{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T06:17:34Z","timestamp":1764569854613,"version":"3.41.2"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T00:00:00Z","timestamp":1679270400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,5,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>In a recent position paper, the European Heart Rhythm Association (EHRA) proposed an algorithm for the screening and management of arrhythmias using digital devices. In patients with prior stroke, a systematic screening approach for atrial fibrillation (AF) should always be implemented, preferably immediately after the event. Patients with increasing age and with specific cardiovascular or non-cardiovascular comorbidities are also deemed to be at higher risk. From a large nationwide database, the aim was to analyse AF incidence rates derived from this new EHRA algorithm.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>Using the French administrative hospital discharge database, all patients hospitalized in 2012 without a history of AF, and with at least a 5-year follow-up (FU) (or if they died earlier), were included. The yearly incidence of AF was calculated in each subgroup defined by the algorithm proposed by EHRA based on a history of previous stroke, increasing age, and eight comorbidities identified via International Classification of Diseases 10th Revision codes. Out of the 4526 104 patients included (mean age 58.9 \u00b1 18.9 years, 64.5% women), 1% had a history of stroke. Among those with no history of stroke, 18% were aged 65\u201374 years and 21% were \u226575 years. During FU, 327 012 patients had an incidence of AF (yearly incidence 1.86% in the overall population). Implementation of the EHRA algorithm divided the population into six risk groups: patients with a history of stroke (group 1); patients &amp;gt; 75 years (group 2); patients aged 65\u201374 years with or without comorbidity (groups 3a and 3b); and patients &amp;lt; 65 years with or without comorbidity (groups 4a and 4b). The yearly incidences of AF were 4.58% per year (group 2), 6.21% per year (group 2), 3.50% per year (group 3a), 2.01% per year (group 3b), 1.23% per year (group 4a), and 0.35% per year (group 4b). In patients aged &amp;lt; 65 years, the annual incidence of AF increased progressively according to the number of comorbidities from 0.35% (no comorbidities) to 9.08% (eight comorbidities). For those aged 65\u201375 years, the same trend was observed, i.e. increasing from 2.01% (no comorbidities) to 11.47% (eight comorbidities).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>These findings at a nationwide scale confirm the relevance of the subgroups in the EHRA algorithm for identifying a higher risk of AF incidence, showing that older patients (&amp;gt;75 years, regardless of comorbidities) have a higher incidence of AF than those with prior ischaemic stroke. Further studies are needed to evaluate the usefulness of algorithm-based risk stratification strategies for AF screening and the impact of screening on major cardiovascular event rates.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/europace\/euad063","type":"journal-article","created":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T13:30:40Z","timestamp":1679319040000},"source":"Crossref","is-referenced-by-count":5,"title":["Incidence of clinical atrial fibrillation and related complications using a screening algorithm at a nationwide level"],"prefix":"10.1093","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1865-5756","authenticated-orcid":false,"given":"Antoine","family":"Roger","sequence":"first","affiliation":[{"name":"Department of Cardiology, Centre Hospitalier Universitaire Dijon Bourgogne , Dijon , France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5176-5121","authenticated-orcid":false,"given":"Yves","family":"Cottin","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Centre Hospitalier Universitaire Dijon Bourgogne , Dijon , France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2720-574X","authenticated-orcid":false,"given":"Sid Ahmed","family":"Bentounes","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Centre Hospitalier Universitaire Trousseau and University Fran\u00e7ois Rabelais , Tours , France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3449-1800","authenticated-orcid":false,"given":"Arnaud","family":"Bisson","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Centre Hospitalier Universitaire Trousseau and University Fran\u00e7ois