{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:58:09Z","timestamp":1787313489272,"version":"build-2736575974"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T00:00:00Z","timestamp":1617062400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Medical Research Grant, Ministry of Health, Malaysia","award":["NMRR-17-1342-36303"],"award-info":[{"award-number":["NMRR-17-1342-36303"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,7,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Atrial fibrillation (AF) is a preventable cause of ischaemic stroke but it is often undiagnosed and undertreated. The utility of smartphone electrocardiogram (ECG) for the detection of AF after ischaemic stroke is unknown. The aim of this study is to determine the diagnostic yield of 30-day smartphone ECG recording compared with 24-h Holter monitoring for detecting AF \u226530\u2009s.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>In this multicentre, open-label study, we randomly assigned 203 participants to undergo one additional 24-h Holter monitoring (control group, n\u2009=\u200998) vs. 30-day smartphone ECG monitoring (intervention group, n\u2009=\u2009105) using KardiaMobile (AliveCor\u00ae, Mountain View, CA, USA). Major inclusion criteria included age \u226555\u2009years old, without known AF, and ischaemic stroke or transient ischaemic attack (TIA) within the preceding 12\u2009months. Baseline characteristics were similar between the two groups. The index event was ischaemic stroke in 88.5% in the intervention group and 88.8% in the control group (P\u2009=\u20090.852). AF lasting \u226530\u2009s was detected in 10 of 105 patients in the intervention group and 2 of 98 patients in the control group (9.5% vs. 2.0%; absolute difference 7.5%; P\u2009=\u20090.024). The number needed to screen to detect one AF was 13. After the 30-day smartphone monitoring, there was a significantly higher proportion of patients on oral anticoagulation therapy at 3\u2009months compared with baseline in the intervention group (9.5% vs. 0%, P\u2009=\u20090.002).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Among patients \u226555\u2009years of age with a recent cryptogenic stroke or TIA, 30-day smartphone ECG recording significantly improved the detection of AF when compared with the standard repeat 24-h Holter monitoring.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/europace\/euab036","type":"journal-article","created":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T10:38:39Z","timestamp":1612521519000},"page":"1016-1023","source":"Crossref","is-referenced-by-count":30,"title":["Smartphone electrocardiogram for detecting atrial fibrillation after a cerebral ischaemic event: a multicentre randomized controlled trial"],"prefix":"10.1093","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8179-2315","authenticated-orcid":false,"given":"Keng Tat","family":"Koh","sequence":"first","affiliation":[{"name":"Department of Cardiology, Sarawak Heart Centre, 3rd Roundabout, Samarahan Expressway, 94300 Kota Samarahan, Sarawak, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan Chung","family":"Law","sequence":"additional","affiliation":[{"name":"Department of Medicine, Neurology Unit, Sarawak General Hospital, Jalan Hospital, 93586 Kuching, Sarawak, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Win Moe","family":"Zaw","sequence":"additional","affiliation":[{"name":"Department of Medicine, Neurology Unit, Sarawak General Hospital, Jalan Hospital, 93586 Kuching, Sarawak, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana Hui Ping","family":"Foo","sequence":"additional","affiliation":[{"name":"Clinical Research Centre, Institute for Clinical Research, Sarawak General Hospital, Jalan Hospital, 93586 Kuching, Sarawak, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen Ting","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Sarawak Heart Centre, 3rd Roundabout, Samarahan Expressway, 94300 Kota Samarahan, Sarawak, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anderson","family":"Steven","sequence":"additional","affiliation":[{"name":"Department of Medicine, Neurology Unit, Sarawak General Hospital, Jalan Hospital, 93586 Kuching, Sarawak, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Desmond","family":"Samuel","sequence":"additional","affiliation":[{"name":"Department of Medicine, Miri Hospital, Jalan Cahaya, 98000 Miri, Sarawak, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tem Lom","family":"Fam","sequence":"additional","affiliation":[{"name":"Department of Medicine, Miri Hospital, Jalan Cahaya, 98000 Miri, Sarawak, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching Hua","family":"Chai","sequence":"additional","affiliation":[{"name":"Department of Medicine, Miri Hospital, Jalan Cahaya, 98000 