{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T22:08:41Z","timestamp":1791410921343,"version":"4.3.3"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2022,11,9]],"date-time":"2022-11-09T00:00:00Z","timestamp":1667952000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The safety and feasibility of combining percutaneous catheter ablation (CA) for atrial fibrillation with left atrial appendage occlusion (LAAO) as a single procedure in the USA have not been investigated. We analyzed the US National Readmission Database (NRD) to investigate the incidence of combined LAAO + CA and compare major adverse cardiovascular events (MACEs) with matched LAAO-only and CA-only patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>In this retrospective study from NRD data, we identified patients undergoing combined LAAO and CA procedures on the same day in the USA from 2016 to 2019. A 1:1 propensity score match was performed to identify patients undergoing LAAO-only and CA-only procedures. The number of LAAO + CA procedures increased from 28 (2016) to 119 (2019). LAAO + CA patients (n = 375, mean age 74 \u00b1 9.2 years, 53.4% were males) had non-significant higher MACE (8.1%) when compared with LAAO-only (n = 407, 5.3%) or CA-only patients (n = 406, 7.4%), which was primarily driven by higher rate of pericardial effusion (4.3%). All-cause 30-day readmission rates among LAAO + CA patients (10.7%) were similar when compared with LAAO-only (12.7%) or CA-only (17.5%) patients. The most frequent primary reason for readmissions among LAAO + CA and LAAO-only cohorts was heart failure (24.6 and 31.5%, respectively), while among the CA-only cohort, it was paroxysmal atrial fibrillation (25.7%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We report an 63% annual growth (from 28 procedures) in combined LAAO and CA procedures in the USA. There were no significant difference in MACE and all-cause 30-day readmission rates among LAAO + CA patients compared with matched LAAO-only or CA-only patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/europace\/euac181","type":"journal-article","created":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T08:09:08Z","timestamp":1664611748000},"page":"390-399","source":"Crossref","is-referenced-by-count":28,"title":["Combined atrial fibrillation ablation and left atrial appendage occlusion procedure in the United States: a propensity score matched analysis from 2016\u20132019 national readmission database"],"prefix":"10.1093","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7780-1047","authenticated-orcid":false,"given":"Deepak Kumar","family":"Pasupula","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Disease, Department of Internal Medicine, MercyOne North Iowa Medical Center , 1000 4th St SW, Mason City, IA 50401 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2850-5794","authenticated-orcid":false,"given":"Sudeep K","family":"Siddappa Malleshappa","sequence":"additional","affiliation":[{"name":"Division of Haematology-Oncology, Department of Internal Medicine, UMass Chan-Baystate , 759 Chestnut St, Springfield, MA 01199 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9804-898X","authenticated-orcid":false,"given":"Muhammad B","family":"Munir","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine, University of California Davis , 4150 V Street, Suite 3100, Sacramento, CA 95817 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6967-0171","authenticated-orcid":false,"given":"Anusha Ganapati","family":"Bhat","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Department of Internal Medicine, University of Maryland , 620 W Lexington St, Baltimore, MD 21201 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6806-4308","authenticated-orcid":false,"given":"Antony","family":"Anandaraj","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Disease, Department of Internal Medicine, MercyOne North Iowa Medical Center , 1000 4th St SW, Mason City, IA 50401 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7988-9636","authenticated-orcid":false,"given":"Avaneesh","family":"Jakkoju","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardiovascular Institute of South , 441 Heymann Blvd, Lafayette, LA 70503 , 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