{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T09:02:17Z","timestamp":1790931737551,"version":"4.1.0"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2023,2,4]],"date-time":"2023-02-04T00:00:00Z","timestamp":1675468800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,30]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>The multielectrode radiofrequency balloon catheter (RFB) has been developed to achieve safe and effective pulmonary vein isolation (PVI) for atrial fibrillation (AF) ablation. This single-centre study aimed to evaluate the midterm clinical outcome and predictors of single-shot PVI with the novel RFB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>All consecutive patients with symptomatic paroxysmal or persistent AF undergoing first-time PVI with the RFB were prospectively included. Clinical and procedural parameters were systematically collected. The primary safety endpoint was defined as any major periprocedural complications. The primary efficacy endpoint consisted of freedom from any atrial tachyarrhythmias (ATas) lasting &amp;gt;30 s during the follow-up after a 3-month blanking period. Persistent single-shot PVI was defined as PVI achieved with a single RFB application without acute reconnection. A total of 104 consecutive patients (mean age 64.3 \u00b1 11.4 years, 56.7% males) were included. 15 patients (14.4%) presented with persistent AF. The procedure time was 59.0 min with a dwell time of 20.0 min. One major complication occurred in one patient. At a mean follow-up of 10.1 \u00b1 5.3 months, freedom from ATas was 82.9%. ATas occurred in 14 patients, 11\/69 patients (15.9%) with paroxysmal AF and 3\/13 (23.1%) with persistent AF. The best cut-offs to predict persistent single-shot PVI were impedance drop &amp;gt;19.2 \u2126 [area under the receiver operator characteristic curve (AUC) 0.74] and temperature rise &amp;gt;11.1\u00b0 C (AUC 0.77).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In a large cohort of patients undergoing PVI with the RFB, the complication rate was 1%. At a mid-term follow-up of 10.1 \u00b1 5.3 months, freedom from ATas was 82.9%. Specific cut-offs of impedance drop and temperature rise may be useful to predict persistent single-shot isolation.<\/jats:p><\/jats:sec>","DOI":"10.1093\/europace\/euad017","type":"journal-article","created":{"date-parts":[[2023,2,4]],"date-time":"2023-02-04T12:10:27Z","timestamp":1675512627000},"page":"896-904","source":"Crossref","is-referenced-by-count":29,"title":["Pulmonary vein isolation with the radiofrequency balloon catheter: a single centre prospective study"],"prefix":"10.1093","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6672-4931","authenticated-orcid":false,"given":"Alvise","family":"Del Monte","sequence":"first","affiliation":[{"name":"Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel\u2014Vrije Universiteit Brussel, European Reference Networks Guard-Heart , Laarbeeklaan 101, 1090, Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9743-1661","authenticated-orcid":false,"given":"Alexandre","family":"Almorad","sequence":"additional","affiliation":[{"name":"Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel\u2014Vrije Universiteit Brussel, European Reference Networks Guard-Heart , Laarbeeklaan 101, 1090, Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9769-1511","authenticated-orcid":false,"given":"Luigi","family":"Pannone","sequence":"additional","affiliation":[{"name":"Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel\u2014Vrije Universiteit Brussel, European Reference Networks Guard-Heart , Laarbeeklaan 101, 1090, Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3837-3462","authenticated-orcid":false,"given":"Domenico Giovanni","family":"Della Rocca","sequence":"additional","affiliation":[{"name":"Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel\u2014Vrije Universiteit Brussel, European Reference Networks Guard-Heart , Laarbeeklaan 101, 1090, Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3938-4948","authenticated-orcid":false,"given":"Antonio","family":"Bisignani","sequence":"additional","affiliation":[{"name":"Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel\u2014Vrije Universiteit Brussel, European Reference Networks Guard-Heart , Laarbeeklaan 101, 1090, Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5373-1689","authenticated-orcid":false,"given":"Cinzia","family":"Monaco","sequence":"additional","affiliation":[{"name":"Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel\u2014Vrije Universiteit Brussel, European Reference Networks Guard-Heart , Laarbeeklaan 101, 1090, Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1912-8330","authenticated-orcid":false,"given":"Sahar","family":"Mouram","sequence":"additional","affiliation":[{"name":"Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel\u2014Vrije Universiteit Brussel, European Reference Networks Guard-Heart , Laarbeeklaan 101, 1090, Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3157-9281","authenticated-orcid":false,"given":"Robbert","family":"Ramak","sequence":"additional","affiliation":[{"name":"Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel\u2014Vrije Universiteit Brussel, European Reference Networks Guard-Heart , Laarbeeklaan 101, 1090, Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4912-8753","authenticated-orcid":false,"given":"Ana\u00efs","family":"Gauthey","sequence":"additional","affiliation":[{"name":"Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel\u2014Vrije