Rabelais , Tours , France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6544-3916","authenticated-orcid":false,"given":"Alexandre","family":"Bodin","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Centre Hospitalier Universitaire Trousseau and University Fran\u00e7ois Rabelais , Tours , France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0373-9591","authenticated-orcid":false,"given":"Julien","family":"Herbert","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Centre Hospitalier Universitaire Trousseau and University Fran\u00e7ois Rabelais , Tours , France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2639-9593","authenticated-orcid":false,"given":"Baptiste","family":"Maille","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Assistance Publique Hopitaux de Marseille and Aix-Marseille University , Marseille , France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5763-4579","authenticated-orcid":false,"given":"Marianne","family":"Zeller","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Centre Hospitalier Universitaire Dijon Bourgogne , Dijon , France"},{"name":"PEC2, EA 7460, UFR sciences de sant\u00e9, Universit\u00e9 Bourgogne Franche Comt\u00e9 , Dijon , France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1534-3845","authenticated-orcid":false,"given":"Jean Claude","family":"Deharo","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Assistance Publique Hopitaux de Marseille and Aix-Marseille University , Marseille , France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7566-1626","authenticated-orcid":false,"given":"Gregory Y H","family":"Lip","sequence":"additional","affiliation":[{"name":"Liverpool Centre for Cardiovascular Sciences at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital , Thomas Drive, Liverpool L14 3PE , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9267-1658","authenticated-orcid":false,"given":"Laurent","family":"Fauchier","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Centre Hospitalier Universitaire Trousseau and University Fran\u00e7ois Rabelais , Tours , France"},{"name":"Department of Cardiology, Assistance Publique Hopitaux de Marseille and Aix-Marseille University , Marseille , France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,3,20]]},"reference":[{"key":"2023053008420582300_euad063-B1","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1093\/europace\/euac038","article-title":"How to use digital devices to detect and manage arrhythmias: an EHRA practical guide","volume":"24","author":"Svennberg","year":"2022","journal-title":"Europace"},{"key":"2023053008420582300_euad063-B2","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1055\/a-1346-2899","article-title":"Atrial fibrillation in patients with embolic stroke of undetermined source during 3 years of prolonged monitoring with an implantable loop recorder","volume":"121","author":"Kitsiou","year":"2021","journal-title":"Thromb Haemost"},{"key":"2023053008420582300_euad063-B3","doi-asserted-by":"crossref","DOI":"10.1093\/europace\/euac237","article-title":"Global burden of atrial fibrillation\/atrial flutter and its attributable risk factors from 1990 to 2019","author":"Dong","year":"2023","journal-title":"Europace"},{"key":"2023053008420582300_euad063-B4","article-title":"Contemporary management of atrial fibrillation and the predicted vs. absolute risk of ischaemic stroke despite treatment: a report from ESC-EHRA EORP-AF long-term general registry","author":"Ding","year":"2022","journal-title":"Europace"},{"key":"2023053008420582300_euad063-B5","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1016\/j.jclinepi.2010.11.015","article-title":"Hospital discharge data can be used for monitoring procedures and intensive care related to severe maternal morbidity","volume":"64","author":"Chantry","year":"2011","journal-title":"J Clin Epidemiol"},{"key":"2023053008420582300_euad063-B6","first-page":"419","article-title":"Improvement of the quality of medical databases: data-mining-based prediction of diagnostic codes from previous patient codes","volume":"210","author":"Djennaoui","year":"2015","journal-title":"Stud Health Technol Inform"},{"key":"2023053008420582300_euad063-B7","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1161\/CIRCULATIONAHA.119.043971","article-title":"Impact of sapien 3 balloon-expandable versus evolut R self-expandable transcatheter aortic valve implantation in patients with aortic stenosis: data from a nationwide