{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T13:36:42Z","timestamp":1793194602402,"version":"4.5.0"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2023,8,4]],"date-time":"2023-08-04T00:00:00Z","timestamp":1691107200000},"content-version":"vor","delay-in-days":2,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,8,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>The relationship between local unipolar voltage (UV) in the pulmonary vein (PV)-ostia and left atrial wall thickness (LAWT) and the utility of these parameters as indices of outcome after atrial fibrillation (AF) ablation remain unclear.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>Two-hundred seventy-two AF patients who underwent AF ablation were enrolled. Unipolar voltage of PV-ostia was measured using a CARTO system, and LAWT was measured using computed tomography. The primary endpoint was atrial tachyarrhythmia (ATA) recurrence including AF. The ATA recurrence was documented in 74 patients (ATA-Rec group). The UV and LAWT of the bilateral superior PV roof to posterior and around the right-inferior PV in the ATA-Rec group were significantly greater than in patients without ATA recurrence (ATA-Free group) (P &amp;lt; 0.001). The UV had a strong positive correlation with LAWT (R2 = 0.446, P &amp;lt; 0.001). The UV 2.7\u2005mV and the corresponding LAWT 1.6\u2005mm were determined as the cut-off values for ATA recurrence (P &amp;lt; 0.001, respectively). Multisite LA high UV (HUV, \u22654 areas of &amp;gt;2.7\u2005mV) or multisite LA wall thickening (\u22655 areas of &amp;gt;1.6\u2005mm), defined as LA hypertrophy (LAH), was related to higher ATA recurrence. Among 92 LAH patients, 66 had HUV (LAH-HUV) and the remaining 26 had low UV (LAH-LUV), characterized by history of non-paroxysmal AF and heart failure, reduced LV ejection fraction, or enlarged LA. In addition, LAH-LUV showed the worst ablation outcome, followed by LAH-HUV and No LAH (log-rank P &amp;lt; 0.001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Combining UV and LAWT enables us to stratify recurrence risk and suggest a tailored ablation strategy according to LA tissue properties.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/europace\/euad240","type":"journal-article","created":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T12:13:00Z","timestamp":1691064780000},"source":"Crossref","is-referenced-by-count":8,"title":["Unipolar-voltage-based evaluation of left atrial tissue properties and ablation outcome in patients with atrial fibrillation"],"prefix":"10.1093","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6588-0764","authenticated-orcid":false,"given":"Masashi","family":"Kamioka","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine , 3311-1 Yakushiji, Shimotsuke 329-0498 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5302-2874","authenticated-orcid":false,"given":"Hisaki","family":"Makimoto","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine , 3311-1 Yakushiji, Shimotsuke 329-0498 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8044-1575","authenticated-orcid":false,"given":"Tomonori","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine , 3311-1 Yakushiji, Shimotsuke 329-0498 , 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960-1295 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6983-436X","authenticated-orcid":false,"given":"Naoko","family":"Hijioka","sequence":"additional","affiliation":[{"name":"Cardiovascular Center, Ohta Nishinouchi Hospital , 2-5-20 Nishinouchi, Koriyama 963-8558 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayako","family":"Yokota","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine , 3311-1 Yakushiji, Shimotsuke 329-0498 , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2591-0433","authenticated-orcid":false,"given":"Takahiro","family":"Komori","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine , 3311-1 Yakushiji, Shimotsuke 329-0498 , 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