{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T01:29:37Z","timestamp":1780363777864,"version":"3.54.1"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T00:00:00Z","timestamp":1722902400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,30]]},"abstract":"Abstract<\/jats:title>\n \n Aims<\/jats:title>\n The study evaluated the positivity rate, haemodynamic responses, and prognosis in terms of syncopal recurrence among patients with situational syncope (SS) stratified according to the underlying situational triggers.<\/jats:p>\n <\/jats:sec>\n \n Methods and results<\/jats:title>\n We retrospectively evaluated all consecutive patients with SS who underwent nitroglycerine (NTG)-potentiated head-up tilt test (HUTT) at Syncope Unit of the University of Campania \u2018Luigi Vanvitelli\u2019\u2014Monaldi Hospital from 1 March 2017 to 1 May 2023. All patients were followed for at least one year. The study population was divided according to the underlying triggers (micturition, swallow, defaecation, cough\/sneeze, post-exercise). Two hundred thirty-six SS patients (mean age 50 \u00b1 19.3 years; male 63.1%) were enrolled; among them, the situational trigger was micturition in 109 patients (46.2%); swallow in 32 (13.6%) patients; defaecation in 35 (14.8%) patients; post-exercise in 41 (17.4%) patients; and cough\/sneeze in 17 (7.2%) patients. There were no significant differences in baseline clinical characteristics and HUTT responses between different situational triggers. The Kaplan\u2013Meier analysis did not show a statistically different rate of syncope recurrence across patients stratified by baseline situational triggers (log-rank P = 0.21).<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Situational syncope appears to be a homogenous syndrome, and different triggers do not impact the HUTT response or syncope recurrence at 1 year.<\/jats:p>\n <\/jats:sec>","DOI":"10.1093\/europace\/euae208","type":"journal-article","created":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T03:34:59Z","timestamp":1723001699000},"source":"Crossref","is-referenced-by-count":3,"title":["The triggers of situational syncope do not influence the head-up tilt test response and prognosis"],"prefix":"10.1093","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9227-0360","authenticated-orcid":false,"given":"Vincenzo","family":"Russo","sequence":"first","affiliation":[{"name":"Cardiology and Syncope Unit, Department of Translational Medical Sciences, University of Campania \u2018Luigi Vanvitelli\u2019\u2014Monaldi Hospital , 80131, Naples ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1246-4876","authenticated-orcid":false,"given":"Erika","family":"Parente","sequence":"additional","affiliation":[{"name":"Cardiology and Syncope Unit, Department of Translational Medical Sciences, University of Campania \u2018Luigi Vanvitelli\u2019\u2014Monaldi Hospital , 80131, Naples ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2619-8368","authenticated-orcid":false,"given":"Angelo","family":"Comune","sequence":"additional","affiliation":[{"name":"Cardiology and Syncope Unit, Department of Translational Medical Sciences, University of Campania \u2018Luigi Vanvitelli\u2019\u2014Monaldi Hospital , 80131, Naples ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2632-1262","authenticated-orcid":false,"given":"Anna","family":"Rago","sequence":"additional","affiliation":[{"name":"Cardiology and Syncope Unit, Department of Translational Medical Sciences, University of Campania \u2018Luigi Vanvitelli\u2019\u2014Monaldi Hospital , 80131, Naples ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1776-8449","authenticated-orcid":false,"given":"Gerardo","family":"Nigro","sequence":"additional","affiliation":[{"name":"Cardiology and Syncope Unit, Department of Translational Medical Sciences, University of Campania \u2018Luigi Vanvitelli\u2019\u2014Monaldi Hospital , 80131, Naples ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1845-5607","authenticated-orcid":false,"given":"Michele","family":"Brignole","sequence":"additional","affiliation":[{"name":"IRCCS Istituto Auxologico Italiano, Faint & Fall Research Centre, Department of Cardiology, S. Luca Hospital , 20149, Milan ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,8,6]]},"reference":[{"key":"2024093009365148200_euae208-B1","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1093\/eurheartj\/ehy037","article-title":"2018 ESC guidelines for the diagnosis and management of syncope","volume":"39","author":"Brignole","year":"2018","journal-title":"Eur Heart J"},{"key":"2024093009365148200_euae208-B2","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1136\/heartjnl-2023-322943","article-title":"Clinical features and response at head-up tilt test of patients with situational syncope","volume":"110","author":"Russo","year":"2023","journal-title":"Heart"},{"key":"2024093009365148200_euae208-B3","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1136\/heartjnl-2023-323180","article-title":"Situational vs vasovagal syncope: one but different?","volume":"110","author":"Johansson","year":"2023","journal-title":"Heart"},{"key":"2024093009365148200_euae208-B4","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.1093\/eurheartj\/ehad322","article-title":"Short-duration head-up tilt test potentiated with sublingual nitroglycerin in suspected vasovagal syncope: the fast Italian protocol","volume":"44","author":"Russo","year":"2023","journal-title":"EurHeart J"},{"key":"2024093009365148200_euae208-B5","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1053\/eupc.1999.0064","article-title":"New classification of haemodynamics of vasovagal syncope: beyond the VASIS classification. Analysis of the pre-syncopal phase of the tilt test without and with nitroglycerin challenge","volume":"2","author":"Brignole","year":"2000","journal-title":"Europace"}],"container-title":["Europace"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/europace\/advance-article-pdf\/doi\/10.1093\/europace\/euae208\/58745109\/euae208.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/europace\/article-pdf\/26\/9\/euae208\/59443910\/euae208.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/europace\/article-pdf\/26\/9\/euae208\/59443910\/euae208.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T09:36:59Z","timestamp":1727689019000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/europace\/article\/doi\/10.1093\/europace\/euae208\/7728004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,6]]},"references-count":5,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,8,30]]}},"URL":"https:\/\/doi.org\/10.1093\/europace\/euae208","relation":{},"ISSN":["1099-5129","1532-2092"],"issn-type":[{"value":"1099-5129","type":"print"},{"value":"1532-2092","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,9]]},"published":{"date-parts":[[2024,8,6]]},"article-number":"euae208"}}