{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:19:36Z","timestamp":1787008776716,"version":"build-2736575974"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T00:00:00Z","timestamp":1670457600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Left bundle branch area pacing (LBBAP) is a recent technique aiming at preservation of physiological ventricular electrical activation. Our goal was to assess mechanical synchrony parameters in relation to electrocardiographic features during LBBAP performed in routine practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>From June 2020 to August 2021, all patients of our institution with permanent pacemaker implantation indication were eligible for LBBAP. A \u2018qR\u2019 pattern in V1 and a delay from pacing spike to the peak of the R-wave in V6 &amp;lt; 80 ms defined a successful LBBAP. Electrocardiogram and echocardiography were performed during spontaneous rhythm and LBBAP: left ventricular mechanical synchrony (LVMS) parameters using 2D Speckle tracking and interventricular mechanical delay (IVMD) were collected. LBBAP was attempted with success in 134\/163 patients (82.2%). During LBBAP, the mean QRS width was 104 \u00b1 12 ms. In patients with left bundle branch block (n = 47), LBBAP provided a significant decrease of QRS width from 139 \u00b1 16 to 105 \u00b1 12 ms (P &amp;lt; 0.001) with reduction of LVMS (53 \u00b1 21 vs. 90 \u00b1 46 ms, P = 0.009), and IVMD (14 \u00b1 13 vs. 49 \u00b1 18 ms, P &amp;lt; 0.001). In patients with right bundle branch block (n = 38), LBBAP led to a significant decrease of QRS width from 134 \u00b1 14 to 106 \u00b1 13 ms (P &amp;lt; 0.001) with no effect on LVMS and a reduction of IVMD (17 \u00b1 14 vs. 50 \u00b1 16 ms, P &amp;lt; 0.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>LBBAP in routine practice preserved intra-ventricular mechanical synchrony in patients with narrow and RBBB QRS and improved asynchrony parameters in patients with LBBB.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/europace\/euac223","type":"journal-article","created":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T18:17:36Z","timestamp":1668622656000},"page":"526-535","source":"Crossref","is-referenced-by-count":28,"title":["Left bundle branch area pacing in patients with baseline narrow, left, or right bundle branch block QRS patterns: insights into electrocardiographic and echocardiographic features"],"prefix":"10.1093","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3979-0594","authenticated-orcid":false,"given":"Adrian","family":"Mirolo","sequence":"first","affiliation":[{"name":"Department of cardiology, Rouen University Hospital, CHU\u2014H\u00f4pitaux de Rouen , 1 rue de Germont, 76031 Rouen , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7188-2686","authenticated-orcid":false,"given":"Corentin","family":"Chaumont","sequence":"additional","affiliation":[{"name":"Department of cardiology, Rouen University Hospital, CHU\u2014H\u00f4pitaux de Rouen , 1 rue de Germont, 76031 Rouen , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathanael","family":"Auquier","sequence":"additional","affiliation":[{"name":"Department of cardiology, Jacques Monod Hospital , 29 Av. Pierre Mend\u00e8s France, 76290 Montivilliers , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaud","family":"Savoure","sequence":"additional","affiliation":[{"name":"Department of cardiology, Rouen University Hospital, CHU\u2014H\u00f4pitaux de Rouen , 1 rue de Germont, 76031 Rouen , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedicte","family":"Godin","sequence":"additional","affiliation":[{"name":"Department of cardiology, Rouen University Hospital, CHU\u2014H\u00f4pitaux de Rouen , 1 rue de Germont, 76031 Rouen , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4126-5203","authenticated-orcid":false,"given":"Florence","family":"Vandevelde","sequence":"additional","affiliation":[{"name":"Department of cardiology, Jacques Monod Hospital , 29 Av. 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