{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T08:37:30Z","timestamp":1792485450308,"version":"4.5.0"},"reference-count":192,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2022,8,11]],"date-time":"2022-08-11T00:00:00Z","timestamp":1660176000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,12,9]]},"DOI":"10.1093\/europace\/euac125","type":"journal-article","created":{"date-parts":[[2022,8,11]],"date-time":"2022-08-11T13:45:56Z","timestamp":1660225556000},"page":"1981-2003","source":"Crossref","is-referenced-by-count":253,"title":["EHRA expert consensus statement on arrhythmic mitral valve prolapse and mitral annular disjunction complex in collaboration with the ESC Council on valvular heart disease and the European Association of Cardiovascular Imaging endorsed cby the Heart Rhythm Society, by the Asia Pacific Heart Rhythm Society, and by the Latin American Heart Rhythm Society"],"prefix":"10.1093","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4295-6679","authenticated-orcid":false,"given":"Avi","family":"Sabbag","sequence":"first","affiliation":[{"name":"The Davidai Center for Rhythm Disturbances and Pacing, Chaim Sheba Medical Center , Tel Hashomer 52621 ,","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7116-5529","authenticated-orcid":false,"given":"Benjamin","family":"Essayagh","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Simone Veil Hospital , Cannes 06400 ,","place":["France"]},{"name":"Department of Cardiovascular Medicine, Mayo Clinic , Rochester 55905, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan David Ram\u00edrez","family":"Barrera","sequence":"additional","affiliation":[{"name":"Cardiologist Electrophysiologist, Cardiovid Clinic, Medellin , Colombia 050034, South America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0195-9753","authenticated-orcid":false,"given":"Cristina","family":"Basso","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Cardio-Toraco-Vascolari e Sanit\u00e0 Pubblica, Universit\u00e0 degli Studi di Padova , Padova 35128 ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9705-8142","authenticated-orcid":false,"given":"Ana","family":"Berni","sequence":"additional","affiliation":[{"name":"Cardiology and Cardiac Electrophysiology, EP Lab. Hospital Angeles Pedregal. Mexico City 10700, Board member, Mexican Society of Cardiology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9419-8019","authenticated-orcid":false,"given":"Bernard","family":"Cosyns","sequence":"additional","affiliation":[{"name":"Cardiology Department, Centrum voor hart en vaatziekten, Universitair Ziekenhuis Brussel, Free University of Brussels , Brussels 1090 ,","place":["Belgium"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Claude","family":"Deharo","sequence":"additional","affiliation":[{"name":"Department of Cardiology, L\u2019h\u00f4pital de la Timone , Marseille, 13005 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1379-1684","authenticated-orcid":false,"given":"Thomas","family":"Deneke","sequence":"additional","affiliation":[{"name":"Clinic for Interventional Electrophysiology, Heart Center RH\u00d6N-KLINIKUM Campus Bad Neustadt , 97616 ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Di Biase","sequence":"additional","affiliation":[{"name":"Albert Einstein College of Medicine at Montefiore Hospital , New York, NY 10467 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0910-5450","authenticated-orcid":false,"given":"Maurice","family":"Enriquez-Sarano","sequence":"additional","affiliation":[{"name":"Minneapolis Heart Institute , Minneapolis, MN 55407 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2677-3389","authenticated-orcid":false,"given":"Erwan","family":"Donal","sequence":"additional","affiliation":[{"name":"Service de Cardiologie, CCP-CHU Pontchaillou , Rennes 35033 ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8080-5698","authenticated-orcid":false,"given":"Katsuhiko","family":"Imai","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, National Hospital Organization Kure Medical Center and Chugoku Cancer Center , Hiroshima 737-0023 ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han S","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Austin and Northern Health, University of Melbourne , Melbourne 3010 ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7208-5769","authenticated-orcid":false,"given":"Nina Ajmone","family":"Marsan","sequence":"additional","affiliation":[{"name":"Leiden University Medical Center, Cardiology , Leiden 2333 ,","place":["Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohit K","family":"Turagam","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai , New York, NY 10029 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5625-0071","authenticated-orcid":false,"given":"Petr","family":"Peichl","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Institute for Clinical and Experimental Medicine (IKEM) , Prague 73117 ,","place":["Czech Republic"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunny S","family":"Po","sequence":"additional","affiliation":[{"name":"Heart Rhythm Institute and Section of Cardiovascular Diseases, University of Oklahoma Health Sciences Center , Oklahoma City, OK 0372 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4900-0453","authenticated-orcid":false,"given":"Kristina Hermann","family":"Haugaa","sequence":"additional","affiliation":[{"name":"ProCardio Center for Innovation, Department of Cardiology, Oslo University Hospital , Rikshospitalet, Oslo ,","place":["Norway"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dipen","family":"Shah","sequence":"additional","affiliation":[{"name":"Cantonal Hospital, Cardiology Department , CH-1211 Geneva ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"de Riva Silva","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Leiden University Medical Center , Leiden 2333 ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Bertrand","sequence":"additional","affiliation":[{"name":"Ziekenhuis Oost-Limburg, Hasselt University , Genk, Hasselt 3600 ,","place":["Belgium"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdi","family":"Saba","sequence":"additional","affiliation":[{"name":"Consultant and Reader in Cardiac Electrophysiology, Director, Advanced Ventricular Arrhythmia Training and Research Program, St. George\u2019s Hospital NHS Foundation Trust, St. George\u2019s, University of London , SW17 0QT ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Dweck","sequence":"additional","affiliation":[{"name":"Centre for cardiovascular science, University of Edinburgh , EH16 4TJ ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago Nava","family":"Townsend","sequence":"additional","affiliation":[{"name":"Instituto Nacional De Cardiologia Ich, Electrophysiology Department , Mexico Df 14080 ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tachapong","family":"Ngarmukos","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Ramathibodi Hospital, Mahidol University , Bangkok 73170 ,","place":["Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilherme","family":"Fenelon","sequence":"additional","affiliation":[{"name":"Coordenador - Centro de Arritmia, Hospital Israelita Albert Einstein , S\u00e3o Paulo - SP, 05652-900 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pasquale","family":"Santangeli","sequence":"additional","affiliation":[{"name":"Hospital of the University of Pennsylvania , Philadelphia, PA 19104 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leyla Elif","family":"Sade","sequence":"additional","affiliation":[{"name":"University of Pittsburgh, UPMC, Heart and Vascular Institute , ittsburgh, PA 15219 ,","place":["USA"]},{"name":"C.H.U. du Sart-Tilman, Universite de Liege , Liege 4000 ,","place":["Belgium"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Corrado","sequence":"additional","affiliation":[{"name":"Full Professor of Cardiovascular Medicine, Director, Inherited Arrhythmogenic Cardiomyopathies and Sports Cardiology Unit, Dept. of Cardiac, Thoracic and Vascular Sciences, University of Padua Medical School , Padova 35122 ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pier","family":"Lambiase","sequence":"additional","affiliation":[{"name":"UCL & Barts Heart Centre, Co-Director of Cardiovascular Research Barts NHS Trust, Inherited Arrhythmia Clinical Lead, UCL MRC DTP Theme Lead, BHRS Committee Research Lead, Institute of Cardiovascular Science, UCL, Department of Cardiology, Barts Heart Centre \u00a0 E1 1BB ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prashanthan","family":"Sanders","sequence":"additional","affiliation":[{"name":"Centre for Heart Rhythm Disorders, University of Adelaide , South Australia 5000 ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etienne","family":"Delacr\u00e9taz","sequence":"additional","affiliation":[{"name":"Clinique Cecil Hirslanden Lausanne & University Hospital Fribourg, Cardiology \u00a0 1003 ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arshad","family":"Jahangir","sequence":"additional","affiliation":[{"name":"University