{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T11:08:36Z","timestamp":1784027316012,"version":"3.55.0"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2020,12,26]],"date-time":"2020-12-26T00:00:00Z","timestamp":1608940800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100000860","name":"European Society of Cardiology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000860","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Cardiopath PhD programme"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,6,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Catheter ablation of paroxysmal atrial fibrillation (AF) reduces AF recurrence, AF burden, and improves quality of life. Data on clinical and procedural predictors of arrhythmia recurrence are scarce and are flawed by the high rate of pulmonary vein reconnection evidenced during repeat procedures after pulmonary vein isolation (PVI). In this study, we identified clinical and procedural predictors for AF recurrence 1 year after CLOSE-guided PVI, as this strategy has been associated with an increased PVI durability.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>Patients with paroxysmal AF, who received CLOSE-guided PVI and who participated in a prospective trial in our centre, were included in this study. Uni- and multivariate models were plotted to find clinical and procedural predictors for AF recurrence within 1 year. Three hundred twenty-five patients with a mean age of 63\u2009years (CHA2DS2VASc 1 [1\u20133], left atrium diameter 41\u2009\u00b1\u20096 mm) were included. About 60.9% were male individuals. After 1 year, AF recurrence occurred in 10.5% of patients. In a binary logistic regression analysis, the diagnosis-to-ablation time (DAT) was found to be the strongest predictor of AF recurrence (P\u2009=\u20090.011). Diagnosis-to-ablation time \u22651\u2009year was associated with a nearly two-fold increased risk for developing AF recurrence.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>The DAT is the most important predictor of arrhythmia recurrence in low-risk patients treated with durable pulmonary vein isolation for paroxysmal AF. Whether reducing the DAT could improve long-term outcomes should be investigated in another trial.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/europace\/euaa383","type":"journal-article","created":{"date-parts":[[2020,12,2]],"date-time":"2020-12-02T14:38:35Z","timestamp":1606919915000},"page":"861-867","source":"Crossref","is-referenced-by-count":15,"title":["Predictors of recurrence after durable pulmonary vein isolation for paroxysmal atrial fibrillation"],"prefix":"10.1093","volume":"23","author":[{"given":"Michelle","family":"Lycke","sequence":"first","affiliation":[{"name":"Department of Cardiology, AZ Sint-Jan Brugge, Ruddershove 10, Bruges 8000, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Kyriakopoulou","sequence":"additional","affiliation":[{"name":"Department of Cardiology, AZ Sint-Jan Brugge, Ruddershove 10, Bruges 8000, Belgium"},{"name":"Faculty of Medicine, Universit\u00e9 Libre de Bruxelles (ULB), Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milad","family":"El Haddad","sequence":"additional","affiliation":[{"name":"Department of Cardiology, AZ Sint-Jan Brugge, Ruddershove 10, Bruges 8000, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Yves","family":"Wielandts","sequence":"additional","affiliation":[{"name":"Department of Cardiology, AZ Sint-Jan Brugge, Ruddershove 10, Bruges 8000, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"Hilfiker","sequence":"additional","affiliation":[{"name":"Department of Cardiology, AZ Sint-Jan Brugge, Ruddershove 10, Bruges 8000, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Almorad","sequence":"additional","affiliation":[{"name":"Department of Cardiology, AZ Sint-Jan Brugge, Ruddershove 10, Bruges 8000, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5928-1669","authenticated-orcid":false,"given":"Teresa","family":"Strisciuglio","sequence":"additional","affiliation":[{"name":"Department of Cardiology, AZ Sint-Jan Brugge, Ruddershove 10, Bruges 8000, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"De Pooter","sequence":"additional","affiliation":[{"name":"Department of Cardiology, AZ Sint-Jan Brugge, Ruddershove 10, Bruges 8000, Belgium"},{"name":"Department of Cardiology, UZ Gent, Ghent, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Wolf","sequence":"additional","affiliation":[{"name":"Department of Cardiology, AZ Sint-Jan Brugge, Ruddershove 10, Bruges 8000, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Unger","sequence":"additional","affiliation":[{"name":"Department of Cardiology, CHU Saint Pierre, Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Vandekerckhove","sequence":"additional","affiliation":[{"name":"Department of Cardiology, AZ Sint-Jan Brugge, Ruddershove 10, Bruges 8000, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e9","family":"Tavernier","sequence":"additional","affiliation":[{"name":"Department of Cardiology, AZ Sint-Jan Brugge, Ruddershove 10, Bruges 8000, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Beno\u00eet e Polain","family":"de Waroux","sequence":"additional","affiliation":[{"name":"Department of Cardiology, AZ Sint-Jan Brugge, Ruddershove 10, Bruges 8000, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mattias","family":"Duytschaever","sequence":"additional","affiliation":[{"name":"Department of Cardiology, AZ Sint-Jan Brugge, Ruddershove 10, Bruges 8000, 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