{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T01:55:32Z","timestamp":1780451732767,"version":"3.54.1"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2021,10,14]],"date-time":"2021-10-14T00:00:00Z","timestamp":1634169600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100004166","name":"Medical University of Warsaw","doi-asserted-by":"publisher","award":["2M6\/PM1\/17"],"award-info":[{"award-number":["2M6\/PM1\/17"]}],"id":[{"id":"10.13039\/501100004166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Pre-excitation syndrome can lead to recurrent supraventricular tachycardias (SVTs) and carries a risk of sudden cardiac death (SCD). However, an underestimated consequence of antegrade conduction through an accessory pathway is fusion of intrinsic and accessory conduction that causes asynchronous activation and myocardial contraction that could be a cause for cardiac dysfunction and dilation. It is not known to what extent pre-excitation affects myocardial and physical performance in those patients. The aim of the study was to assess to what degree ventricular pre-excitation affects physical performance in children, using cardio-pulmonary exercise testing (CPET).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>The study group consisted of 30 asymptomatic children, aged 8\u201317\u2009years, with pre-excitation and no history or documentation of SVT compared to 31 healthy controls matched according to sex and age. All patients underwent routine cardiology assessment and then CPET. Echocardiography showed there were no differences in the left ventricular size and function between the study and control group. During the CPET both, patients and controls achieved maximal effort. Patients in the study group showed significantly lower values of VO2max and anaerobic threshold when compared to controls. The most affected subgroup was patients with persistent pre-excitation throughout the exercise.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Physical performance is affected in children with pre-excitation. This effect is stronger in patients with persistent delta wave observed throughout the exercise.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/europace\/euab171","type":"journal-article","created":{"date-parts":[[2021,6,25]],"date-time":"2021-06-25T19:13:02Z","timestamp":1624648382000},"page":"855-859","source":"Crossref","is-referenced-by-count":5,"title":["Assessment of the physical performance in children with asymptomatic pre-excitation"],"prefix":"10.1093","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6447-1261","authenticated-orcid":false,"given":"Tomasz M","family":"Ksi\u0105\u017cczyk","sequence":"first","affiliation":[{"name":"Department of Paediatric Cardiology and General Paediatrics, Medical University of Warsaw, 63A Zwirki i Wigury Street, 02-091 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Jaro\u0144","sequence":"additional","affiliation":[{"name":"Anna Jaro\u0144, My Royal Baby\u2014Physiotherapy. 27\/35\/4 Marsza\u0142kowska Street, 00-639 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rados\u0142aw","family":"Pietrzak","sequence":"additional","affiliation":[{"name":"Department of Paediatric Cardiology and General Paediatrics, Medical University of Warsaw, 63A Zwirki i Wigury Street, 02-091 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6416-4106","authenticated-orcid":false,"given":"Bo\u017cena","family":"Werner","sequence":"additional","affiliation":[{"name":"Department of Paediatric Cardiology and General Paediatrics, Medical University of Warsaw, 63A Zwirki i Wigury Street, 02-091 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,10,14]]},"reference":[{"key":"2022050518230184500_euab171-B1","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1056\/NEJM197911153012003","article-title":"Ventricular fibrillation in the Wolff-Parkinson-White syndrome","volume":"301","author":"Klein","year":"1979","journal-title":"N Engl J Med"},{"key":"2022050518230184500_euab171-B2","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1161\/01.CIR.53.2.249","article-title":"Alterations in ventricular contraction pattern in the Wolff-Parkinson-White syndrome. 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