of Wisconsin School of Medicine and Public Health, Milwaukee, MI 53705, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth S","family":"Kaufman","sequence":"additional","affiliation":[{"name":"Clinical Electrophysiologist, MetroHealth Medical Center, Professor, Case Western Reserve University \u00a0 44106 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daljeet Kaur","family":"Saggu","sequence":"additional","affiliation":[{"name":"Consultant Cardiologist and Electrophysiologist, AIG HOSPITAL , Hyderabad 500032 ,","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc","family":"Pierard","sequence":"additional","affiliation":[{"name":"C.H.U. du Sart-Tilman, Universite de Liege , Liege 4000 ,","place":["Belgium"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Delgado","sequence":"additional","affiliation":[{"name":"Heart Institute, Hospital University Germans Trias i Pujol , Badalona 08916 ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrizio","family":"Lancellotti","sequence":"additional","affiliation":[{"name":"C.H.U. du Sart-Tilman, Universite de Liege , Liege 4000 ,","place":["Belgium"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,8,11]]},"reference":[{"key":"2026080913413607000_euac125-B1","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/S0140-6736(06)69208-8","article-title":"Burden of valvular heart diseases: a population-based study","volume":"368","author":"Nkomo","year":"2006","journal-title":"Lancet"},{"key":"2026080913413607000_euac125-B2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1056\/NEJM199907013410101","article-title":"Prevalence and clinical outcome of mitral-valve prolapse","volume":"341","author":"Freed","year":"1999","journal-title":"N Engl J Med"},{"key":"2026080913413607000_euac125-B3","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/S0002-8703(99)70151-1","article-title":"Anthropometric and physiologic correlates of mitral valve prolapse in a biethnic cohort of young adults: the CARDIA study","volume":"138","author":"Flack","year":"1999","journal-title":"Am Heart J"},{"key":"2026080913413607000_euac125-B4","first-page":"511","article-title":"Prevalence of mitral valve prolapse in ethnic groups","volume":"20","author":"Theal","year":"2004","journal-title":"Can J Cardiol"},{"key":"2026080913413607000_euac125-B5","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1161\/01.CIR.75.4.756","article-title":"The relationship of mitral annular shape to the diagnosis of mitral valve prolapse","volume":"75","author":"Levine","year":"1987","journal-title":"Circulation"},{"key":"2026080913413607000_euac125-B6","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1093\/eurheartj\/ehx391","article-title":"2017 ESC\/EACTS Guidelines for the management of valvular heart disease","volume":"38","author":"Baumgartner","year":"2017","journal-title":"Eur Heart J"},{"key":"2026080913413607000_euac125-B7","first-page":"CIR0000000000000923","article-title":"2020 ACC\/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association joint committee on clinical practice guidelines","author":"Otto","year":"2020","journal-title":"Circulation"},{"key":"2026080913413607000_euac125-B8","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1161\/CIRCULATIONAHA.118.034075","article-title":"Mitral valve prolapse, ventricular arrhythmias, and sudden death","volume":"140","author":"Basso","year":"2019","journal-title":"Circulation"},{"key":"2026080913413607000_euac125-B9","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/0735-1097(88)90164-7","article-title":"Long-term follow-up of idiopathic mitral valve prolapse in 300 patients: a prospective study","volume":"11","author":"Duren","year":"1988","journal-title":"J Am Coll Cardiol"},{"key":"2026080913413607000_euac125-B10","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/j.jacep.2021.01.007","article-title":"Antemortem and post-mortem characteristics of lethal mitral valve prolapse among all countywide sudden deaths","volume":"7","author":"Delling","year":"2021","journal-title":"JACC Clin Electrophysiol"},{"key":"2026080913413607000_euac125-B11","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1161\/CIRCULATIONAHA.115.016291","article-title":"Arrhythmic mitral valve prolapse and sudden cardiac death","volume":"132","author":"Basso","year":"2015","journal-title":"Circulation"},{"key":"2026080913413607000_euac125-B12","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1111\/echo.15299","article-title":"Definition, prevalence, and clinical significance of mitral annular disjunction in different patient cohorts: a systematic review","volume":"39","author":"Bennett","year":"2022","journal-title":"Echocardiography"},{"key":"2026080913413607000_euac125-B13","first-page":"e005030","article-title":"Morphofunctional abnormalities of mitral annulus and arrhythmic mitral valve prolapse","volume":"9","author":"Marra M","year":"2016","journal-title":"Circ Cardiovasc Imaging"},{"key":"2026080913413607000_euac125-B14","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.jacc.2020.06.029","article-title":"Presentation and outcome of arrhythmic mitral valve prolapse","volume":"76","author":"Essayagh","year":"2020","journal-title":"J Am Coll Cardiol"},{"key":"2026080913413607000_euac125-B15","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1016\/j.jcmg.2021.04.029","article-title":"The mitral annular disjunction of mitral valve prolapse: presentation and outcome","volume":"14","author":"Essayagh","year":"2021","journal-title":"JACC Cardiovasc Imaging"},{"key":"2026080913413607000_euac125-B16","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1001\/jamacardio.2020.1412","article-title":"Association between malignant mitral valve prolapse and sudden cardiac death: a review","volume":"5","author":"Muthukumar","year":"2020","journal-title":"JAMA Cardiol"},{"key":"2026080913413607000_euac125-B17","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1016\/S0735-1097(98)90059-6","article-title":"Reconsideration of echocardiographic standards for mitral valve prolapse: lack of association between leaflet displacement isolated to the apical four chamber view and independent echocardiographic evidence of abnormality","volume":"11","author":"Levine","year":"1988","journal-title":"J Am Coll Cardiol"},{"key":"2026080913413607000_euac125-B18","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1111\/jce.13374","article-title":"Imaging characteristics of papillary muscle site of origin of ventricular arrhythmias in patients with mitral valve prolapse","volume":"29","author":"Fulton","year":"2018","journal-title":"J Cardiovasc Electrophysiol"},{"key":"2026080913413607000_euac125-B19","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1093\/eurheartj\/ehq222","article-title":"Degenerative mitral valve regurgitation: best practice revolution","volume":"31","author":"Adams","year":"2010","journal-title":"Eur Heart J"},{"key":"2026080913413607000_euac125-B20","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1093\/eurheartj\/ehab395","article-title":"2021 ESC\/EACTS guidelines for the management of valvular heart disease","volume":"43","author":"Vahanian","year":"2021","journal-title":"Eur Heart J"},{"key":"2026080913413607000_euac125-B21","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S0140-6736(05)17869-6","article-title":"Mitral valve prolapse","volume":"365","author":"Hayek","year":"2005","journal-title":"Lancet"},{"key":"2026080913413607000_euac125-B22","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1161\/CIRCULATIONAHA.117.033395","article-title":"Prevalence and clinical outcome of athletes with mitral valve prolapse","volume":"137","author":"Caselli","year":"2018","journal-title":"Circulation"},{"key":"2026080913413607000_euac125-B23","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1161\/CIRCULATIONAHA.114.012594","article-title":"Familial clustering of mitral valve prolapse in the community","volume":"131","author":"Delling","year":"2015","journal-title":"Circulation"},{"key":"2026080913413607000_euac125-B24","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/0002-9343(83)90791-X","article-title":"Inheritance of the mitral valve prolapse syndrome. Discussion of a three-dimensional penetrance model","volume":"74","author":"Strahan","year":"1983","journal-title":"Am J Med"},{"key":"2026080913413607000_euac125-B25","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1056\/NEJM198511213132101","article-title":"Echocardiographically documented mitral-valve prolapse. Long-term follow-up of 237 patients","volume":"313","author":"Nishimura","year":"1985","journal-title":"N Engl J Med"},{"key":"2026080913413607000_euac125-B26","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.pcad.2020.03.004","article-title":"Floppy mitral valve\/mitral valve prolapse: a complex entity with multiple genotypes and phenotypes","volume":"63","author":"Boudoulas","year":"2020","journal-title":"Prog Cardiovasc