Universiteit Brussel, European Reference Networks Guard-Heart , Laarbeeklaan 101, 1090, Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0988-2698","authenticated-orcid":false,"given":"Ingrid","family":"Overeinder","sequence":"additional","affiliation":[{"name":"Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel\u2014Vrije Universiteit Brussel, European Reference Networks Guard-Heart , Laarbeeklaan 101, 1090, Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gezim","family":"Bala","sequence":"additional","affiliation":[{"name":"Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel\u2014Vrije Universiteit Brussel, European Reference Networks Guard-Heart , Laarbeeklaan 101, 1090, Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0078-9393","authenticated-orcid":false,"given":"Antonio","family":"Sorgente","sequence":"additional","affiliation":[{"name":"Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel\u2014Vrije Universiteit Brussel, European Reference Networks Guard-Heart , Laarbeeklaan 101, 1090, Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9094-2576","authenticated-orcid":false,"given":"Erwin","family":"Str\u00f6ker","sequence":"additional","affiliation":[{"name":"Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel\u2014Vrije Universiteit Brussel, European Reference Networks Guard-Heart , Laarbeeklaan 101, 1090, Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Sieira","sequence":"additional","affiliation":[{"name":"Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel\u2014Vrije Universiteit Brussel, European Reference Networks Guard-Heart , Laarbeeklaan 101, 1090, Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3172-6106","authenticated-orcid":false,"given":"Pedro","family":"Brugada","sequence":"additional","affiliation":[{"name":"Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel\u2014Vrije Universiteit Brussel, European Reference Networks Guard-Heart , Laarbeeklaan 101, 1090, Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6261-5110","authenticated-orcid":false,"given":"Mark","family":"La Meir","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Department, Universitair Ziekenhuis Brussel\u2014Vrije Universiteit Brussel , Laarbeeklaan 101, 1090, Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2967-1345","authenticated-orcid":false,"given":"Gian-Battista","family":"Chierchia","sequence":"additional","affiliation":[{"name":"Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel\u2014Vrije Universiteit Brussel, European Reference Networks Guard-Heart , Laarbeeklaan 101, 1090, Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9351-0760","authenticated-orcid":false,"given":"Carlo","family":"de Asmundis","sequence":"additional","affiliation":[{"name":"Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel\u2014Vrije Universiteit Brussel, European Reference Networks Guard-Heart , Laarbeeklaan 101, 1090, Brussels , Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,2,4]]},"reference":[{"key":"2023033021231575300_","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.119.007541","article-title":"Pulmonary vein isolation with a novel multielectrode radiofrequency balloon catheter that allows directionally tailored energy delivery: short-term outcomes from a multicenter first-in-human study (RADIANCE)","volume":"12","author":"Reddy","year":"2019","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1111\/jce.14476","article-title":"Use of a multi-electrode radiofrequency balloon catheter to achieve pulmonary vein isolation in patients with paroxysmal atrial fibrillation: 12-month outcomes of the RADIANCE study","volume":"31","author":"Dhillon","year":"2020","journal-title":"J Cardiovasc Electrophysiol"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1093\/europace\/euaa382","article-title":"Safety, effectiveness, and quality of life following pulmonary vein isolation with a multi-electrode radiofrequency balloon catheter in paroxysmal atrial fibrillation: 1-year outcomes from SHINE","volume":"23","author":"Schilling","year":"2021","journal-title":"Europace"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1007\/s10840-021-01094-9","article-title":"The optimized clinical workflow for pulmonary vein isolation with the radiofrequency balloon","volume":"64","author":"Almorad","year":"2022","journal-title":"J Interv Card Electrophysiol"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1093\/eurheartj\/ehaa612","article-title":"2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): the task force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC","volume":"42","author":"Hindricks","year":"2021","journal-title":"Eur Heart J"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"2374","DOI":"10.1177\/0962280216680383","article-title":"The choice of methods in determining the optimal cut-off value for quantitative diagnostic test evaluation","volume":"27","author":"Hajian-Tilaki","year":"2018","journal-title":"Stat Methods Med Res"},{"key":"2023033021231575300_"},{"key":"2023033021231575300_","author":"Kassambara"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.hrcr.2022.05.026","article-title":"Perforation of multipolar electroanatomic mapping catheter in the left atrial appendage during left atrial mapping","volume":"8","author":"Guan","year":"2022","journal-title":"HeartRhythm Case Rep"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.120.009112","article-title":"Prospective randomized evaluation of high power during