Miri, Sarawak, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhai Sing","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Medicine, Miri Hospital, Jalan Cahaya, 98000 Miri, Sarawak, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sivaraj","family":"Xaviar","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Sarawak Heart Centre, 3rd Roundabout, Samarahan Expressway, 94300 Kota Samarahan, Sarawak, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandan Deepak","family":"Bhavnani","sequence":"additional","affiliation":[{"name":"Department of Medicine, Bintulu Hospital, Jalan Bukit Nyabau, 97000 Bintulu, Sarawak, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason Seng Hong","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Medicine, Bintulu Hospital, Jalan Bukit Nyabau, 97000 Bintulu, Sarawak, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yen Yee","family":"Oon","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Sarawak Heart Centre, 3rd Roundabout, Samarahan Expressway, 94300 Kota Samarahan, Sarawak, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asri","family":"Said","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Sarawak Heart Centre, 3rd Roundabout, Samarahan Expressway, 94300 Kota Samarahan, 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Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,3,30]]},"reference":[{"key":"2021081005504613000_euab036-B1","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1161\/CIRCULATIONAHA.113.005119","article-title":"Worldwide epidemiology of atrial fibrillation: a Global Burden of Disease 2010 Study","volume":"129","author":"Chugh","year":"2014","journal-title":"Circulation"},{"key":"2021081005504613000_euab036-B2","doi-asserted-by":"crossref","first-page":"2746","DOI":"10.1093\/eurheartj\/eht280","article-title":"Projections on the number of individuals with atrial fibrillation in the European Union, from 2000 to 2060","volume":"34","author":"Krijthe","year":"2013","journal-title":"Eur Heart J"},{"key":"2021081005504613000_euab036-B3","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0167-5273(03)00031-7","article-title":"Admissions with atrial fibrillation in a multiracial population in Kuala 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The SEARCH-AF study","volume":"111","author":"Lowres","year":"2014","journal-title":"Thromb Haemost"},{"key":"2021081005504613000_euab036-B11","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1136\/heartjnl-2016-309993","article-title":"Screening for atrial fibrillation in 13 122 Hong Kong citizens with smartphone electrocardiogram","volume":"103","author":"Chan","year":"2017","journal-title":"Heart"},{"key":"2021081005504613000_euab036-B12","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.ijcard.2019.11.051","article-title":"Feasibility of outpatient smartphone electrocardiogram after a cerebral ischemic event","volume":"297","author":"Koh","year":"2019","journal-title":"Int J Cardiol"},{"key":"2021081005504613000_euab036-B13","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/j.amjcard.2015.06.012","article-title":"A comparison of atrial fibrillation monitoring strategies after cryptogenic stroke (from the cryptogenic stroke and underlying AF trial)","volume":"116","author":"Choe","year":"2015","journal-title":"Am J Cardiol"},{"key":"2021081005504613000_euab036-B14","doi-asserted-by":"crossref","first-page":"e006834","DOI":"10.1161\/CIRCEP.118.006834","article-title":"Smartwatch performance for the detection and quantification of atrial fibrillation","volume":"12","author":"Wasserlauf","year":"2019","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2021081005504613000_euab036-B15","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1056\/NEJMoa1901183","article-title":"Large-scale assessment of a smartwatch to identify atrial fibrillation","volume":"381","author":"Perez","year":"2019","journal-title":"N Engl J Med"}],"container-title":["EP Europace"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/europace\/article-pdf\/23\/7\/1016\/39622746\/euab036.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/europace\/article-pdf\/23\/7\/1016\/39622746\/euab036.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,10]],"date-time":"2021-08-10T01:51:35Z","timestamp":1628560295000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/europace\/article\/23\/7\/1016\/6199914"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,30]]},"references-count":15,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2021,3,30]]},"published-print":{"date-parts":[[2021,7,18]]}},"URL":"https:\/\/doi.org\/10.1093\/europace\/euab036","relation":{},"ISSN":["1099-5129","1532-2092"],"issn-type":[{"value":"1099-5129","type":"print"},{"value":"1532-2092","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,7,1]]},"published":{"date-parts":[[2021,3,30]]}}}