Dis"},{"key":"2026080913413607000_euac125-B27","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1093\/eurheartj\/ehx505","article-title":"New insights into mitral valve dystrophy: a Filamin-A genotype-phenotype and outcome study","volume":"39","author":"Le Tourneau","year":"2018","journal-title":"Eur Heart J"},{"key":"2026080913413607000_euac125-B28","doi-asserted-by":"crossref","first-page":"e002497","DOI":"10.1161\/CIRCGEN.119.002497","article-title":"Genome-wide association study-driven gene-set analyses, genetic, and functional follow-up suggest glis1 as a susceptibility gene for mitral valve prolapse","volume":"12","author":"Yu","year":"2019","journal-title":"Circ Genom Precis Med"},{"key":"2026080913413607000_euac125-B29","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1038\/ng.3383","article-title":"Genetic association analyses highlight biological pathways underlying mitral valve prolapse","volume":"47","author":"Dina","year":"2015","journal-title":"Nat Genet"},{"key":"2026080913413607000_euac125-B30","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1161\/01.CIR.0000028933.34260.09","article-title":"Natural history of asymptomatic mitral valve prolapse in the community","volume":"106","author":"Avierinos","year":"2002","journal-title":"Circulation"},{"key":"2026080913413607000_euac125-B31","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1016\/S0735-1097(02)02161-7","article-title":"Mitral valve prolapse in the general population: the benign nature of echocardiographic features in the Framingham Heart Study","volume":"40","author":"Freed","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"2026080913413607000_euac125-B32","first-page":"1097","article-title":"Sudden death in young people with apparently isolated mitral valve prolapse [comment] [see comments]","volume":"27","author":"Corrado","year":"1997","journal-title":"G Ital Cardiol"},{"key":"2026080913413607000_euac125-B33","doi-asserted-by":"crossref","DOI":"10.1016\/0002-8703(87)90958-6","article-title":"Arrhythmias and sudden death in mitral valve prolapse","volume":"113","author":"Kligfield","year":"1987","journal-title":"Am Heart J"},{"key":"2026080913413607000_euac125-B34","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1016\/S0735-1097(99)00474-X","article-title":"Sudden death in mitral regurgitation due to flail leaflet","volume":"34","author":"Grigioni","year":"1999","journal-title":"J Am Coll Cardiol"},{"key":"2026080913413607000_euac125-B35","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/0002-9149(92)91281-8","article-title":"Comparison of cardiac findings in patients with mitral valve prolapse who die suddenly to those who have congestive heart failure from mitral regurgitation and to those with non-fatal cardiac conditions","volume":"70","author":"Farb","year":"1992","journal-title":"Am J Cardiol"},{"key":"2026080913413607000_euac125-B36","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.hrthm.2015.09.026","article-title":"Mitral valve prolapse and sudden cardiac arrest in the community","volume":"13","author":"Narayanan","year":"2016","journal-title":"Heart Rhythm"},{"key":"2026080913413607000_euac125-B37","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1161\/CIRCULATIONAHA.118.033488","article-title":"Common phenotype in patients with mitral valve prolapse who experienced sudden cardiac death","volume":"138","author":"Hourdain","year":"2018","journal-title":"Circulation"},{"key":"2026080913413607000_euac125-B38","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1136\/heartjnl-2017-312932","article-title":"Mitral valve prolapse and sudden cardiac death: a systematic review and meta-analysis","volume":"105","author":"Nalliah","year":"2019","journal-title":"Heart"},{"key":"2026080913413607000_euac125-B39","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1136\/heartjnl-2019-314788","article-title":"Mechanical dispersion and arrhythmic mitral valve prolapse: substrate and trigger in electrical instability","volume":"105","author":"Marra M","year":"2019","journal-title":"Heart"},{"key":"2026080913413607000_euac125-B40","doi-asserted-by":"crossref","first-page":"e254","DOI":"10.1161\/CIR.0000000000000950","article-title":"Heart disease and stroke statistics-2021 update: a report from the American Heart Association","volume":"143","author":"Virani","year":"2021","journal-title":"Circulation"},{"key":"2026080913413607000_euac125-B41","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1093\/ehjci\/jez153","article-title":"Anatomy of mitral annulus insights from non-invasive imaging techniques","volume":"20","author":"Faletra","year":"2019","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2026080913413607000_euac125-B42","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1007\/s12574-017-0349-1","article-title":"The analysis of mitral annular disjunction detected by echocardiography and comparison with previously reported pathological data","volume":"15","author":"Konda","year":"2017","journal-title":"J Echocardiogr"},{"key":"2026080913413607000_euac125-B43","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1016\/j.echo.2005.06.013","article-title":"Mitral annular disjunction in advanced myxomatous mitral valve disease: echocardiographic detection and surgical correction","volume":"18","author":"Eriksson","year":"2005","journal-title":"J Am Soc Echocardiogr"},{"key":"2026080913413607000_euac125-B44","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/1476-7120-8-53","article-title":"Mitral annular disjunction in myxomatous mitral valve disease: a relevant abnormality recognizable by transthoracic echocardiography","volume":"8","author":"Carmo","year":"2010","journal-title":"Cardiovasc Ultrasound"},{"key":"2026080913413607000_euac125-B45","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1136\/heartjnl-2020-317330","article-title":"Multimodality imaging assessment of mitral annular disjunction in mitral valve prolapse","volume":"107","author":"Mantegazza","year":"2020","journal-title":"Heart"},{"key":"2026080913413607000_euac125-B46","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1016\/j.jacc.2018.07.070","article-title":"The mitral annulus disjunction arrhythmic syndrome","volume":"72","author":"Dejgaard","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"2026080913413607000_euac125-B47","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1016\/j.amjcard.2019.08.047","article-title":"Usefulness of 3-tesla cardiac magnetic resonance to detect mitral annular disjunction in patients with mitral valve prolapse","volume":"124","author":"Essayagh","year":"2019","journal-title":"Am J Cardiol"},{"key":"2026080913413607000_euac125-B48","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1007\/s10554-020-01818-4","article-title":"Prevalence of mitral annular disjunction in patients with mitral valve prolapse and severe regurgitation","volume":"36","author":"Putnam","year":"2020","journal-title":"Int J Cardiovasc Imaging"},{"key":"2026080913413607000_euac125-B49","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1093\/ehjci\/jeab022","article-title":"Prevalence and extent of mitral annular disjunction in structurally normal hearts: comprehensive 3D analysis using cardiac computed tomography","volume":"22","author":"Toh","year":"2021","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2026080913413607000_euac125-B50","doi-asserted-by":"crossref","first-page":"e005971","DOI":"10.1161\/CIRCIMAGING.116.005971","article-title":"Pathophysiology of degenerative mitral regurgitation: new 3-dimensional imaging insights","volume":"11","author":"Antoine","year":"2018","journal-title":"Circ Cardiovasc Imaging"},{"key":"2026080913413607000_euac125-B51","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1016\/j.jcmg.2017.03.001","article-title":"Mitral annular disjunction: the forgotten component of myxomatous mitral valve disease","volume":"10","author":"Enriquez-Sarano","year":"2017","journal-title":"JACC Cardiovasc Imaging"},{"key":"2026080913413607000_euac125-B52","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcmg.2021.01.028","article-title":"Tricuspid annulus disjunction: novel findings by cardiac magnetic resonance in patients with mitral annulus disjunction","author":"Aabel","year":"2021","journal-title":"JACC Cardiovasc Imaging"},{"key":"2026080913413607000_euac125-B53","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1093\/icvts\/ivaa304","article-title":"Evolution from mitral annular dysfunction to severe mitral regurgitation in Barlow\u2019s disease","volume":"32","author":"Hiemstra","year":"2021","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"2026080913413607000_euac125-B54","article-title":"Mitral annular disjunction of degenerative mitral regurgitation: 3D evaluation and implications for mitral repair","author":"Essayagh","year":"2021","journal-title":"J Am Soc Echocardiogr"},{"key":"2026080913413607000_euac125-B55","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1056\/NEJM198602273140902","article-title":"The association of floppy mitral valve with disjunction of the mitral annulus