 Caen, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peggy","family":"Jacon","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Grenoble-Alpes University Hospital, Avenue Maquis du Gr\u00e9sivaudan, F-38043 Grenoble, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathana\u00ebl","family":"Auquier","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Le Havre Hospital Center, Avenue Mend\u00e8s France, F-76290 Montivilliers, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laure","family":"Champ-Rigot","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Caen University Hospital, Normandie Univ, UniCaen, Avenue de la C\u00f4te de Nacre, F-14000 Caen, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mouna","family":"Ben Kilani","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Grenoble-Alpes University Hospital, Avenue Maquis du Gr\u00e9sivaudan, F-38043 Grenoble, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florence","family":"Vandevelde","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Le Havre Hospital Center, Avenue Mend\u00e8s France, F-76290 Montivilliers, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnaud","family":"Pellissier","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Caen University Hospital, Normandie Univ, UniCaen, Avenue de la C\u00f4te de Nacre, F-14000 Caen, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virginie","family":"Ferchaud","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Caen University Hospital, Normandie Univ, UniCaen, Avenue de la C\u00f4te de Nacre, F-14000 Caen, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damien","family":"Legallois","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Caen University Hospital, Normandie Univ, UniCaen, Avenue de la C\u00f4te de Nacre, F-14000 Caen, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascal","family":"Defaye","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Grenoble-Alpes University Hospital, Avenue Maquis du Gr\u00e9sivaudan, F-38043 Grenoble, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Anselme","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rouen University Hospital, Normandie Univ, UniRouen, Rue de Germont, F-76031 Rouen, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Milliez","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Caen University Hospital, Normandie Univ, UniCaen, Avenue de la C\u00f4te de Nacre, F-14000 Caen, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,8,23]]},"reference":[{"key":"2020111111424554700_euaa184-B1","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1093\/europace\/eux177","article-title":"Screening for atrial fibrillation: an European Heart Rhythm association (EHRA) consensus document endorsed by Heart Rhythm Society (HRS), Asia Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofixiologia (SOLAECE)","volume":"19","author":"Mairesse","year":"2017","journal-title":"Europace"},{"key":"2020111111424554700_euaa184-B2","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1093\/eurheartj\/ehz834","article-title":"Screening for atrial fibrillation: a call for evidence","volume":"41","author":"Jones","year":"2020","journal-title":"Eur Heart 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