{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T07:19:07Z","timestamp":1788506347493,"version":"build-2803163510"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2022,8,11]],"date-time":"2022-08-11T00:00:00Z","timestamp":1660176000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,10,13]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Sports practice, especially in competition, is usually restrained in patients diagnosed with long QT syndrome (LQTS). Although data are scarce, a low incidence of cardiac arrhythmic events (CAEs) during sports practice is reported. We aim to evaluate the incidence of CAE during sports practice in LQTS patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>All consecutive patients above 18 years of age diagnosed with LQTS and prospectively followed at the referral centre for inherited arrhythmia syndrome received a survey to retrospectively assess their sports practice prior to and after the diagnosis of LQTS. Two hundred and forty-six patients were included (57% females). The median age was 43 years, and the median QTc was 457\u2005ms (428; 482). Patients reported a total of 4092 years [1376 (34%) after diagnosis] of sports practice: 2905 (77%) [1138 (39%) after diagnosis] years of leisure practice and 1187 (23%) [238 (20%) after diagnosis] years of competitive practice. One hundred and eighty (73%) patients practiced sport prior to the diagnosis of LQTS and 170 (69%) after. Prior to the diagnosis, four (2%) patients presented a CAE during leisure sports practice and one during competition. After diagnosis, only one patient presented a CAE, appropriately treated by an implantable cardioverter defibrillator discharge, in the context of beta-blocker non-compliance. The CAE event rate was 0.0007 events\/year in the 1376 years of total sports practice after the diagnosis of LQTS.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>After the diagnosis of LQTS, the occurrence of CAE is very low during sports practice, even in competitive practice. There was no CAE in patients properly treated with beta-blocker therapy with good compliance.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/europace\/euac047","type":"journal-article","created":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T04:17:38Z","timestamp":1648181858000},"page":"1675-1683","source":"Crossref","is-referenced-by-count":4,"title":["Does sports participation increase risk in patients with long QT syndrome? Results from a large French cohort"],"prefix":"10.1093","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6353-8778","authenticated-orcid":false,"given":"Caroline","family":"Davydoff","sequence":"first","affiliation":[{"name":"Service de Cardiologie, L\u2019institut du thorax, CHU Nantes , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6848-5452","authenticated-orcid":false,"given":"Antoine","family":"Andorin","sequence":"additional","affiliation":[{"name":"Service de Cardiologie, L\u2019institut du thorax, CHU Nantes , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6418-6540","authenticated-orcid":false,"given":"Damien","family":"Minois","sequence":"additional","affiliation":[{"name":"Service de Cardiologie, L\u2019institut du thorax, CHU Nantes , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0950-2624","authenticated-orcid":false,"given":"Marine","family":"Arnaud","sequence":"additional","affiliation":[{"name":"Service de Cardiologie, L\u2019institut du thorax, CHU Nantes , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathilde","family":"Minier","sequence":"additional","affiliation":[{"name":"Service de Cardiologie, L\u2019institut du thorax, CHU Nantes , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Sacher","sequence":"additional","affiliation":[{"name":"Service de Cardiologie, CHU de Bordeaux , Bordeaux , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raphael","family":"Martins","sequence":"additional","affiliation":[{"name":"Service de Cardiologie et Maladies Vasculaires, CHU Rennes , Rennes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7415-0787","authenticated-orcid":false,"given":"Nicolas","family":"Clementy","sequence":"additional","affiliation":[{"name":"Service de Cardiologie, Centre Hospitalier Universitaire Trousseau et Facult\u00e9 de M\u00e9decine, Universit\u00e9 Fran\u00e7ois Rabelais , Tours , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Baptiste","family":"Gourraud","sequence":"additional","affiliation":[{"name":"Service de Cardiologie, L\u2019institut du thorax, CHU Nantes , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Probst","sequence":"additional","affiliation":[{"name":"Service de Cardiologie, L\u2019institut du thorax, CHU Nantes , Nantes , France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,8,11]]},"reference":[{"key":"2022101319385548700_euac047-B1","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1161\/CIRCULATIONAHA.109.863209","article-title":"Prevalence of the congenital long-QT syndrome","volume":"120","author":"Schwartz","year":"2009","journal-title":"Circulation"},{"key":"2022101319385548700_euac047-B2","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1161\/01.CIR.103.1.89","article-title":"Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias","volume":"103","author":"Schwartz","year":"2001","journal-title":"Circulation"},{"key":"2022101319385548700_euac047-B3","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1136\/bjsports-2012-091751","article-title":"Return to play? 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