fibrosus","volume":"314","author":"Hutchins","year":"1986","journal-title":"N Engl J Med"},{"key":"2026080913413607000_euac125-B56","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/0002-8703(81)90235-0","article-title":"The conduction system in mitral valve prolapse syndrome with sudden death","volume":"101","author":"Bharati","year":"1981","journal-title":"Am Heart J"},{"key":"2026080913413607000_euac125-B57","doi-asserted-by":"crossref","first-page":"e010584","DOI":"10.1161\/JAHA.118.010584","article-title":"Mitral valve prolapse and sudden cardiac death: a systematic review","volume":"7","author":"Han","year":"2018","journal-title":"J Am Heart Assoc"},{"key":"2026080913413607000_euac125-B58","doi-asserted-by":"crossref","first-page":"e015587","DOI":"10.1161\/JAHA.119.015587","article-title":"Characteristic histopathological findings and cardiac arrest rhythm in isolated mitral valve prolapse and sudden cardiac death","volume":"9","author":"Han","year":"2020","journal-title":"J Am Heart Assoc"},{"key":"2026080913413607000_euac125-B59","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1161\/CIRCULATIONAHA.112.118083","article-title":"Quantitative analysis of mitral valve morphology in mitral valve prolapse with real-time 3-dimensional echocardiography: importance of annular saddle shape in the pathogenesis of mitral regurgitation","volume":"127","author":"Lee","year":"2013","journal-title":"Circulation"},{"key":"2026080913413607000_euac125-B60","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1136\/hrt.59.6.712","article-title":"A histological study of the atrioventricular junction in hearts with normal and prolapsed leaflets of the mitral valve","volume":"59","author":"Angelini","year":"1988","journal-title":"Br Heart J"},{"key":"2026080913413607000_euac125-B61","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcmg.2019.06.021","article-title":"Mitral annular disjunction in a large cohort of patients with mitral valve prolapse and significant regurgitation","author":"Mantegazza","year":"2019","journal-title":"JACC Cardiovasc Imaging"},{"key":"2026080913413607000_euac125-B62","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1016\/j.jcmg.2016.11.022","article-title":"Functional implication of mitral annular disjunction in mitral valve prolapse: a quantitative dynamic 3d echocardiographic study","volume":"10","author":"Lee","year":"2017","journal-title":"JACC Cardiovasc Imaging"},{"key":"2026080913413607000_euac125-B63","first-page":"19S","article-title":"Assessment of mitral annular disjunction by cardiac MRI in patients with mitral valve prolapse","author":"Christiansen JP","year":"2010","journal-title":"Heart Lung Circ"},{"key":"2026080913413607000_euac125-B64","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1111\/echo.14437","article-title":"Mitral annular disjunction: a systematic review of the literature","volume":"36","author":"Bennett","year":"2019","journal-title":"Echocardiography"},{"key":"2026080913413607000_euac125-B65","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1111\/echo.14896","article-title":"Mitral annular disjunction in patients with primary severe mitral regurgitation and mitral valve prolapse","volume":"37","author":"Konda","year":"2020","journal-title":"Echocardiography"},{"key":"2026080913413607000_euac125-B66","doi-asserted-by":"crossref","DOI":"10.1001\/jamacardio.2021.2312","article-title":"Association of mitral annular disjunction with cardiovascular outcomes among patients with marfan syndrome","author":"Demolder","year":"2021","journal-title":"JAMA Cardiol"},{"key":"2026080913413607000_euac125-B67","article-title":"Mitral annulus disjunction is associated with adverse outcome in Marfan and Loeys-Dietz syndromes","author":"Chivulescu","year":"2020","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2026080913413607000_euac125-B68","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1161\/CIRCULATIONAHA.117.033173","article-title":"Clinical outcome of degenerative mitral regurgitation: critical importance of echocardiographic quantitative assessment in routine practice","volume":"138","author":"Antoine","year":"2018","journal-title":"Circulation"},{"key":"2026080913413607000_euac125-B69","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1056\/NEJMoa041451","article-title":"Quantitative determinants of the outcome of asymptomatic mitral regurgitation","volume":"352","author":"Enriquez-Sarano","year":"2005","journal-title":"N Engl J Med"},{"key":"2026080913413607000_euac125-B70","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1093\/eurheartj\/ehm199","article-title":"Left atrial remodelling in mitral regurgitation\u2013methodologic approach, physiological determinants, and outcome implications: a prospective quantitative Doppler-echocardiographic and electron beam-computed tomographic study","volume":"28","author":"Messika-Zeitoun","year":"2007","journal-title":"Eur Heart J"},{"key":"2026080913413607000_euac125-B71","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.jacc.2010.02.059","article-title":"Impact of left atrial volume on clinical outcome in organic mitral regurgitation","volume":"56","author":"Le Tourneau","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"2026080913413607000_euac125-B72","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.jacc.2019.06.032","article-title":"Prognostic implications of left atrial enlargement in degenerative mitral regurgitation","volume":"74","author":"Essayagh","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"2026080913413607000_euac125-B73","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.jacc.2018.10.067","article-title":"Long-term implications of atrial fibrillation in patients with degenerative mitral regurgitation","volume":"73","author":"Grigioni","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"2026080913413607000_euac125-B74","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.jacc.2013.02.060","article-title":"Malignant bileaflet mitral valve prolapse syndrome in patients with otherwise idiopathic out-of-hospital cardiac arrest","volume":"62","author":"Sriram","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"2026080913413607000_euac125-B75","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/0002-8703(83)90705-6","article-title":"Mitral valve prolapse in the general population. 2. Clinical features: the Framingham study","volume":"106","author":"Savage","year":"1983","journal-title":"Am Heart J"},{"key":"2026080913413607000_euac125-B76","doi-asserted-by":"crossref","first-page":"305","DOI":"10.7326\/0003-4819-111-4-305","article-title":"Mitral valve prolapse: causes, clinical manifestations, and management","volume":"111","author":"Devereux","year":"1989","journal-title":"Ann Intern Med"},{"key":"2026080913413607000_euac125-B77","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1136\/hrt.41.4.385","article-title":"Abnormal left ventricular wall movement in patients with chest pain and normal coronary arteriograms. Relation to inferior T wave changes and mitral prolapse","volume":"41","author":"Gibson","year":"1979","journal-title":"Br Heart J"},{"key":"2026080913413607000_euac125-B78","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1161\/CIRCULATIONAHA.115.017979","article-title":"The knot that binds mitral valve prolapse and sudden cardiac death","volume":"132","author":"Noseworthy","year":"2015","journal-title":"Circulation"},{"key":"2026080913413607000_euac125-B79","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/0002-9149(92)91287-E","article-title":"Electrocardiographic abnormalities in mitral valve prolapse","volume":"70","author":"Bhutto","year":"1992","journal-title":"Am J Cardiol"},{"key":"2026080913413607000_euac125-B80","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1378\/chest.81.5.620","article-title":"Analysis of QT interval in patients with idiopathic mitral valve prolapse","volume":"81","author":"Bekheit","year":"1982","journal-title":"Chest"},{"key":"2026080913413607000_euac125-B81","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1016\/0002-8703(87)90956-2","article-title":"Prevalence and clinical features of mitral valve prolapse","volume":"113","author":"Levy","year":"1987","journal-title":"Am Heart J"},{"key":"2026080913413607000_euac125-B82","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1053\/eupc.2001.0186","article-title":"QT dispersion in patients with mitral valve prolapse is related to the echocardiographic degree of the prolapse and mitral leaflet thickness","volume":"3","author":"Zouridakis","year":"2001","journal-title":"Europace"},{"key":"2026080913413607000_euac125-B83","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1161\/01.CIR.73.5.1013","article-title":"Electrophysiologic effects of papillary muscle traction in the intact heart","volume":"73","author":"Gornick","year":"1986","journal-title":"Circulation"},{"key":"2026080913413607000_euac125-B84","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1161\/01.CIR.83.6.1888","article-title":"QTc prolongation