analysis","volume":"141","author":"Deharo","year":"2020","journal-title":"Circulation"},{"key":"2023053008420582300_euad063-B8","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1161\/CIRCULATIONAHA.113.001874","article-title":"Outcomes after acute myocardial infarction in HIV-infected patients: analysis of data from a French nationwide hospital medical information database","volume":"127","author":"Lorgis","year":"2013","journal-title":"Circulation"},{"key":"2023053008420582300_euad063-B9","doi-asserted-by":"crossref","first-page":"2432","DOI":"10.1161\/STROKEAHA.115.010270","article-title":"Patients with ischemic stroke and incident atrial fibrillation: a nationwide cohort study","volume":"46","author":"Fauchier","year":"2015","journal-title":"Stroke"},{"key":"2023053008420582300_euad063-B10","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s00228-013-1614-5","article-title":"Use of the recommended drug combination for secondary prevention after a first occurrence of acute coronary syndrome in France","volume":"70","author":"Bezin","year":"2014","journal-title":"Eur J Clin Pharmacol"},{"key":"2023053008420582300_euad063-B11","article-title":"Searching for atrial fibrillation: looking harder, looking longer, and in increasingly sophisticated ways","author":"Kalarus","year":"2022","journal-title":"Europace"},{"key":"2023053008420582300_euad063-B12","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1093\/europace\/euab324","article-title":"Estimated incidence of previously undetected atrial fibrillation on a 14-day continuous electrocardiographic monitor and associated risk of stroke","volume":"24","author":"McIntyre","year":"2022","journal-title":"Europace"},{"key":"2023053008420582300_euad063-B13","doi-asserted-by":"crossref","first-page":"e4","DOI":"10.1093\/cvr\/cvab341","article-title":"Atrial fibrillation and stroke: are we looking in the right direction?","volume":"118","author":"Hatem","year":"2022","journal-title":"Cardiovasc Res"},{"key":"2023053008420582300_euad063-B14","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.amjcard.2021.09.013","article-title":"Meta-analysis of randomized clinical trials comparing the impact of implantable loop recorder versus usual care after ischemic stroke for detection of atrial fibrillation and stroke risk","volume":"162","author":"Ko","year":"2022","journal-title":"Am J Cardiol"},{"key":"2023053008420582300_euad063-B15","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1093\/eurheartj\/ehaa612","article-title":"2020 ESC guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European association for cardio-thoracic surgery (EACTS): the task force for the diagnosis and management of atrial fibrillation of the European society of cardiology (ESC) developed with the special contribution of the European heart rhythm association (EHRA) of the ESC","volume":"42","author":"Hindricks","year":"2021","journal-title":"Eur Heart J"},{"key":"2023053008420582300_euad063-B16","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1055\/a-1588-8867","article-title":"Atrial fibrillation detected by single time-point handheld electrocardiogram screening and the risk of ischemic stroke","volume":"122","author":"Sun","year":"2022","journal-title":"Thromb Haemost"},{"key":"2023053008420582300_euad063-B17","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1186\/s12872-021-02415-6","article-title":"Anthropometric measures and the risk of developing atrial fibrillation: a Swedish cohort study","volume":"21","author":"Zia","year":"2021","journal-title":"BMC Cardiovasc Disord"},{"key":"2023053008420582300_euad063-B18","first-page":"1851","article-title":"Screening for atrial fibrillation","volume":"135","author":"Freedman","year":"2017","journal-title":"Circ Am Heart Assoc"},{"key":"2023053008420582300_euad063-B19","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1056\/NEJMoa1901183","article-title":"Large-Scale assessment of a smartwatch to identify atrial fibrillation","volume":"381","author":"Perez","year":"2019","journal-title":"N Engl J Med"},{"key":"2023053008420582300_euad063-B20","doi-asserted-by":"crossref","first-page":"2365","DOI":"10.1016\/j.jacc.2019.08.019","article-title":"Mobile photoplethysmographic technology to detect atrial fibrillation","volume":"74","author":"Guo","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"2023053008420582300_euad063-B21","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.ahj.2021.04.003","article-title":"Rationale and design of a large population study to validate software