{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T23:13:36Z","timestamp":1777418016385,"version":"3.51.4"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2021,12,23]],"date-time":"2021-12-23T00:00:00Z","timestamp":1640217600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology of Taiwan","doi-asserted-by":"publisher","award":["MOST 109\u20132314-B-010\u2013058-MY2"],"award-info":[{"award-number":["MOST 109\u20132314-B-010\u2013058-MY2"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"name":"TVGH","award":["V109D48-001-MY2-2, C19-027"],"award-info":[{"award-number":["V109D48-001-MY2-2, C19-027"]}]},{"DOI":"10.13039\/501100017231","name":"Research Foundation of Cardiovascular Medicine","doi-asserted-by":"publisher","award":["109\u201302-012"],"award-info":[{"award-number":["109\u201302-012"]}],"id":[{"id":"10.13039\/501100017231","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Szu-Yuan Research Foundation of Internal Medicine","award":["110001"],"award-info":[{"award-number":["110001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,7,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>For patients with typical and atypical atrial flutter (AFL) but without history of atrial fibrillation (AF), the long-term cardiovascular (CV) outcomes after catheter ablation for AFL remain unclear. We compared the long-term all-cause mortality and CV outcomes in patients with AFL receiving catheter ablation compared with the results with medical therapy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>Atrial flutter patients receiving catheter ablation for typical AFL were identified using the Health Insurance Database, and constituted the \u2018AFL ablation group\u2019. Patients with typical and atypical AFL but without ablation (AFL without ablation group) were propensity matched to the AFL ablation group. Patients with prior AF diagnosis were excluded. Primary outcomes included all-cause and CV mortality, heart failure (HF) hospitalization, and stroke. The multivariable cox hazards regression model was used to evaluate the hazard ratio (HR) for study outcomes. A total of 3784 AFL patients (1892 patients in each group) was studied. Their mean follow-up durations were 7.85 \u00b1 2.57 years (AFL without ablation group) and 8.31 \u00b1 4.53 years (AFL ablation group). Atrial flutter with ablation patients had lower risks of all-cause mortality (HR: 0.68, P &amp;lt; 0.001), CV deaths (HR: 0.78, P = 0.001), HF hospitalization (HR: 0.84, P = 0.01), and stroke (HR: 0.80, P = 0.01).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Catheter ablation for AFL in patients without prior AF was associated with lower risks of all-cause mortality and CV events compared with AFL patients without ablation during long-term follow-ups.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/europace\/euab308","type":"journal-article","created":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T20:21:27Z","timestamp":1638390087000},"page":"970-978","source":"Crossref","is-referenced-by-count":16,"title":["Long-term mortality and cardiovascular outcomes in patients with atrial flutter after catheter ablation"],"prefix":"10.1093","volume":"24","author":[{"given":"Dony","family":"Yugo","sequence":"first","affiliation":[{"name":"Heart Rhythm Center, Taipei Veterans General Hospital , Taipei, Taiwa"},{"name":"Cardiovascular Department, Faculty of Medicine, University of Indonesia , Jakarta , Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun Yu","family":"Chen","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center, Taipei Veterans General Hospital , Taipei, Taiwa"},{"name":"Institute of Epidemiology and Preventive Medicine College of Public Health, National Taiwan University , Taipei , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yenn Jiang","family":"Lin","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center, Taipei Veterans General Hospital , Taipei, Taiwa"},{"name":"Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University , Taipei and Hsinchu , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4979-8351","authenticated-orcid":false,"given":"Kuo Liong","family":"Chien","sequence":"additional","affiliation":[{"name":"Institute of Epidemiology and Preventive Medicine College of Public Health, National Taiwan University , Taipei , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shih Lin","family":"Chang","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center, Taipei Veterans General Hospital , Taipei, Taiwa"},{"name":"Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University , Taipei and Hsinchu , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li Wei","family":"Lo","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center, Taipei Veterans General Hospital , Taipei, Taiwa"},{"name":"Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University , Taipei and Hsinchu , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu Feng","family":"Hu","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center, Taipei Veterans General Hospital , Taipei, Taiwa"},{"name":"Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University , Taipei and Hsinchu , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tze Fan","family":"Chao","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center, Taipei Veterans General Hospital , Taipei, Taiwa"},{"name":"Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University , Taipei and Hsinchu , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fa Po","family":"Chung","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center, Taipei Veterans General Hospital , Taipei, Taiwa"},{"name":"Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University , Taipei and Hsinchu , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo Nan","family":"Liao","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center, Taipei Veterans General Hospital , Taipei, Taiwa"},{"name":"Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University , Taipei and Hsinchu , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ting Yung","family":"Chang","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center, Taipei Veterans General Hospital , Taipei, Taiwa"},{"name":"Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University , Taipei and Hsinchu , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chin Yu","family":"Lin","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center, Taipei Veterans General Hospital , Taipei, Taiwa"},{"name":"Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University , Taipei and Hsinchu , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ta Chuan","family":"Tuan","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center, Taipei Veterans General Hospital , Taipei, Taiwa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Kuo","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center, Taipei Veterans General Hospital , Taipei, Taiwa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng I","family":"Wu","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center, Taipei Veterans General Hospital , Taipei, Taiwa"},{"name":"Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University , Taipei and Hsinchu , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chih Min","family":"Liu","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center, Taipei Veterans General Hospital , Taipei, Taiwa"},{"name":"Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University , Taipei and Hsinchu , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shin Huei","family":"Liu","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center, Taipei Veterans General Hospital , Taipei, Taiwa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng Hung","family":"Li","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University , Taipei and Hsinchu , Taiwan"},{"name":"Cardiovascular Center, Taichung Veterans General Hospital , Taichung , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6218-7139","authenticated-orcid":false,"given":"Yu Cheng","family":"Hsieh","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University , Taipei and Hsinchu , Taiwan"},{"name":"Cardiovascular Center, Taichung Veterans General Hospital , Taichung , Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shih Ann","family":"Chen","sequence":"additional","affiliation":[{"name":"Heart Rhythm Center, Taipei Veterans General Hospital , Taipei, Taiwa"},{"name":"Faculty of Medicine and Institute of Clinical Medicine, National Yang Ming Chiao Tung University , Taipei and Hsinchu , Taiwan"},{"name":"Cardiovascular Center, Taichung Veterans General Hospital , Taichung , 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