measured by standard 12-lead electrocardiography is an independent risk factor for sudden death due to cardiac arrest","volume":"83","author":"Algra","year":"1991","journal-title":"Circulation"},{"key":"2026080913413607000_euac125-B85","doi-asserted-by":"crossref","first-page":"e005485","DOI":"10.1161\/CIRCEP.117.005485","article-title":"Association between QT-interval components and sudden cardiac death","volume":"10","author":"O\u2019Neal","year":"2017","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2026080913413607000_euac125-B86","doi-asserted-by":"crossref","first-page":"2495","DOI":"10.1161\/CIRCULATIONAHA.105.595892","article-title":"Significance of a fragmented QRS complex versus a Q wave in patients with coronary artery disease","volume":"113","author":"Das","year":"2006","journal-title":"Circulation"},{"key":"2026080913413607000_euac125-B87","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1016\/j.hrthm.2007.06.024","article-title":"Fragmented QRS on a 12-lead ECG: a predictor of mortality and cardiac events in patients with coronary artery disease","volume":"4","author":"Das","year":"2007","journal-title":"Heart Rhythm"},{"key":"2026080913413607000_euac125-B88","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.jjcc.2021.10.022","article-title":"Fragmented QRS as a predictor of cardiac events in patients with cardiac sarcoidosis","volume":"79","author":"Ogura","year":"2022","journal-title":"J Cardiol"},{"key":"2026080913413607000_euac125-B89","doi-asserted-by":"crossref","first-page":"e12507","DOI":"10.1111\/anec.12507","article-title":"Baseline fragmented QRS increases the risk of major arrhythmic events in Brugada syndrome: systematic review and meta-analysis","volume":"23","author":"Rattanawong","year":"2018","journal-title":"Ann Noninvasive Electrocardiol"},{"key":"2026080913413607000_euac125-B90","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.amjcard.2016.09.021","article-title":"Usefulness of fragmented QRS complexes in patients with congenital heart disease to predict ventricular tachyarrhythmias","volume":"119","author":"Vogels","year":"2017","journal-title":"Am J Cardiol"},{"key":"2026080913413607000_euac125-B91","doi-asserted-by":"crossref","first-page":"577","DOI":"10.23736\/S0026-4725.20.05123-3","article-title":"Fragmented QRS may be associated with complex ventricular arrhythmias in mitral valve prolapse","volume":"68","author":"Kaya","year":"2020","journal-title":"Minerva Cardioangiol"},{"key":"2026080913413607000_euac125-B92","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/j.hrcr.2020.07.009","article-title":"Short-coupled premature ventricular beats leading to ventricular fibrillation in a young patient: a sudden arrhythmia death syndrome case report and literature review","volume":"6","author":"von Alvensleben","year":"2020","journal-title":"HeartRhythm Case Rep"},{"key":"2026080913413607000_euac125-B93","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1016\/j.hrthm.2020.07.013","article-title":"Determining the optimal duration for premature ventricular contraction monitoring","volume":"17","author":"Hsia","year":"2020","journal-title":"Heart Rhythm"},{"key":"2026080913413607000_euac125-B94","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/j.1542-474X.2007.00150.x","article-title":"Prognostic significance of PVCs and resting heart rate","volume":"12","author":"Engel","year":"2007","journal-title":"Ann Noninvasive Electrocardiol"},{"key":"2026080913413607000_euac125-B95","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s10840-020-00775-1","article-title":"Long-term outcomes of ablation for ventricular arrhythmias in mitral valve prolapse","volume":"61","author":"Marano","year":"2021","journal-title":"J Interv Card Electrophysiol"},{"key":"2026080913413607000_euac125-B96","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/j.amjcard.2013.05.065","article-title":"Meta-analysis of ventricular premature complexes and their relation to cardiac mortality in general populations","volume":"112","author":"Ataklte","year":"2013","journal-title":"Am J Cardiol"},{"key":"2026080913413607000_euac125-B97","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jacc.2015.04.062","article-title":"Ventricular ectopy as a predictor of heart failure and death","volume":"66","author":"Dukes","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"2026080913413607000_euac125-B98","doi-asserted-by":"crossref","first-page":"990","DOI":"10.7326\/0003-4819-117-12-990","article-title":"Prognostic implications of asymptomatic ventricular arrhythmias: the Framingham Heart Study","volume":"117","author":"Bikkina","year":"1992","journal-title":"Ann Intern Med"},{"key":"2026080913413607000_euac125-B99","doi-asserted-by":"crossref","first-page":"e0160181","DOI":"10.1371\/journal.pone.0160181","article-title":"Long-term outcome of non-sustained ventricular tachycardia in structurally normal hearts","volume":"11","author":"Lin","year":"2016","journal-title":"PLoS One"},{"key":"2026080913413607000_euac125-B100","doi-asserted-by":"crossref","first-page":"2827","DOI":"10.1093\/eurheartj\/ehab275","article-title":"Short-coupled ventricular fibrillation represents a distinct phenotype among latent causes of unexplained cardiac arrest: a report from the CASPER registry","volume":"42","author":"Steinberg","year":"2021","journal-title":"Eur Heart J"},{"key":"2026080913413607000_euac125-B101","doi-asserted-by":"crossref","first-page":"2904","DOI":"10.1016\/j.jacc.2018.09.048","article-title":"Arrhythmic mitral valve prolapse: JACC review topic of the week","volume":"72","author":"Miller","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"2026080913413607000_euac125-B102","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1093\/eurheartj\/ehy037","article-title":"2018 ESC guidelines for the diagnosis and management of syncope","volume":"39","author":"Brignole","year":"2018","journal-title":"Eur Heart J"},{"key":"2026080913413607000_euac125-B103","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1093\/ehjci\/jet105","article-title":"Recommendations for the echocardiographic assessment of native valvular regurgitation: an executive summary from the European Association of Cardiovascular Imaging","volume":"14","author":"Lancellotti","year":"2013","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2026080913413607000_euac125-B104","doi-asserted-by":"crossref","first-page":"e171","DOI":"10.1093\/ehjci\/jeab253","article-title":"Multi-modality imaging assessment of native valvular regurgitation: an EACVI and ESC council of valvular heart disease position paper","volume":"23","author":"Lancellotti","year":"2022","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2026080913413607000_euac125-B105","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1016\/j.jacc.2009.06.047","article-title":"Survival implication of left ventricular end-systolic diameter in mitral regurgitation due to flail leaflets: a long-term follow-up multicenter study","volume":"54","author":"Tribouilloy","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"2026080913413607000_euac125-B106","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1161\/CIRCIMAGING.113.001251","article-title":"Long-term mortality associated with left ventricular dysfunction in mitral regurgitation due to flail leaflets: a multicenter analysis","volume":"7","author":"Tribouilloy","year":"2014","journal-title":"Circ Cardiovasc Imaging"},{"key":"2026080913413607000_euac125-B107","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1111\/jce.12914","article-title":"Bileaflet mitral valve prolapse and risk of ventricular dysrhythmias and death","volume":"27","author":"Nordhues","year":"2016","journal-title":"J Cardiovasc Electrophysiol"},{"key":"2026080913413607000_euac125-B108","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.amjcard.2007.10.029","article-title":"Risk, determinants, and outcome implications of progression of mitral regurgitation after diagnosis of mitral valve prolapse in a single community","volume":"101","author":"Avierinos","year":"2008","journal-title":"Am J Cardiol"},{"key":"2026080913413607000_euac125-B109","first-page":"323","article-title":"Interactions between mitral valve and left ventricle analysed by 2D speckle tracking in patients with mitral valve prolapse: one more piece to the puzzle","volume":"18","author":"Huttin","year":"2017","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2026080913413607000_euac125-B110","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.jacc.2018.06.048","article-title":"Myocardial fibrosis in patients with primary mitral regurgitation with and without prolapse","volume":"72","author":"Kitkungvan","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"2026080913413607000_euac125-B111","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.jcmg.2008.01.013","article-title":"Cardiovascular magnetic resonance characterization of mitral valve prolapse","volume":"1","author":"Han","year":"2008","journal-title":"JACC Cardiovasc