for the assessment of atrial fibrillation from data acquired by a consumer tracker or smartwatch: the Fitbit Heart study","volume":"238","author":"Lubitz","year":"2021","journal-title":"Am Heart J"},{"key":"2023053008420582300_euad063-B22","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1161\/CIRCULATIONAHA.117.030583","article-title":"Assessment of remote heart rhythm sampling using the AliveCor heart monitor to screen for atrial fibrillation","volume":"136","author":"Halcox","year":"2017","journal-title":"Circulation"},{"key":"2023053008420582300_euad063-B23","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1016\/S0140-6736(21)01698-6","article-title":"Implantable loop recorder detection of atrial fibrillation to prevent stroke (the LOOP study): a randomised controlled trial","volume":"398","author":"Svendsen","year":"2021","journal-title":"Lancet"},{"key":"2023053008420582300_euad063-B24","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1016\/S0140-6736(21)01637-8","article-title":"Clinical outcomes in systematic screening for atrial fibrillation (STROKESTOP): a multicentre, parallel group, unmasked, randomised controlled trial","volume":"398","author":"Svennberg","year":"2021","journal-title":"Lancet"},{"key":"2023053008420582300_euad063-B25","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1093\/europace\/euz255","article-title":"Stepwise mass screening for atrial fibrillation using N-terminal B-type natriuretic peptide: the STROKESTOP II study","volume":"22","author":"Kemp Gudmundsdottir","year":"2020","journal-title":"Europace"},{"key":"2023053008420582300_euad063-B26","doi-asserted-by":"crossref","first-page":"e000102","DOI":"10.1161\/JAHA.112.000102","article-title":"Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population: the CHARGE-AF consortium","volume":"2","author":"Alonso","year":"2013","journal-title":"J Am Heart Assoc"},{"key":"2023053008420582300_euad063-B27","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1016\/j.jacc.2016.06.057","article-title":"Atrial fibrillation and thromboembolism in patients with chronic kidney disease","volume":"68","author":"Lau","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"2023053008420582300_euad063-B28","doi-asserted-by":"crossref","first-page":"e002097","DOI":"10.1161\/JAHA.112.002097","article-title":"Impact of chronic kidney disease on risk of incident atrial fibrillation and subsequent survival in medicare patients","volume":"1","author":"Nelson","year":"2012","journal-title":"J Am Heart Assoc"},{"key":"2023053008420582300_euad063-B29","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1093\/eurheartj\/ehaa822","article-title":"Chronic obstructive pulmonary disease and atrial fibrillation: an interdisciplinary perspective","volume":"42","author":"Simons","year":"2021","journal-title":"Eur Heart J"},{"key":"2023053008420582300_euad063-B30","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.ahj.2016.08.011","article-title":"Impact of chronic obstructive pulmonary disease on prognosis in atrial fibrillation: a report from the EURObservational research programme pilot survey on atrial fibrillation (EORP-AF) general registry","volume":"181","author":"Proietti","year":"2016","journal-title":"Am Heart J"},{"key":"2023053008420582300_euad063-B31","doi-asserted-by":"crossref","first-page":"371","DOI":"10.2147\/COPD.S174443","article-title":"A prospective study of the clinical outcomes and prognosis associated with comorbid COPD in the atrial fibrillation population","volume":"14","author":"Rodr\u00edguez-Ma\u00f1ero","year":"2019","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"2023053008420582300_euad063-B32","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1183\/09031936.03.00051502","article-title":"Reduced lung function and risk of atrial fibrillation in the Copenhagen city heart study","volume":"21","author":"Buch","year":"2003","journal-title":"Eur Respir J"},{"key":"2023053008420582300_euad063-B33","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.amjcard.2011.03.004","article-title":"Meta-Analysis of cohort and case\u2013control studies of type 2 diabetes Mellitus and risk of atrial fibrillation","volume":"108","author":"Huxley","year":"2011","journal-title":"Am J Cardiol"},{"key":"2023053008420582300_euad063-B34","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1007\/s11606-010-1340-y","article-title":"Diabetes Mellitus, glycemic control, and risk of atrial fibrillation","volume":"25","author":"Dublin","year":"2010","journal-title":"J