{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:10:43Z","timestamp":1791216643633,"version":"4.1.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T00:00:00Z","timestamp":1719273600000},"content-version":"vor","delay-in-days":24,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,6,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Technological advancements have contributed to the enhanced precision and lesion flexibility in pulsed-field ablation (PFA) by integrating a three-dimensional mapping system combined with a point-by-point ablation strategy. Data regarding the feasibility of this technology remain limited to some clinical trials. This study aims to elucidate initial real-world data on catheter ablation utilizing a lattice-tip focal PFA\/radiofrequency ablation (RFA) catheter in patients with persistent atrial fibrillation (AF).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>Consecutive patients who underwent catheter ablation for persistent AF via the lattice-tip PFA\/RFA catheter were enrolled. We evaluated acute procedural data including periprocedural data as well as the clinical follow-up within a 90-day blanking period. In total, 28 patients with persistent AF underwent AF ablation either under general anaesthesia (n = 6) or deep sedation (n = 22). In all patients, pulmonary vein isolation was successfully achieved. Additional linear ablations were conducted in 21 patients (78%) with a combination of successful anterior line (n = 13, 46%) and roof line (n = 19, 68%). The median procedural and fluoroscopic times were 97 (interquartile range, IQR: 80\u2013114) min and 8.5 (IQR: 7.2\u20139.5) min, respectively. A total of 27 patients (96%) were interviewed during the follow-up within the blanking period, and early recurrent AF was documented in four patients (15%) including one case of recurrent AF during the hospital stay. Neither major nor minor procedural complication occurred.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>In terms of real-world data, our data confirmed AF ablation feasibility utilizing the lattice-tip focal PFA\/RFA catheter in patients with persistent AF.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/europace\/euae129","type":"journal-article","created":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T11:23:31Z","timestamp":1719314611000},"source":"Crossref","is-referenced-by-count":13,"title":["Initial real-world data on catheter ablation in patients with persistent atrial fibrillation using the novel lattice-tip focal pulsed-field ablation catheter"],"prefix":"10.1093","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0299-362X","authenticated-orcid":false,"given":"Shota","family":"Tohoku","sequence":"first","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien Med. Klinik III, Markuskrankenhaus , Department of Cardiology, Wilhelm-Epstein Str. 4, 60431 Frankfurt , Germany"},{"name":"Klinik f\u00fcr Rhythmologie, Universit\u00e4tsklinikum Schleswig-Holstein der Universit\u00e4t zu L\u00fcbeck , Ratzeburger Allee 16023538 L\u00fcbeck , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0282-4658","authenticated-orcid":false,"given":"Stefano","family":"Bordignon","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien Med. Klinik III, Markuskrankenhaus , Department of Cardiology, Wilhelm-Epstein Str. 4, 60431 Frankfurt , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4188-3447","authenticated-orcid":false,"given":"David","family":"Schaack","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien Med. Klinik III, Markuskrankenhaus , Department of Cardiology, Wilhelm-Epstein Str. 4, 60431 Frankfurt , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5588-0533","authenticated-orcid":false,"given":"Jun","family":"Hirokami","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien Med. Klinik III, Markuskrankenhaus , Department of Cardiology, Wilhelm-Epstein Str. 4, 60431 Frankfurt , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5234-744X","authenticated-orcid":false,"given":"Lukas","family":"Urbanek","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien Med. Klinik III, Markuskrankenhaus , Department of Cardiology, Wilhelm-Epstein Str. 4, 60431 Frankfurt , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8905-0922","authenticated-orcid":false,"given":"Andrea","family":"Urbani","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien Med. Klinik III, Markuskrankenhaus , Department of Cardiology, Wilhelm-Epstein Str. 4, 60431 Frankfurt , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Kheir","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien Med. Klinik III, Markuskrankenhaus , Department of Cardiology, Wilhelm-Epstein Str. 4, 60431 Frankfurt , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5347-9906","authenticated-orcid":false,"given":"Boris","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien Med. Klinik III, Markuskrankenhaus , Department of Cardiology, Wilhelm-Epstein Str. 4, 60431 Frankfurt , Germany"},{"name":"Universit\u00e4tsklinikum Frankfurt, Medizinische Klinik 3- Klinik f\u00fcr Kardiologie, Frankfurt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2355-6015","authenticated-orcid":false,"given":"Kyoung-Ryul Julian","family":"Chun","sequence":"additional","affiliation":[{"name":"Cardioangiologisches Centrum Bethanien Med. Klinik III, Markuskrankenhaus , Department of Cardiology, Wilhelm-Epstein Str. 4, 60431 Frankfurt , Germany"},{"name":"Klinik f\u00fcr Rhythmologie, Universit\u00e4tsklinikum Schleswig-Holstein der Universit\u00e4t zu L\u00fcbeck , Ratzeburger Allee 16023538 L\u00fcbeck , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,6,25]]},"reference":[{"key":"2024062813301222200_euae129-B1","doi-asserted-by":"crossref","first-page":"e275","DOI":"10.1016\/j.hrthm.2017.05.012","article-title":"2017 HRS\/EHRA\/ECAS\/APHRS\/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation","volume":"14","author":"Calkins","year":"2017","journal-title":"Heart Rhythm"},{"key":"2024062813301222200_euae129-B2","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.jacep.2020.01.002","article-title":"A lattice-tip temperature-controlled radiofrequency ablation catheter: durability of pulmonary vein isolation and linear lesion block","volume":"6","author":"Reddy","year":"2020","journal-title":"JACC Clin Electrophysiol"},{"key":"2024062813301222200_euae129-B3","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1016\/j.jacep.2023.04.002","article-title":"A focal ablation catheter toggling between radiofrequency and pulsed field energy to treat atrial fibrillation","volume":"9","author":"Reddy","year":"2023","journal-title":"JACC Clin Electrophysiol"},{"key":"2024062813301222200_euae129-B4","doi-asserted-by":"crossref","first-page":"e010817","DOI":"10.1161\/CIRCEP.121.010817","article-title":"5S study: safe and simple single shot pulmonary vein isolation with pulsed field ablation using sedation","volume":"15","author":"Schmidt","year":"2022","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2024062813301222200_euae129-B5","doi-asserted-by":"crossref","first-page":"euad185","DOI":"10.1093\/europace\/euad185","article-title":"European real-world outcomes with Pulsed field ablatiOn in patients with symptomatic atRIAl fibrillation: lessons from the multi-centre EU-PORIA registry","volume":"25","author":"Schmidt","year":"2023","journal-title":"Europace"},{"key":"2024062813301222200_euae129-B6","doi-asserted-by":"crossref","first-page":"e008718","DOI":"10.1161\/CIRCEP.120.008718","article-title":"Lattice-Tip focal ablation catheter that toggles between radiofrequency and pulsed field energy to treat atrial fibrillation: a first-in-human trial","volume":"13","author":"Reddy","year":"2020","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2024062813301222200_euae129-B7","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1161\/CIRCULATIONAHA.123.064959","article-title":"Safety and effectiveness of pulsed field ablation to treat atrial fibrillation: one-year outcomes from the MANIFEST-PF 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