Imaging"},{"key":"2026080913413607000_euac125-B112","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1136\/heartjnl-2016-309303","article-title":"Diffuse myocardial fibrosis in patients with mitral valve prolapse and ventricular arrhythmia","volume":"103","author":"Bui","year":"2017","journal-title":"Heart"},{"key":"2026080913413607000_euac125-B113","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1161\/CIRCULATIONAHA.120.050214","article-title":"Replacement myocardial fibrosis in patients with mitral valve prolapse: relation to mitral regurgitation, ventricular remodeling, and arrhythmia","volume":"143","author":"Constant Dit Beaufils","year":"2021","journal-title":"Circulation"},{"key":"2026080913413607000_euac125-B114","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1161\/01.CIR.39.5.611","article-title":"Possible X-linked congenital heart disease","volume":"39","author":"Monteleone","year":"1969","journal-title":"Circulation"},{"key":"2026080913413607000_euac125-B115","doi-asserted-by":"crossref","first-page":"826","DOI":"10.7326\/0003-4819-97-6-826","article-title":"Inheritance of mitral valve prolapse: effect of age and sex on gene expression","volume":"97","author":"Devereux","year":"1982","journal-title":"Ann Intern Med"},{"key":"2026080913413607000_euac125-B116","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/j.mayocp.2018.11.028","article-title":"A novel truncating variant in FLNC-encoded filamin C may serve as a proarrhythmic genetic substrate for arrhythmogenic bileaflet mitral valve prolapse syndrome","volume":"94","author":"Bains","year":"2019","journal-title":"Mayo Clin Proc"},{"key":"2026080913413607000_euac125-B117","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1038\/nature14670","article-title":"Mutations in DCHS1 cause mitral valve prolapse","volume":"525","author":"Durst","year":"2015","journal-title":"Nature"},{"key":"2026080913413607000_euac125-B118","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22042102","article-title":"Putative circulating MicroRNAs are able to identify patients with mitral valve prolapse and severe regurgitation","volume":"22","author":"Songia","year":"2021","journal-title":"Int J Mol Sci"},{"key":"2026080913413607000_euac125-B119","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.jprot.2013.10.009","article-title":"Proteomics discovery of biomarkers for mitral regurgitation caused by mitral valve prolapse","volume":"94","author":"Tan","year":"2013","journal-title":"J Proteomics"},{"key":"2026080913413607000_euac125-B120","doi-asserted-by":"crossref","first-page":"2934","DOI":"10.1002\/pmic.201500040","article-title":"Unravelling the proteome of degenerative human mitral valves","volume":"15","author":"Tan","year":"2015","journal-title":"Proteomics"},{"key":"2026080913413607000_euac125-B121","doi-asserted-by":"crossref","first-page":"e001016","DOI":"10.1136\/openhrt-2019-001016","article-title":"Increased levels of sST2 in patients with mitral annulus disjunction and ventricular arrhythmias","volume":"6","author":"Scheirlynck","year":"2019","journal-title":"Open Heart"},{"key":"2026080913413607000_euac125-B122","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1093\/cvr\/cvt083","article-title":"TGF-beta signalling and reactive oxygen species drive fibrosis and matrix remodelling in myxomatous mitral valves","volume":"99","author":"Hagler","year":"2013","journal-title":"Cardiovasc Res"},{"key":"2026080913413607000_euac125-B123","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.carpath.2015.07.009","article-title":"TGF-beta1 pathway activation and adherens junction molecular pattern in nonsyndromic mitral valve prolapse","volume":"24","author":"Rizzo","year":"2015","journal-title":"Cardiovasc Pathol"},{"key":"2026080913413607000_euac125-B124","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1007\/s00428-017-2221-0","article-title":"Guidelines for autopsy investigation of sudden cardiac death: 2017 update from the Association for European Cardiovascular Pathology","volume":"471","author":"Basso","year":"2017","journal-title":"Virchows Archiv Int J Pathol"},{"key":"2026080913413607000_euac125-B125","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1161\/01.CIR.67.3.632","article-title":"The myxomatous mitral valve and sudden death","volume":"67","author":"Chesler","year":"1983","journal-title":"Circulation"},{"key":"2026080913413607000_euac125-B126","doi-asserted-by":"crossref","first-page":"3179","DOI":"10.1111\/jce.15270","article-title":"Characterization of the electrophysiological substrate in patients with Barlow\u2019s disease","volume":"32","author":"Vergara","year":"2021","journal-title":"J Cardiovasc Electrophysiol"},{"key":"2026080913413607000_euac125-B127","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0008-6363(99)00390-9","article-title":"Mechano-electrical feedback","volume":"45","author":"Franz","year":"2000","journal-title":"Cardiovasc Res"},{"key":"2026080913413607000_euac125-B128","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1111\/jce.13900","article-title":"Papillary muscle ventricular arrhythmias in patients with arrhythmic mitral valve prolapse: electrophysiologic substrate and catheter ablation outcomes","volume":"30","author":"Enriquez","year":"2019","journal-title":"J Cardiovasc Electrophysiol"},{"key":"2026080913413607000_euac125-B129","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.116.004005","article-title":"Sites of successful ventricular fibrillation ablation in bileaflet mitral valve prolapse syndrome","volume":"9","author":"Syed","year":"2016","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2026080913413607000_euac125-B130","doi-asserted-by":"crossref","first-page":"2426","DOI":"10.1016\/j.hrthm.2015.08.020","article-title":"Contemporary rates of appropriate shock therapy in patients who receive implantable device therapy in a real-world setting: from the Israeli ICD registry","volume":"12","author":"Sabbag","year":"2015","journal-title":"Heart Rhythm"},{"key":"2026080913413607000_euac125-B131","doi-asserted-by":"crossref","first-page":"3781","DOI":"10.1093\/eurheartj\/ehaa645","article-title":"The PROFID project","volume":"41","author":"Dagres","year":"2020","journal-title":"Eur Heart J"},{"key":"2026080913413607000_euac125-B132","first-page":"1601","article-title":"2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: the task force for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death of the European Society of Cardiology (ESC) endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC)","volume":"17","author":"Priori","year":"2015","journal-title":"Europace"},{"key":"2026080913413607000_euac125-B133","doi-asserted-by":"crossref","DOI":"10.1093\/eurheartj\/ehab368","article-title":"2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure","author":"McDonagh","year":"2021","journal-title":"Eur Heart J"},{"key":"2026080913413607000_euac125-B134","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.hrthm.2004.12.014","article-title":"Using the twelve-lead electrocardiogram to localize the site of origin of ventricular tachycardia","volume":"2","author":"Josephson","year":"2005","journal-title":"Heart Rhythm"},{"key":"2026080913413607000_euac125-B135","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1016\/j.hrthm.2019.04.002","article-title":"How to use the 12-lead ECG to predict the site of origin of idiopathic ventricular arrhythmias","volume":"16","author":"Enriquez","year":"2019","journal-title":"Heart Rhythm"},{"key":"2026080913413607000_euac125-B136","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1161\/CIRCEP.115.002847","article-title":"Twelve-lead ECG of ventricular tachycardia in structural heart disease","volume":"8","author":"de Riva","year":"2015","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2026080913413607000_euac125-B137","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1161\/CIRCEP.114.002619","article-title":"Differentiation of papillary muscle from fascicular and mitral annular ventricular arrhythmias in patients with and without structural heart disease","volume":"8","author":"Al\u2019Aref","year":"2015","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2026080913413607000_euac125-B138","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1111\/j.1540-8167.2005.40749.x","article-title":"Idiopathic left ventricular tachycardia originating from the mitral annulus","volume":"16","author":"Kumagai","year":"2005","journal-title":"J Cardiovasc Electrophysiol"},{"key":"2026080913413607000_euac125-B139","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/j.jacc.2004.12.025","article-title":"Idiopathic ventricular arrhythmia arising from the mitral annulus: a distinct subgroup of idiopathic ventricular arrhythmias","volume":"45","author":"Tada","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"2026080913413607000_euac125-B140","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1378\/chest.59.6.643","article-title":"The syndrome associated with mid-systolic click and-or late systolic murmur. Analysis of 32 