{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T16:34:30Z","timestamp":1793637270575,"version":"4.5.1"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2024,7,12]],"date-time":"2024-07-12T00:00:00Z","timestamp":1720742400000},"content-version":"vor","delay-in-days":11,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Pulsed field ablation (PFA) is a novel, non-thermal, cardiac tissue-selective ablation modality. To date, radiofrequency (RF)-guided high-power short-duration (HPSD) ablation represents the gold standard besides cryo-ablation for pulmonary vein isolation (PVI). This single-centre, retrospective study investigated the efficacy of PFA-PVI vs. HPSD-RF PVI in terms of single-procedure arrhythmia-free outcome and safety in a real-world setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>Consecutive, paroxysmal atrial fibrillation (AF) patients who underwent PVI using PFA or HPSD-RF were enrolled. In group PFA, PVI was performed using a pentaspline PFA catheter. The ablation procedure in group HPSD-RF was performed with RF energy (45 W, ablation index). A total of 410 patients (group PFA, 201; group HPSD-RF, 209) were included. There was no difference between both groups regarding age, gender, and CHA2DS2-VASc score. The procedure time was significantly shorter in group PFA [61 (44\u2013103) vs. 125 (105\u2013143) min; P &amp;lt; 0.001]; fluoroscopy time and dose area product were significantly higher in group PFA [16 (13\u201320) vs. 4 (2\u20135) min; P &amp;lt; 0.01 and 412 (270\u2013739) vs. 129 (58\u2013265) \u03bcGym2; P &amp;lt; 0.01]. The overall complication rates were 2.9% in group PFA and 6.2% in group HPSD (P = 0.158). There was one fatal stroke in the PFA group. The 1-year Kaplan\u2013Meier estimated freedom from any atrial tachyarrhythmia was 85% with PFA and 79% with HPSD-RF (log-rank P = 0.160). In 56 repeat ablation procedures, the PV reconnection rate was 30% after PFA and 38% after HPSD-RF (P = 0.372).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Both PFA and HPSD-RF were highly efficient and effective in achieving PVI in paroxysmal AF patients. The arrhythmia-free survival is comparable. The PV reconnection rate was not different.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/europace\/euae194","type":"journal-article","created":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T14:42:59Z","timestamp":1720708979000},"source":"Crossref","is-referenced-by-count":31,"title":["Pulmonary vein isolation using pulsed field ablation vs. high-power short-duration radiofrequency ablation in paroxysmal atrial fibrillation: efficacy, safety, and long-term follow-up (PRIORI study)"],"prefix":"10.1093","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7385-2691","authenticated-orcid":false,"given":"Nico","family":"Reinsch","sequence":"first","affiliation":[{"name":"Department of Electrophysiology, Alfried Krupp Krankenhaus , Alfried-Krupp-Stra\u00dfe 21, 45131 Essen , Germany"},{"name":"Department of Medicine, Witten\/Herdecke University , Alfred-Herrhausen-Stra\u00dfe 50, 58448 Witten , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2116-1690","authenticated-orcid":false,"given":"Anna","family":"F\u00fcting","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, Alfried Krupp Krankenhaus , Alfried-Krupp-Stra\u00dfe 21, 45131 Essen , Germany"},{"name":"Department of Medicine, Witten\/Herdecke University , Alfred-Herrhausen-Stra\u00dfe 50, 58448 Witten , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7784-762X","authenticated-orcid":false,"given":"Stefan","family":"Hartl","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, Alfried Krupp Krankenhaus , Alfried-Krupp-Stra\u00dfe 21, 45131 Essen , Germany"},{"name":"Department of Medicine, Witten\/Herdecke University , Alfred-Herrhausen-Stra\u00dfe 50, 58448 Witten , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3827-458X","authenticated-orcid":false,"given":"Dennis","family":"H\u00f6wel","sequence":"additional","affiliation":[{"name":"Department of Medicine, Witten\/Herdecke University , Alfred-Herrhausen-Stra\u00dfe 50, 58448 Witten , Germany"},{"name":"Department of Cardiology, St. Marienhospital Vechta , Vechta , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Rausch","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, Alfried Krupp Krankenhaus , Alfried-Krupp-Stra\u00dfe 21, 45131 Essen , Germany"},{"name":"Department of Medicine, Witten\/Herdecke University , Alfred-Herrhausen-Stra\u00dfe 50, 58448 Witten , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yali","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology, Alfried Krupp Krankenhaus , 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