{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T02:16:38Z","timestamp":1790734598656,"version":"4.1.0"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T00:00:00Z","timestamp":1688688000000},"content-version":"vor","delay-in-days":6,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC3601303"],"award-info":[{"award-number":["2022YFC3601303"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2020YFC2004803"],"award-info":[{"award-number":["2020YFC2004803"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82270316"],"award-info":[{"award-number":["82270316"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82100326"],"award-info":[{"award-number":["82100326"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82103904"],"award-info":[{"award-number":["82103904"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009592","name":"Beijing Municipal Science and Technology Commission","doi-asserted-by":"publisher","award":["D171100006817001"],"award-info":[{"award-number":["D171100006817001"]}],"id":[{"id":"10.13039\/501100009592","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002888","name":"Beijing Municipal Education Commission","doi-asserted-by":"publisher","award":["KM202210025012"],"award-info":[{"award-number":["KM202210025012"]}],"id":[{"id":"10.13039\/501100002888","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,7,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>After radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF), the effect of very-early (within 48\u2005h) symptomatic recurrence (VESR) on late (after 3 months of RFCA) recurrence (LR) has been seldomly reported. We aimed to explore the relationship between VESR and LR among post-RFCA patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>This was a single-centre prospective cohort study that enrolled 6887 AF patients who received the first RFCA procedure from June 2018 to December 2021 at Beijing Anzhen Hospital. Patients were divided into four groups based on VESR and early (from 48\u2005h to 3 months after RFCA) recurrence (ER): Group A (no VESR, no ER); Group B (VESR but no ER); Group C (ER but no VESR); and Group D (both VESR and ER). Three hundred and thirty (4.79%) patients experienced VESR (Groups B and D). With an average follow-up of 14.7 months after grouping, the Kaplan\u2013Meier curve showed that LR risk in VESR patients was higher than in other patients (log-rank, P &amp;lt; 0.001), and the difference was significant in both paroxysmal (log-rank, P &amp;lt; 0.001) and persistent (log-rank, P &amp;lt; 0.001) AF patients (P for interaction = 0.118). In multivariate analysis, Groups B, C, and D were associated with a 2.161-, 5.409-, and 7.401-fold increase in the risk of LR, respectively. What is more, compared with Group A, VESR-atrial tachycardia and VESR-AF were related to a 3.467- and 5.564-fold LR risk, respectively. In VESR patients, classification based on ER and VESR modes improved the prediction potential of LR risk.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Very-early symptomatic recurrence is associated with an increased risk of LR.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/europace\/euad189","type":"journal-article","created":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T12:47:14Z","timestamp":1688734034000},"source":"Crossref","is-referenced-by-count":9,"title":["Very-early symptomatic recurrence is associated with late recurrence after radiofrequency ablation of atrial fibrillation"],"prefix":"10.1093","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7184-6260","authenticated-orcid":false,"given":"Zhen","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases , No. 2, Anzhen Road, Chao Yang District, Beijing 100029 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0592-6462","authenticated-orcid":false,"given":"Yiwei","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases , No. 2, Anzhen Road, Chao Yang District, Beijing 100029 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufeng","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases , No. 2, Anzhen Road, Chao Yang District, Beijing 100029 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9227-6589","authenticated-orcid":false,"given":"Jue","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases , No. 2, Anzhen Road, Chao Yang District, Beijing 100029 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1138-7960","authenticated-orcid":false,"given":"Chao","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases , No. 2, Anzhen Road, Chao Yang District, Beijing 100029 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liu","family":"He","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases , No. 2, Anzhen Road, Chao Yang District, Beijing 100029 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueyan","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases , No. 2, Anzhen Road, Chao Yang District, Beijing 100029 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Songnan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases , No. 2, Anzhen Road, Chao Yang District, Beijing 100029 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases , No. 2, Anzhen Road, Chao Yang District, Beijing 100029 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenxi","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases , No. 2, Anzhen Road, Chao Yang District, Beijing 100029 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nian","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases , No. 2, Anzhen Road, Chao Yang District, Beijing 100029 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2812-1827","authenticated-orcid":false,"given":"Ribo","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases , No. 2, Anzhen Road, Chao Yang District, Beijing 100029 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4604-5346","authenticated-orcid":false,"given":"Deyong","family":"Long","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases , No. 2, Anzhen Road, Chao Yang District, Beijing 100029 , 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Endorsed and approved by the governing bodies of the American College of Cardiology, the American Heart Association, the European Cardiac Arrhythmia Society, the European Heart Rhythm Association, the Society of Thoracic Surgeons, and the Heart Rhythm Society","volume":"9","author":"Calkins","year":"2007","journal-title":"Europace"},{"key":"2023071215503665400_euad189-B3","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1093\/europace\/euac131","article-title":"The blanking period after atrial fibrillation ablation: an European Heart Rhythm Association survey on contemporary definition and management","volume":"24","author":"Bordignon","year":"2022","journal-title":"Europace"},{"key":"2023071215503665400_euad189-B4","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1093\/eurheartj\/ehaa612","article-title":"2020 ESC guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery 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