cases","volume":"59","author":"Jeresaty","year":"1971","journal-title":"Chest"},{"key":"2026080913413607000_euac125-B141","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/0002-8703(66)90179-7","article-title":"Aneurysmal protrusion of the posterior leaflet of the mitral valve. An auscultatory-electrocardiographic syndrome","volume":"71","author":"Barlow","year":"1966","journal-title":"Am Heart J"},{"key":"2026080913413607000_euac125-B142","doi-asserted-by":"crossref","first-page":"12698","DOI":"10.1038\/s41598-021-92088-0","article-title":"Premature ventricular contraction increases the risk of heart failure and ventricular tachyarrhythmia","volume":"11","author":"Kim","year":"2021","journal-title":"Sci Rep"},{"key":"2026080913413607000_euac125-B143","first-page":"289","article-title":"Mitral annular disjunction-a new disease spectrum","volume":"39","author":"Tani","year":"2021","journal-title":"Cardiol Clin"},{"key":"2026080913413607000_euac125-B144","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.jacep.2019.03.013","article-title":"Premature ventricular complex-induced cardiomyopathy","volume":"5","author":"Latchamsetty","year":"2019","journal-title":"JACC Clin Electrophysiol"},{"key":"2026080913413607000_euac125-B145","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1093\/europace\/euz046","article-title":"Management of asymptomatic arrhythmias: a European Heart Rhythm Association (EHRA) consensus document, endorsed by the Heart Failure Association (HFA), Heart Rhythm Society (HRS), Asia Pacific Heart Rhythm Society (APHRS), Cardiac Arrhythmia Society of Southern Africa (CASSA), and Latin America Heart Rhythm Society (LAHRS)","volume":"21","author":"Arnar","year":"2019","journal-title":"Europace"},{"key":"2026080913413607000_euac125-B146","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1002\/joa3.12142","article-title":"Implantable loop recorder in clinical practice","volume":"35","author":"Bisignani","year":"2019","journal-title":"J Arrhythm"},{"key":"2026080913413607000_euac125-B147","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1111\/pace.13533","article-title":"Diagnostic and therapeutic value of implantable loop recorder: a tertiary care center experience","volume":"42","author":"Padmanabhan","year":"2019","journal-title":"Pacing Clin Electrophysiol"},{"key":"2026080913413607000_euac125-B148","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.hrcr.2020.06.015","article-title":"Unrecognized ventricular tachycardia in a patient with mitral annulus disjunction and syncope","volume":"6","author":"Freeman","year":"2020","journal-title":"HeartRhythm Case Rep"},{"key":"2026080913413607000_euac125-B149","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2020-235322","article-title":"Malignant mitral valve prolapse: an uncommon variation of a common condition","volume":"13","author":"Joyce","year":"2020","journal-title":"BMJ Case Rep"},{"key":"2026080913413607000_euac125-B150","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1016\/j.echo.2005.10.005","article-title":"Recommendations for chamber quantification: a report from the American Society of Echocardiography\u2019s guidelines and standards committee and the chamber quantification writing group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology","volume":"18","author":"Lang","year":"2005","journal-title":"J Am Soc Echocardiogr"},{"key":"2026080913413607000_euac125-B151","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.1007\/s10554-020-01927-0","article-title":"Defining the left ventricular base in mitral valve prolapse: impact on systolic function and regurgitation","volume":"36","author":"Wolff","year":"2020","journal-title":"Int J Cardiovasc Imaging"},{"key":"2026080913413607000_euac125-B152","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1136\/hrt.40.5.468","article-title":"The floppy mitral valve: study of incidence, pathology and complications in surgical, necropsy and forensic material","volume":"40","author":"Davies","year":"1978","journal-title":"Br Heart J"},{"key":"2026080913413607000_euac125-B153","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1016\/j.jcmg.2016.09.016","article-title":"The pickelhaube sign: novel echocardiographic risk marker for malignant mitral valve prolapse syndrome","volume":"10","author":"Muthukumar","year":"2017","journal-title":"JACC Cardiovasc Imaging"},{"key":"2026080913413607000_euac125-B154","doi-asserted-by":"crossref","first-page":"2793","DOI":"10.1093\/eurheartj\/ehv316","article-title":"2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: the task force for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death of the European Society of Cardiology (ESC). Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC)","volume":"36","author":"Priori","year":"2015","journal-title":"Eur Heart J"},{"key":"2026080913413607000_euac125-B155","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1161\/CIRCIMAGING.111.966085","article-title":"Utility of cardiovascular magnetic resonance in identifying substrate for malignant ventricular arrhythmias","volume":"5","author":"White","year":"2012","journal-title":"Circ Cardiovasc Imaging"},{"key":"2026080913413607000_euac125-B156","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1007\/s00330-020-07140-w","article-title":"T1 mapping and cardiac magnetic resonance feature tracking in mitral valve prolapse","volume":"31","author":"Guglielmo","year":"2021","journal-title":"Eur Radiol"},{"key":"2026080913413607000_euac125-B157","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.hrthm.2020.10.010","article-title":"2020 APHRS\/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families","volume":"18","author":"Stiles","year":"2021","journal-title":"Heart Rhythm"},{"key":"2026080913413607000_euac125-B158","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1111\/j.1540-8159.1994.tb01466.x","article-title":"Ventricular arrhythmia factors in mitral valve prolapse","volume":"17","author":"Babuty","year":"1994","journal-title":"Pacing Clin Electrophysiol"},{"key":"2026080913413607000_euac125-B159","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/0002-9149(84)90697-0","article-title":"Programmed ventricular stimulation in mitral valve prolapse: analysis of 36 patients","volume":"53","author":"Morady","year":"1984","journal-title":"Am J Cardiol"},{"key":"2026080913413607000_euac125-B160","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1016\/0002-8703(85)90194-2","article-title":"The yield of programmed ventricular stimulation in mitral valve prolapse patients with ventricular arrhythmias","volume":"110","author":"Rosenthal","year":"1985","journal-title":"Am Heart J"},{"key":"2026080913413607000_euac125-B161","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1056\/NEJMoa022353","article-title":"Frequent ventricular ectopy after exercise as a predictor of death","volume":"348","author":"Frolkis","year":"2003","journal-title":"N Engl J Med"},{"key":"2026080913413607000_euac125-B162","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1016\/j.jacc.2021.09.1366","article-title":"Exercise-induced ventricular ectopy and cardiovascular mortality in asymptomatic individuals","volume":"78","author":"Refaat","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"2026080913413607000_euac125-B163","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/eurheartj\/ehaa605","article-title":"2020 ESC Guidelines on sports cardiology and exercise in patients with cardiovascular disease","volume":"42","author":"Pelliccia","year":"2021","journal-title":"Eur Heart J"},{"key":"2026080913413607000_euac125-B164","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/eurheartj\/ehz425","article-title":"2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes","volume":"41","author":"Knuuti","year":"2020","journal-title":"Eur Heart J"},{"key":"2026080913413607000_euac125-B165","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1161\/CIRCEP.113.000805","article-title":"Radiofrequency ablation versus antiarrhythmic medication for treatment of ventricular premature beats from the right ventricular outflow tract","volume":"7","author":"Ling","year":"2014","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2026080913413607000_euac125-B166","doi-asserted-by":"crossref","first-page":"e10","DOI":"10.1067\/mhj.2002.125516","article-title":"Effect of atenolol on symptomatic ventricular arrhythmia without structural heart disease: a randomized placebo-controlled study","volume":"144","author":"Krittayaphong","year":"2002","journal-title":"Am Heart J"},{"key":"2026080913413607000_euac125-B167","first-page":"351","article-title":"Benign symptomatic premature ventricular complexes: short- and long-term efficacy of antiarrhythmic drugs and radiofrequency ablation","volume":"70","author":"Stec","year":"2012","journal-title":"Kardiol Pol"},{"key":"2026080913413607000_euac125-B168","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1056\/NEJM199507133330201","article-title":"Amiodarone in patients with congestive heart failure