{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T18:51:45Z","timestamp":1793904705229,"version":"4.8.0"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2023,8,8]],"date-time":"2023-08-08T00:00:00Z","timestamp":1691452800000},"content-version":"vor","delay-in-days":6,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,8,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Heart rate score (HRSc), the per cent of atrial paced and sensed event in the largest 10\u2005b.p.m. rate histogram bin of a pacemaker, predicts survival in patients with cardiac devices. No correlation between HRSc and development of atrial fibrillation (AF) has been reported. In this study, we evaluated the relationship between pacemaker post-implantation HRSc and the incidence of newly developed atrial tachyarrhythmias (ATAs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>Patients with dual-chamber pacemakers, implanted 2013\u201317, with the LATITUDE remote monitoring data with \u2265600 000 beats of histogram data collected at baseline were included (N = 34 543). Heart rate score was determined from the initial 3-month post-implantation histogram data. Patients were excluded if they had ATAs, defined as atrial high-rate episodes &amp;gt;5\u2005min or &amp;gt;1% of right atrial beats &amp;gt;170\u2005b.p.m. during the initial 3 months post-implantation. New ATAs, after the baseline period, were defined by each of the following: &amp;gt;1, &amp;gt;10, or &amp;gt;25% of atrial beats &amp;gt;170\u2005b.p.m. or atrial tachycardia response (ATR) events &amp;gt;24\u2005h. Patients were followed a median of 2.8 (1.0\u20134.0) years. The incidence of ATAs increased in proportion to HRSc (log-rank P-value &amp;lt;0.001), and the initial HRSc \u226570% was associated with increased ATAs by all definitions. Patients with initial HRSc \u226570% were older, had a higher percentage of right atrium pacing (%RA pacing), had a lower percentage of right ventricular pacing (%RV pacing), and were more likely programmed with rate-response vs. subjects with HRSc &amp;lt;70%. Initial HRSc (hazard ratio: 1.07, 95% confidence interval: 1.05\u20131.09; P &amp;lt; 0.0001) independently predicted ATAs after adjusting for age, gender, %RV pacing, and rate-response programming. The %RA pacing and initial HRSc were correlated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Heart rate score independently predicts any subsequent duration of ATAs in pacemaker patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/europace\/euad242","type":"journal-article","created":{"date-parts":[[2023,8,8]],"date-time":"2023-08-08T14:27:10Z","timestamp":1691504830000},"source":"Crossref","is-referenced-by-count":6,"title":["Initial heart rate score predicts new-onset atrial tachyarrhythmias in pacemaker patients"],"prefix":"10.1093","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7269-9808","authenticated-orcid":false,"given":"Katsuhide","family":"Hayashi","sequence":"first","affiliation":[{"name":"Cardiac Electrophysiology and Pacing Section, Department of Cardiovascular Medicine, Cleveland Clinic , 9500 Euclid Avenue Desk J2-2, Cleveland, OH 44195 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruhiko","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Heart Rhythm Management, University of Occupational and Environmental Health , Kitakyushu , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6044-045X","authenticated-orcid":false,"given":"Brian","family":"Olshansky","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine-Cardiovascular Medicine, University of Iowa Hospital and Clinics , Iowa City, IA , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6484-1250","authenticated-orcid":false,"given":"Arjun D","family":"Sharma","sequence":"additional","affiliation":[{"name":"Unaffiliated , Reno, NV , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5231-5563","authenticated-orcid":false,"given":"Paul W","family":"Jones","sequence":"additional","affiliation":[{"name":"Boston Scientific , St. Paul, MN , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1401-6893","authenticated-orcid":false,"given":"Nicholas","family":"Wold","sequence":"additional","affiliation":[{"name":"Boston Scientific , St. Paul, MN , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7859-7834","authenticated-orcid":false,"given":"David","family":"Perschbacher","sequence":"additional","affiliation":[{"name":"Boston Scientific , St. Paul, MN , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritsuko","family":"Kohno","sequence":"additional","affiliation":[{"name":"Department of Heart Rhythm Management, University of Occupational and Environmental Health , Kitakyushu , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2197-6956","authenticated-orcid":false,"given":"Mark","family":"Richards","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yakima Valley Memorial Hospital , Yakima, WA , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8905-9233","authenticated-orcid":false,"given":"Bruce L","family":"Wilkoff","sequence":"additional","affiliation":[{"name":"Cardiac Electrophysiology and Pacing Section, Department of Cardiovascular Medicine, Cleveland Clinic , 9500 Euclid Avenue Desk J2-2, Cleveland, OH 44195 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,8,8]]},"reference":[{"key":"2023082107254793700_euad242-B1","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s10840-021-01091-y","article-title":"Heart rate 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