{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:35:56Z","timestamp":1792035356345,"version":"4.4.0"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T00:00:00Z","timestamp":1676505600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Patients who undergo permanent pacemaker (PPM) implantation after transcatheter aortic valve replacement (TAVR) have a worse outcome. The aim of this study was to identify risk factors of worse outcomes in patients with post-TAVR PPM implantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>This is a single-centre, retrospective study of consecutive patients who underwent post-TAVR PPM implantation from 11 March 2011 to 9 November 2019. Clinical outcomes were evaluated by landmark analysis with cut-off at 1 year after the PPM implantation. Of the 1389 patients underwent TAVR during the study duration and a total of 110 patients were included in the final analysis. Right ventricular pacing burden (RVPB) \u2265 30% at 1 year was associated with a higher likelihood of heart failure (HF) readmission [adjusted hazard ratio (aHR): 6.333; 95% confidence interval [CI]: 1.417\u201328.311; P = 0.016] and composite endpoint of overall death and\/or HF (aHR: 2.453; 95% CI: 1.040\u20135.786; P = 0.040). The RVPB \u226530% at 1 year was associated with higher atrial fibrillation burden (24.1 \u00b1 40.6% vs. 1.2 \u00b1 5.3%; P = 0.013) and a decrease in left ventricular ejection fraction (\u22125.0 \u00b1 9.8% vs. + 1.1 \u00b1 7.9%; P = 0.005). The predicting factors of the RVPB \u226530% at 1 year were the presence of RVPB \u226540% at 1 month and the valve implantation depth measured from non-coronary cusp \u22654.0 mm (aHR: 57.808; 95% CI: 12.489\u2013267.584; P &amp;lt; 0.001 and aHR: 6.817; 95% CI: 1.829\u201325.402; P = 0.004).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The RVPB \u226530% at 1 year was associated with worse outcomes. Clinical benefit of minimal RV pacing algorithms and biventricular pacing needs to be investigated.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/europace\/euad025","type":"journal-article","created":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T17:24:57Z","timestamp":1675099497000},"page":"1441-1450","source":"Crossref","is-referenced-by-count":24,"title":["Clinical impact of right ventricular pacing burden in patients with post-transcatheter aortic valve replacement permanent pacemaker implantation"],"prefix":"10.1093","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0190-7555","authenticated-orcid":false,"given":"Takahiro","family":"Tsushima","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Cardiology, University Hospitals Harrington Heart & Vascular Institute, Case Western Reserve University School of Medicine , 11100 Euclid Avenue, Cleveland, OH 44106 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadeer","family":"Al-Kindi","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, University Hospitals Harrington Heart & Vascular Institute, Case Western Reserve University School of Medicine , 11100 Euclid Avenue, Cleveland, OH 44106 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis Augusto","family":"Palma Dallan","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, University Hospitals Harrington Heart & Vascular Institute, Case Western Reserve University School of Medicine , 11100 Euclid Avenue, Cleveland, OH 44106 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anas","family":"Fares","sequence":"additional","affiliation":[{"name":"Department of Medicine, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine , Cleveland, OH , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0465-7061","authenticated-orcid":false,"given":"Sung-Han","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, University Hospitals Harrington Heart & Vascular Institute, Case Western Reserve University School of Medicine , 11100 Euclid Avenue, Cleveland, OH 44106 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5543-5990","authenticated-orcid":false,"given":"Heather L","family":"Wheat","sequence":"additional","affiliation":[{"name":"Department of Medicine, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine , Cleveland, OH , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilherme F","family":"Attizzani","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, University Hospitals Harrington Heart & Vascular Institute, Case Western Reserve University School of Medicine , 11100 Euclid Avenue, Cleveland, OH 44106 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2001-332X","authenticated-orcid":false,"given":"Cristian R","family":"Baeza","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Cardiac Surgery, University Hospitals Harrington Heart & Vascular Institute, Case Western Reserve University School of Medicine , Cleveland, OH , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1507-5489","authenticated-orcid":false,"given":"Marc P","family":"Pelletier","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Cardiac Surgery, University Hospitals Harrington Heart & Vascular Institute, Case Western Reserve University School of Medicine , Cleveland, OH , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauricio S","family":"Arruda","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, University Hospitals Harrington Heart & Vascular Institute, Case Western Reserve University School of Medicine , 11100 Euclid Avenue, Cleveland, OH 44106 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4324-0226","authenticated-orcid":false,"given":"Judith A","family":"Mackall","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, University Hospitals Harrington Heart & Vascular Institute, Case Western Reserve University School of Medicine , 11100 Euclid Avenue, Cleveland, OH 44106 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1494-1130","authenticated-orcid":false,"given":"Sergio G","family":"Thal","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, University Hospitals Harrington Heart & Vascular Institute, Case Western Reserve University School of Medicine , 11100 Euclid Avenue, Cleveland, OH 44106 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,2,16]]},"reference":[{"key":"2023041606543271900_","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.jcin.2020.09.063","article-title":"Incidence, predictors, and implications of permanent pacemaker requirement after transcatheter aortic valve replacement","volume":"14","author":"Sammour","year":"2021","journal-title":"JACC Cardiovasc Interv"},{"key":"2023041606543271900_","doi-asserted-by":"crossref","first-page":"2189","DOI":"10.1016\/j.jcin.2016.07.026","article-title":"Incidence, predictors, and outcomes of permanent pacemaker implantation following transcatheter aortic valve 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