and asymptomatic ventricular arrhythmia. Survival trial of antiarrhythmic therapy in congestive heart failure","volume":"333","author":"Singh","year":"1995","journal-title":"N Engl J Med"},{"key":"2026080913413607000_euac125-B169","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.hrthm.2017.12.018","article-title":"Class IC antiarrhythmic drugs for suspected premature ventricular contraction-induced cardiomyopathy","volume":"15","author":"Hyman","year":"2018","journal-title":"Heart Rhythm"},{"key":"2026080913413607000_euac125-B170","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/S0735-1097(86)80414-4","article-title":"Multicenter trial of sotalol for suppression of frequent, complex ventricular arrhythmias: a double-blind, randomized, placebo-controlled evaluation of two doses","volume":"8","author":"Anderson","year":"1986","journal-title":"J Am Coll Cardiol"},{"key":"2026080913413607000_euac125-B171","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s10840-015-0090-5","article-title":"Reduction in malignant ventricular arrhythmia and appropriate shocks following surgical correction of bileaflet mitral valve prolapse","volume":"46","author":"Vaidya","year":"2016","journal-title":"J Interv Card Electrophysiol"},{"key":"2026080913413607000_euac125-B172","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.hrcr.2017.11.002","article-title":"Recurrent premature ventricular contraction-induced ventricular fibrillation and resuscitated sudden death in a 26-year-old pregnant woman with bileaflet mitral valve prolapse","volume":"4","author":"Saha","year":"2018","journal-title":"HeartRhythm Case Rep"},{"key":"2026080913413607000_euac125-B173","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1016\/j.ijcard.2016.06.252","article-title":"Ventricular premature contraction associated with mitral valve prolapse","volume":"221","author":"Hong","year":"2016","journal-title":"Int J Cardiol"},{"key":"2026080913413607000_euac125-B174","doi-asserted-by":"crossref","first-page":"2304","DOI":"10.1161\/CIRCULATIONAHA.118.038036","article-title":"Quinidine-responsive polymorphic ventricular tachycardia in patients with coronary heart disease","volume":"139","author":"Viskin","year":"2019","journal-title":"Circulation"},{"key":"2026080913413607000_euac125-B175","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1111\/pace.13613","article-title":"Management and outcomes in mitral valve prolapse with ventricular arrhythmias undergoing ablation and\/or implantation of ICDs","volume":"42","author":"Bumgarner","year":"2019","journal-title":"Pacing Clin Electrophysiol"},{"key":"2026080913413607000_euac125-B176","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1111\/jce.13338","article-title":"The tip of the muscle is a dominant location of ventricular ectopy originating from papillary muscles in the left ventricle","volume":"29","author":"Peichl","year":"2018","journal-title":"J Cardiovasc Electrophysiol"},{"key":"2026080913413607000_euac125-B177","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1002\/joa3.12137","article-title":"Updated results on catheter ablation of ventricular arrhythmias arising from the papillary muscles of the left ventricle","volume":"35","author":"Rivera","year":"2019","journal-title":"J Arrhythm"},{"key":"2026080913413607000_euac125-B178","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1111\/pace.13363","article-title":"Catheter ablation of papillary muscle arrhythmias: Implications of mitral valve prolapse and systolic dysfunction","volume":"41","author":"Lee","year":"2018","journal-title":"Pacing Clin Electrophysiol"},{"key":"2026080913413607000_euac125-B179","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1093\/europace\/euz132","article-title":"2019 HRS\/EHRA\/APHRS\/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias","volume":"21","author":"Cronin","year":"2019","journal-title":"Europace"},{"key":"2026080913413607000_euac125-B180","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.hrcr.2017.01.003","article-title":"Worsening of mitral valve regurgitation after radiofrequency catheter ablation of ventricular arrhythmia originating from a left ventricular papillary muscle","volume":"3","author":"Mochizuki","year":"2017","journal-title":"HeartRhythm Case Rep"},{"key":"2026080913413607000_euac125-B181","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0002-8703(91)90976-O","article-title":"Mitral valvuloplasty for life-threatening ventricular arrhythmias in mitral valve prolapse","volume":"121","author":"Pocock","year":"1991","journal-title":"Am Heart J"},{"key":"2026080913413607000_euac125-B182","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0022-5223(19)38136-X","article-title":"Surgical correction of severe mitral prolapse without mitral insufficiency but with pronounced cardiac arrhythmias","volume":"78","author":"Kay","year":"1979","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2026080913413607000_euac125-B183","first-page":"397","article-title":"Arrhythmia with mitral valve prolapse: results of annuloplasty in two patients","volume":"5","author":"Al-Bassam","year":"1978","journal-title":"Cardiovasc Dis"},{"key":"2026080913413607000_euac125-B184","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S0022-0736(78)80131-9","article-title":"Refractory ventricular arrhythmias in a patient with mitral valve prolapse. Successful control with mitral valve replacement","volume":"11","author":"Ross","year":"1978","journal-title":"J Electrocardiol"},{"key":"2026080913413607000_euac125-B185","first-page":"391","article-title":"Mitral valve replacement in a patient with mitral valve prolapse complicated by severe ventricular arrhythmias","volume":"35","author":"Missotten","year":"1980","journal-title":"Acta Cardiol"},{"key":"2026080913413607000_euac125-B186","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1007\/s00246-006-1102-0","article-title":"Surgical correction of mitral valve prolapse: a cure for recurrent ventricular tachycardia in Marfan syndrome?","volume":"27","author":"Beroukhim","year":"2006","journal-title":"Pediatr Cardiol"},{"key":"2026080913413607000_euac125-B187","doi-asserted-by":"crossref","first-page":"e16","DOI":"10.1016\/j.ijcard.2014.07.174","article-title":"Mitral valve repair is an effective treatment for ventricular arrhythmias in mitral valve prolapse syndrome","volume":"177","author":"Abbadi","year":"2014","journal-title":"Int J Cardiol"},{"key":"2026080913413607000_euac125-B188","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.hrcr.2018.02.012","article-title":"Mitral valve repair results in suppression of ventricular arrhythmias and normalization of repolarization abnormalities in mitral valve prolapse","volume":"4","author":"Alqarawi","year":"2018","journal-title":"HeartRhythm Case Rep"},{"key":"2026080913413607000_euac125-B189","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.ipej.2016.10.009","article-title":"The effect of mitral valve surgery on ventricular arrhythmia in patients with bileaflet mitral valve prolapse","volume":"16","author":"Naksuk","year":"2016","journal-title":"Indian Pacing Electrophysiol J"},{"key":"2026080913413607000_euac125-B190","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1111\/j.1540-8159.1993.tb01599.x","article-title":"Malignant ventricular arrhythmias in patients with mitral valve prolapse and mild mitral regurgitation","volume":"16","author":"Vohra","year":"1993","journal-title":"PACE"},{"key":"2026080913413607000_euac125-B191","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1046\/j.1460-9592.2001.01029.x","article-title":"Successful surgical ablation of sustained ventricular tachycardia associated with mitral valve prolapse guided by a multielectrode basket catheter","volume":"24","author":"Van Dessel","year":"2001","journal-title":"Pacing Clin Electrophysiol"},{"key":"2026080913413607000_euac125-B192","doi-asserted-by":"crossref","first-page":"3061","DOI":"10.1016\/j.jacc.2020.10.037","article-title":"Surgical cryoablation of papillary muscle PVCs during mitral valve surgery: therapeutic consideration for malignant MVP","volume":"76","author":"El-Eshmawi","year":"2020","journal-title":"J Am Coll Cardiol"}],"container-title":["Europace"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/europace\/article-pdf\/24\/12\/1981\/60919389\/euac125.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/europace\/article-pdf\/24\/12\/1981\/60919389\/euac125.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T17:42:03Z","timestamp":1786297323000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/europace\/article\/24\/12\/1981\/6661340"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,11]]},"references-count":192,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12,9]]}},"URL":"https:\/\/doi.org\/10.1093\/europace\/euac125","relation":{},"ISSN":["1099-5129","1532-2092"],"issn-type":[{"value":"1099-5129","type":"print"},{"value":"1532-2092","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,12,1]]},"published":{"date-parts":[[2022,8,11]]}}}