Gen Intern Med"},{"key":"2023053008420582300_euad063-B35","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1001\/jama.1994.03510350050036","article-title":"Independent risk factors for atrial fibrillation in a population-based cohort: the framingham heart study","volume":"271","author":"Benjamin","year":"1994","journal-title":"JAMA"},{"key":"2023053008420582300_euad063-B36","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1161\/CIRCULATIONAHA.110.009035","article-title":"Absolute and attributable risks of atrial fibrillation in relation to optimal and borderline risk factors","volume":"123","author":"Huxley","year":"2011","journal-title":"Circulation"},{"key":"2023053008420582300_euad063-B37","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1016\/j.jacc.2010.02.029","article-title":"The long- and short-term impact of elevated body mass index on the risk of new atrial fibrillation: the WHS (women\u2019s health study)","volume":"55","author":"Tedrow","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"2023053008420582300_euad063-B38","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.jacc.2006.08.060","article-title":"Obstructive sleep apnea, obesity, and the risk of incident atrial fibrillation","volume":"49","author":"Gami","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"2023053008420582300_euad063-B39","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1161\/CIRCULATIONAHA.115.018614","article-title":"Atrial fibrillation begets heart failure and vice versa","volume":"133","author":"Santhanakrishnan","year":"2016","journal-title":"Circulation"},{"key":"2023053008420582300_euad063-B40","doi-asserted-by":"crossref","first-page":"198","DOI":"10.3390\/jcm10020198","article-title":"The multifaceted interplay between atrial fibrillation and myocardial infarction: a review","volume":"10","author":"Belkouche","year":"2021","journal-title":"J Clin Med"},{"key":"2023053008420582300_euad063-B41","doi-asserted-by":"crossref","first-page":"2030","DOI":"10.1055\/s-0042-1756355","article-title":"Clinical complexity domains, anticoagulation, and outcomes in patients with atrial fibrillation: a report from the GLORIA-AF registry phase II and III","volume":"122","author":"Romiti","year":"2022","journal-title":"Thromb Haemost"},{"key":"2023053008420582300_euad063-B42","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.1111\/dom.14492","article-title":"Metabolically healthy obesity and cardiovascular events: a nationwide cohort study","volume":"23","author":"Fauchier","year":"2021","journal-title":"Diabetes Obes Metab"},{"key":"2023053008420582300_euad063-B43","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1055\/a-1541-3885","article-title":"Risk of ischemic stroke in asymptomatic atrial fibrillation incidentally detected in primary care compared with other clinical presentations","volume":"122","author":"Wallenhorst","year":"2022","journal-title":"Thromb Haemost"},{"key":"2023053008420582300_euad063-B44","first-page":"475","article-title":"Estimating the prevalence of atrial fibrillation in a general population using validated electronic health data","volume":"5","author":"Norberg","year":"2013","journal-title":"Clin Epidemiol"},{"key":"2023053008420582300_euad063-B45","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.acvd.2020.04.006","article-title":"Successful linkage of French large-scale national registry populations to national reimbursement data: improved data completeness and minimized loss to follow-up","volume":"113","author":"Didier","year":"2020","journal-title":"Arch Cardiovasc Dis"}],"container-title":["Europace"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/europace\/article-pdf\/25\/5\/euad063\/50484940\/euad063.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/europace\/article-pdf\/25\/5\/euad063\/50484940\/euad063.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T08:42:45Z","timestamp":1685436165000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/europace\/article\/doi\/10.1093\/europace\/euad063\/7080812"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,20]]},"references-count":45,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5,19]]}},"URL":"https:\/\/doi.org\/10.1093\/europace\/euad063","relation":{},"ISSN":["1099-5129","1532-2092"],"issn-type":[{"type":"print","value":"1099-5129"},{"type":"electronic","value":"1532-2092"}],"subject":[],"published-other":{"date-parts":[[2023,5]]},"published":{"date-parts":[[2023,3,20]]},"article-number":"euad063"}}