CLOSE-guided pulmonary vein isolation: the POWER-AF study","volume":"14","author":"Wielandts","year":"2021","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1016\/j.hrthm.2013.08.012","article-title":"Clinical outcomes after repair of left atrial esophageal fistulas occurring after atrial fibrillation ablation procedures","volume":"10","author":"Singh","year":"2013","journal-title":"Heart Rhythm"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.hrthm.2014.10.033","article-title":"Reduced incidence of esophageal lesions by luminal esophageal temperature-guided second-generation cryoballoon ablation","volume":"12","author":"F\u00fcrnkranz","year":"2015","journal-title":"Heart Rhythm"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.hrthm.2018.09.027","article-title":"Temporal relationships between esophageal injury type and progression in patients undergoing atrial fibrillation catheter ablation","volume":"16","author":"Yarlagadda","year":"2019","journal-title":"Heart Rhythm"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"e275","DOI":"10.1016\/j.hrthm.2017.05.012","article-title":"2017 HRS\/EHRA\/ECAS\/APHRS\/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation","volume":"14","author":"Calkins","year":"2017","journal-title":"Heart Rhythm"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1093\/eurheartj\/ehw260","article-title":"Catheter ablation in patients with persistent atrial fibrillation","volume":"38","author":"Kirchhof","year":"2017","journal-title":"Eur Heart J"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.hrthm.2014.09.063","article-title":"Pulmonary vein isolation as index procedure for persistent atrial fibrillation: one-year clinical outcome after ablation using the second-generation cryoballoon","volume":"12","author":"Ciconte","year":"2015","journal-title":"Heart Rhythm"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1056\/NEJMoa1602014","article-title":"FIRE AND ICE investigators. Cryoballoon or radiofrequency ablation for paroxysmal atrial fibrillation","volume":"374","author":"Kuck","year":"2016","journal-title":"N Engl J Med"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.jacep.2021.02.014","article-title":"Pulsed field ablation of paroxysmal atrial fibrillation: 1-year outcomes of IMPULSE, PEFCAT, and PEFCAT II","volume":"7","author":"Reddy","year":"2021","journal-title":"JACC Clin Electrophysiol"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1093\/europace\/euaa157","article-title":"Standardized pulmonary vein isolation workflow to enclose veins with contiguous lesions: the multicentre VISTAX trial","volume":"22","author":"Duytschaever","year":"2020","journal-title":"Europace"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1093\/europace\/euab168","article-title":"Efficacy and safety of the GOLD FORCE multicentre randomized clinical trial: multielectrode phased radiofrequency vs. irrigated radiofrequency single-tip catheter with contact force ablation for treatment of symptomatic paroxysmal atrial fibrillation","volume":"23","author":"Wintgens","year":"2021","journal-title":"Europace"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.jacep.2020.11.009","article-title":"A novel temperature-controlled radiofrequency catheter ablation system used to treat patients with paroxysmal atrial fibrillation","volume":"7","author":"Kautzner","year":"2021","journal-title":"JACC Clin Electrophysiol"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s10840-021-00968-2","article-title":"Single procedural outcomes in the setting of percutaneous ablation for persistent atrial fibrillation: a propensity-matched score comparison between different strategies","volume":"64","author":"Bisignani","year":"2022","journal-title":"J Interv Card Electrophysiol"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"ii8","DOI":"10.1093\/europace\/euab268","article-title":"What we have learned: is pulmonary vein isolation still the cornerstone of atrial fibrillation ablation?","volume":"24","author":"Metzner","year":"2022","journal-title":"Europace"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"ii44","DOI":"10.1093\/europace\/euab258","article-title":"New energy sources and technologies for atrial fibrillation catheter ablation","volume":"24","author":"Boersma","year":"2022","journal-title":"Europace"},{"key":"2023033021231575300_","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1111\/jce.13698","article-title":"Laser balloon ablation for AF: A systematic review and meta-analysis","volume":"29","author":"Reynolds","year":"2018","journal-title":"J Cardiovasc Electrophysiol"}],"container-title":["EP Europace"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/europace\/article-pdf\/25\/3\/896\/49704124\/euad017.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/europace\/article-pdf\/25\/3\/896\/49704124\/euad017.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T04:38:58Z","timestamp":1701751138000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/europace\/article\/25\/3\/896\/7026075"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,4]]},"references-count":25,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023,2,4]]},"published-print":{"date-parts":[[2023,3,30]]}},"URL":"https:\/\/doi.org\/10.1093\/europace\/euad017","relation":{},"ISSN":["1099-5129","1532-2092"],"issn-type":[{"value":"1099-5129","type":"print"},{"value":"1532-2092","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,3,1]]},"published":{"date-parts":[[2023,2,4]]}}}