{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T00:47:06Z","timestamp":1789778826515,"version":"4.0.1"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T00:00:00Z","timestamp":1709856000000},"content-version":"vor","delay-in-days":7,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Division of Cardiology"},{"name":"Department of Medicine and Therapeutics"},{"DOI":"10.13039\/501100004853","name":"Chinese University of Hong Kong","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004853","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Aveir VR performance and predictors for its pacing threshold (PCT) in a real-world cohort were investigated.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Electrical measurements at various stages of an Aveir VR implant were prospectively collected. Predictors for 3-month PCT were studied. A retrospective cohort of consecutive 139 Micra implants was used to compare the PCT evolution. High PCT was defined as \u22651.5\u2005V, using a pulse width of 0.4\u2005ms for Aveir and 0.24\u2005ms for Micra. Excellent PCT was defined as \u22640.5\u2005V at the respective pulse width.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Among the 123 consecutive Aveir VR implant attempts, 122 (99.2%) were successful. The majority were of advanced age (mean 79.7) and small body size (mean BSA 1.60). Two patients (1.6%) experienced complications, including one pericardial effusion after device reposition and one intraoperative device dislodgement. Eighty-eight patients reached a 3-month follow-up. Aveir 3-month PCT was correlated with impedance at mapping (P = 0.015), tether mode (P &amp;lt; 0.001), end-of-procedure (P &amp;lt; 0.001), and mapping PCT (P = 0.035), but not with PCTs after fixation (P &amp;gt; 0.05). Tether mode impedance &amp;gt;470\u2005ohms had 88% sensitivity and 71% specificity in predicting excellent 3-month PCT. Although it is more common for Aveir to have high PCT at end of procedure (11.5% for Aveir and 2.2% for Micra, P = 0.004), the rate at 3\u2005months was similar (2.3% for Aveir and 3.1% for Micra, P = 1.000).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Aveir VR demonstrated satisfactory performance in this high-risk cohort. Pacing thresholds tend to improve to a greater extent than Micra after implantation. The PCT after fixation, even after a waiting period, has limited predictive value for the chronic threshold. Low-mapping PCT and high intraoperative impedance predict chronic low PCT.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/europace\/euae051","type":"journal-article","created":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T18:30:41Z","timestamp":1709922641000},"source":"Crossref","is-referenced-by-count":20,"title":["Aveir VR real-world performance and chronic pacing threshold prediction using mapping and fixation electrical data"],"prefix":"10.1093","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6119-641X","authenticated-orcid":false,"given":"Mark T K","family":"Tam","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong , Shatin, NT , Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2718-6231","authenticated-orcid":false,"given":"Yuet-Wong","family":"Cheng","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Queen Elizabeth Hospital , 30 Gascoigne Road, KLN , Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph Y S","family":"Chan","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital , 30-32 Ngan Shing Street, Shatin, NT , Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chin-Pang","family":"Chan","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital , 30-32 Ngan Shing Street, Shatin, NT , Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex C K","family":"Au","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital , 30-32 Ngan Shing Street, Shatin, NT , Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie W S","family":"Fan","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital , 30-32 Ngan Shing Street, Shatin, NT , Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9276-1127","authenticated-orcid":false,"given":"Thomas M Y","family":"Chim","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Queen Elizabeth Hospital , 30 Gascoigne Road, KLN , Hong 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Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6828-6269","authenticated-orcid":false,"given":"Guang-Ming","family":"Tan","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong , Shatin, NT , Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0430-5752","authenticated-orcid":false,"given":"Bryan P","family":"Yan","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong , Shatin, NT , Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,3,8]]},"reference":[{"key":"2024032716184761700_euae051-B1","first-page":"e382","article-title":"2018 ACC\/AHA\/HRS guideline on the evaluation and 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