{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T09:27:16Z","timestamp":1769851636247,"version":"3.49.0"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T00:00:00Z","timestamp":1676505600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Leipzig Heart Institute"},{"DOI":"10.13039\/501100008678","name":"Leipzig University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100008678","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>Coherent mapping (CM) uses a new algorithm to identify critical conduction isthmuses of atrial tachycardias (ATs). We analysed our experience of ablation of AT in patients with congenital heart disease (CHD) with this new technology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and results<\/jats:title><jats:p>All patients with CHD who had CM of AT using the high-density mapping PENTARAY\u2122 catheter and three-dimensional electroanatomic mapping system Carto3 between June 2019 and June 2021 were included retrospectively (n = 27). As a control group, 27 patients with CHD and mapping of AT without CM between March 2016 and June 2019 were included. In total, 54 ablation procedures were performed in 42 patients [median age 35 (interquartile range, IQR 30\u201348) years] and 64 ATs were induced and mapped (thereof 50 AT intraatrial re-entrant tachycardia and 14 AT ectopic AT). The median procedure duration was 180 (120\u2013214) min and median fluoroscopy time was 10 (5.2\u201314) min. Acute success was 100% (27\/27) in the Coherence group and 74% (20\/27) in the non-Coherence group (P = 0.01). During follow-up [median 26 (12\u201345) months], AT recurred in 28\/54 patients, thereof 15 patients needed a re-ablation procedure. Log-rank test showed no difference in recurrence rate between the two groups (P = 0.29). Three minor complications occurred (5.5%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Mapping of AT in patients with CHD using the PENTARAY\u2122 mapping catheter and the CM algorithm led to excellent acute success. All ATs were possible to map and no complications related to the PENTARAY\u2122 mapping catheter were observed. Thus, the use of the CM algorithm represents a promising tool in patients with CHD and complex AT.<\/jats:p><\/jats:sec>","DOI":"10.1093\/europace\/euad024","type":"journal-article","created":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T06:56:16Z","timestamp":1676530576000},"page":"1475-1481","source":"Crossref","is-referenced-by-count":5,"title":["Coherent mapping of atrial tachycardias in patients with congenital heart disease"],"prefix":"10.1093","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7715-2799","authenticated-orcid":false,"given":"Sophia","family":"Klehs","sequence":"first","affiliation":[{"name":"Department for Pediatric Cardiology, University of Leipzig\u2014Heart Center , Str\u00fcmpellstr. 39, Leipzig 04289 , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9676-8994","authenticated-orcid":false,"given":"Christian","family":"Paech","sequence":"additional","affiliation":[{"name":"Department for Pediatric Cardiology, University of Leipzig\u2014Heart Center , Str\u00fcmpellstr. 39, Leipzig 04289 , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7615-014X","authenticated-orcid":false,"given":"Livio","family":"Bertagnolli","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, University of Leipzig\u2014Heart Center , Leipzig , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7957-655X","authenticated-orcid":false,"given":"Franziska","family":"Markel","sequence":"additional","affiliation":[{"name":"Department for Pediatric Cardiology, University of Leipzig\u2014Heart Center , Str\u00fcmpellstr. 39, Leipzig 04289 , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2773-689X","authenticated-orcid":false,"given":"Ingo","family":"D\u00e4hnert","sequence":"additional","affiliation":[{"name":"Department for Pediatric Cardiology, University of Leipzig\u2014Heart Center , Str\u00fcmpellstr. 39, Leipzig 04289 , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roman","family":"Gebauer","sequence":"additional","affiliation":[{"name":"Department for Pediatric Cardiology, University of Leipzig\u2014Heart Center , Str\u00fcmpellstr. 39, Leipzig 04289 , Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,2,16]]},"reference":[{"key":"2023041606542052600_","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1093\/europace\/eux380","article-title":"Arrhythmias in congenital heart disease: a position paper of the European Heart Rhythm Association (EHRA), Association for European Paediatric and Congenital Cardiology (AEPC), and the European Society of Cardiology (ESC) working group on grown-up congenital heart disease, endorsed by HRS, PACES, APHRS, and SOLAECE","volume":"20","author":"Hernandez-Madrid","year":"2018","journal-title":"Europace"},{"key":"2023041606542052600_","doi-asserted-by":"crossref","first-page":"e102","DOI":"10.1016\/j.hrthm.2014.05.009","article-title":"PACES\/HRS expert consensus statement on the recognition and management of arrhythmias in adult congenital heart disease: developed in partnership between the Pediatric and Congenital Electrophysiology Society (PACES) and the Heart Rhythm Society (HRS). Endorsed by the governing bodies of PACES, HRS, the American College of Cardiology (ACC), the American Heart Association (AHA), the European Heart Rhythm Association (EHRA), the Canadian Heart Rhythm Society (CHRS), and the International Society for Adult Congenital Heart Disease (ISACHD)","volume":"11","author":"Khairy","year":"2014","journal-title":"Heart Rhythm"},{"key":"2023041606542052600_","doi-asserted-by":"crossref","first-page":"4153","DOI":"10.1093\/eurheartj\/ehaa701","article-title":"The ESC clinical practice guidelines for the management of adult congenital heart disease 2020","volume":"41","author":"Baumgartner","year":"2020","journal-title":"Eur Heart J"},{"key":"2023041606542052600_","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1111\/jce.15422","article-title":"Repeat