{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T03:27:40Z","timestamp":1793935660762,"version":"4.8.0"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2022,11,11]],"date-time":"2022-11-11T00:00:00Z","timestamp":1668124800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Left bundle branch area pacing (LBBAP) has been shown to be effective and safe. Limited data are available on LBBAP in the congenital heart disease (CHD) population. This study aims to describe the feasibility and safety of LBBAP in CHD patients compared with non-CHD patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>This is a single-centre, non-randomized observational study recruiting consecutive patients with bradycardia indication. Demographic data, ECGs, imaging, and procedural data including lead parameters were recorded. A total of 39 patients were included: CHD group (n = 13) and non-CHD group (n = 26). Congenital heart disease patients were younger (55 \u00b1 14.5 years vs. 73.2 \u00b1 13.1, P &amp;lt; 0.001). Acute success was achieved in all CHD patients and 96% (25\/26) of non-CHD patients. No complications were encountered in either group. The procedural time for CHD patients was comparable (96.4 \u00b1 54 vs. 82.1 \u00b1 37.9 min, P = 0.356). Sheath reshaping was required in 7 of 13 CHD patients but only in 1 of 26 non-CHD patients, reflecting the complex and distorted anatomy of the patients in this group. Lead parameters were similar in both groups; R wave (11 \u00b1 7 mV vs. 11.5 \u00b1 7.5, P = 0.881) and pacing threshold (0.6 \u00b1 0.3 V vs. 0.7 \u00b1 0.3, P = 0.392). Baseline QRS duration was longer in the CHD group (150 \u00b1 28.2 vs. 118.6 \u00b1 26.6 ms, P = 0.002). Despite a numerically greater reduction in QRS and a similar left ventricular activation time (65.9 \u00b1 6.2 vs. 67 \u00b1 16.8 ms, P = 0.840), the QRS remained longer in the CHD group (135.5 \u00b1 22.4 vs. 106.9 \u00b1 24.7 ms, P = 0.005).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Left bundle branch area pacing is feasible and safe in CHD patients as compared to that in non-CHD patients. Procedural and fluoroscopy times did not differ between both groups. Lead parameters were satisfactory and stable over a short-term follow-up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/europace\/euac175","type":"journal-article","created":{"date-parts":[[2022,11,6]],"date-time":"2022-11-06T16:42:15Z","timestamp":1667752935000},"page":"561-570","source":"Crossref","is-referenced-by-count":29,"title":["Left bundle branch area pacing in congenital heart disease"],"prefix":"10.1093","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4659-2529","authenticated-orcid":false,"given":"Matthew","family":"O\u2019Connor","sequence":"first","affiliation":[{"name":"Heart Rhythm Centre, Royal Brompton and Harefield Hospitals, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust , London SW3 6NP , UK"},{"name":"Adult Congenital Heart Centre, Royal Brompton and Harefield Hospitals, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust , Sydney Street, London SW3 6NP , UK"},{"name":"Department of Electrophysiology, Auckland City Hospital , Auckland 1023 , New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2008-1373","authenticated-orcid":false,"given":"Omar","family":"Riad","sequence":"additional","affiliation":[{"name":"Heart Rhythm Centre, Royal Brompton and Harefield Hospitals, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust , London SW3 6NP , UK"},{"name":"Cardiology Department, Ain Shams University , Cairo 1181 , Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Shi","sequence":"additional","affiliation":[{"name":"Heart Rhythm Centre, Royal Brompton and Harefield Hospitals, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust , London SW3 6NP , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6304-4014","authenticated-orcid":false,"given":"Dan","family":"Hunnybun","sequence":"additional","affiliation":[{"name":"Heart Rhythm Centre, Royal Brompton and Harefield Hospitals, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust , London SW3 6NP , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3394-5559","authenticated-orcid":false,"given":"Wei","family":"Li","sequence":"additional","affiliation":[{"name":"Heart Rhythm Centre, Royal Brompton and Harefield Hospitals, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust , London SW3 6NP , UK"},{"name":"Adult Congenital Heart Centre, Royal Brompton and Harefield Hospitals, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust , Sydney Street, London SW3 6NP , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian W E","family":"Jarman","sequence":"additional","affiliation":[{"name":"Heart Rhythm Centre, Royal Brompton and Harefield Hospitals, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust , London SW3 6NP , UK"},{"name":"Adult Congenital Heart Centre, Royal Brompton and Harefield Hospitals, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust , Sydney Street, London SW3 6NP , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6608-4230","authenticated-orcid":false,"given":"John","family":"Foran","sequence":"additional","affiliation":[{"name":"Heart Rhythm Centre, Royal Brompton and Harefield Hospitals, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust , London SW3 6NP , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3930-1957","authenticated-orcid":false,"given":"Christopher A","family":"Rinaldi","sequence":"additional","affiliation":[{"name":"Kings College Hospital , London WC2R 2LS , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9385-1298","authenticated-orcid":false,"given":"Vias","family":"Markides","sequence":"additional","affiliation":[{"name":"Heart Rhythm Centre, Royal Brompton and Harefield Hospitals, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust , London SW3 6NP , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2700-7232","authenticated-orcid":false,"given":"Michael A","family":"Gatzoulis","sequence":"additional","affiliation":[{"name":"Adult Congenital Heart Centre, Royal Brompton and Harefield Hospitals, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust , Sydney Street, London SW3 6NP , UK"},{"name":"National Heart & Lung Institute, Imperial College , London SW3 6LY , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6484-4961","authenticated-orcid":false,"given":"Tom","family":"Wong","sequence":"additional","affiliation":[{"name":"Heart Rhythm Centre, Royal Brompton and Harefield Hospitals, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust , London SW3 6NP , UK"},{"name":"Adult Congenital Heart Centre, Royal Brompton and Harefield Hospitals, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust , Sydney Street, London SW3 6NP , UK"},{"name":"Kings College Hospital , London WC2R 2LS , UK"},{"name":"National Heart & Lung Institute, Imperial College , London SW3 6LY , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,11,11]]},"reference":[{"key":"2023021623570556600_","doi-asserted-by":"crossref","first-page":"e102","DOI":"10.1016\/j.hrthm.2014.05.009","article-title":"PACES\/HRS expert consensus statement on the recognition and management of arrhythmias in adult congenital heart disease","volume":"11","author":"Khairy","year":"2014","journal-title":"Heart Rhythm"},{"key":"2023021623570556600_","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1093\/eurheartj\/eht358","article-title":"Geriatric congenital heart disease: a new challenge in the care of adults with congenital heart disease?","volume":"35","author":"Baumgartner","year":"2014","journal-title":"Eur Heart 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