radiofrequency catheter ablation of atrial tachycardias in patients with congenital heart disease","volume":"33","author":"Klehs","year":"2022","journal-title":"J Cardiovasc Electrophysiol"},{"key":"2023041606542052600_","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.117.005451","article-title":"Radiofrequency catheter ablation of atrial tachycardias in congenital heart disease: results with special reference to complexity of underlying anatomy","volume":"10","author":"Klehs","year":"2017","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2023041606542052600_","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.jacep.2018.10.011","article-title":"Catheter ablation for atrial tachycardia in adults with congenital heart disease: electrophysiological predictors of acute procedural success and post-procedure atrial tachycardia recurrence","volume":"5","author":"Grubb","year":"2019","journal-title":"JACC Clin Electrophysiol"},{"key":"2023041606542052600_","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1007\/s00392-019-01592-x","article-title":"High density mapping and catheter ablation of atrial tachycardias in adults with congenital heart disease","volume":"109","author":"Krause","year":"2020","journal-title":"Clin Res Cardiol"},{"key":"2023041606542052600_","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1016\/j.jacep.2018.07.002","article-title":"Evaluation of electrophysiological mechanisms of post-surgical atrial tachycardias using an automated ultra-high-density mapping system","volume":"4","author":"Xue","year":"2018","journal-title":"JACC Clin Electrophysiol"},{"key":"2023041606542052600_","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.hrthm.2020.09.016","article-title":"Mapping and ablation of clinical spontaneous perimitral atrial tachycardias using an ultra-high-resolution mapping system","volume":"18","author":"Miyazaki","year":"2021","journal-title":"Heart Rhythm"},{"key":"2023041606542052600_","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1016\/j.jacep.2019.08.001","article-title":"Ultra-high-density activation mapping to aid isthmus identification of atrial tachycardias in congenital heart disease","volume":"5","author":"Martin","year":"2019","journal-title":"JACC Clin Electrophysiol"},{"key":"2023041606542052600_","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.118.006536","article-title":"Activation mapping with integration of vector and velocity information improves the ability to identify the mechanism and location of complex scar-related atrial tachycardias","volume":"11","author":"Anter","year":"2018","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2023041606542052600_","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.010535","article-title":"Characterization of the mechanism and substrate of atrial tachycardia using ultra-high-density mapping in adults with congenital heart disease: impact on clinical outcomes","volume":"8","author":"Mantziari","year":"2019","journal-title":"J Am Heart Assoc"},{"key":"2023041606542052600_","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1111\/jce.14457","article-title":"Identification of critical isthmus using coherent mapping in patients with scar-related atrial tachycardia","volume":"31","author":"Vicera","year":"2020","journal-title":"J Cardiovasc Electrophysiol"},{"key":"2023041606542052600_","doi-asserted-by":"crossref","first-page":"i43","DOI":"10.1093\/europace\/euy188","article-title":"An initial experience of high-density mapping-guided ablation in a cohort of patients with adult congenital heart disease","volume":"21","author":"Ernst","year":"2019","journal-title":"Europace"},{"key":"2023041606542052600_","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1093\/europace\/eux180","article-title":"Intra-atrial re-entrant tachycardia in patients with congenital heart disease: factors associated with disease severity","volume":"20","author":"Roca-Luque","year":"2018","journal-title":"Europace"},{"key":"2023041606542052600_","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1161\/CIRCEP.115.003272","article-title":"Time course of atrial fibrillation in patients with congenital heart defects","volume":"8","author":"Teuwen","year":"2015","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2023041606542052600_","doi-asserted-by":"crossref","first-page":"2481","DOI":"10.1016\/j.ijcard.2013.03.004","article-title":"Substrates of atrial arrhythmias: histological insights from patients with congenital heart disease","volume":"168","author":"Ueda","year":"2013","journal-title":"Int J Cardiol"},{"key":"2023041606542052600_","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1161\/CIRCEP.109.909838","article-title":"Long-term outcome after ablative therapy of postoperative atrial tachyarrhythmia in patients with congenital heart disease and characteristics of atrial tachyarrhythmia recurrences","volume":"3","author":"de Groot","year":"2010","journal-title":"Circ Arrhythm Electrophysiol"}],"container-title":["EP Europace"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/europace\/article-pdf\/25\/4\/1475\/49919590\/euad024.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/europace\/article-pdf\/25\/4\/1475\/49919590\/euad024.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T14:34:18Z","timestamp":1701786858000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/europace\/article\/25\/4\/1475\/7040890"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,16]]},"references-count":18,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,2,16]]},"published-print":{"date-parts":[[2023,4,15]]}},"URL":"https:\/\/doi.org\/10.1093\/europace\/euad024","relation":{},"ISSN":["1099-5129","1532-2092"],"issn-type":[{"value":"1099-5129","type":"print"},{"value":"1532-2092","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,4,28]]},"published":{"date-parts":[[2023,2,16]]}}}