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Arrhythmias predispose these patients to additional risk and are associated with considerable morbidity from recurrent implantable cardioverter-defibrillator shocks, progressive failure of the unsupported right ventricle, and herald an increased risk of mortality. Management of patients with arrhythmias and LVAD differs in many aspects from the general population heart failure patients. These include ruling out the reversible causes of arrhythmias that in LVAD patients may include mechanical irritation from the inflow cannula and suction events. For patients with symptomatic arrhythmias refractory to medical treatment, catheter ablation might be relevant. There are specific technical and procedural challenges perceived to be unique to LVAD-related ventricular tachycardia (VT) ablation such as vascular and LV access, signal filtering, catheter manoeuvrability within decompressed chambers, and electroanatomic mapping system interference. In some patients, the arrhythmogenic substrate might not be readily accessible by catheter ablation after LVAD implantation. In this regard, the peri-implantation period offers a unique opportunity to surgically address arrhythmogenic substrate and suppress future VT recurrences. This document aims to address specific aspects of the management of arrhythmias in LVAD patients focusing on anti-arrhythmic drug therapy and ablations.<\/jats:p>","DOI":"10.1093\/europace\/euae272","type":"journal-article","created":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T00:20:00Z","timestamp":1730161200000},"source":"Crossref","is-referenced-by-count":24,"title":["Drug therapy and catheter ablation for management of arrhythmias in continuous flow left ventricular assist device\u2019s patients: a Clinical Consensus Statement of the European Heart Rhythm Association and the Heart Failure Association of the ESC"],"prefix":"10.1093","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5625-0071","authenticated-orcid":false,"given":"Petr","family":"Peichl","sequence":"first","affiliation":[{"name":"Department of Cardiology, IKEM , V\u00edde\u0148sk\u00e1 1958\/9, Prague ,","place":["Czech Republic"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3044-197X","authenticated-orcid":false,"given":"Antoni","family":"Bayes-Genis","sequence":"additional","affiliation":[{"name":"Heart Institute at Hospital Universitari Germans Trias i Pujol, CIBERCV , Badalona ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1379-1684","authenticated-orcid":false,"given":"Thomas","family":"Deneke","sequence":"additional","affiliation":[{"name":"Clinic for Arrhythmology, Klinikum Nuernberg S\u00fcd, University Hospital of the Paracelsus Medical University , Nuernberg ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3197-3628","authenticated-orcid":false,"given":"Ovidiu","family":"Chioncel","sequence":"additional","affiliation":[{"name":"Institute of Emergency for Cardiovascular Diseases, \u2018C.C.Iliescu\u2019 \u00a0 Bucharest ,","place":["Romania"]},{"name":"University of Medicine Carol Davila , Bucharest ,","place":["Romania"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5878-6750","authenticated-orcid":false,"given":"Marta","family":"deRiva","sequence":"additional","affiliation":[{"name":"Leiden University Medical Center , Leiden ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3085-167X","authenticated-orcid":false,"given":"Maria Generosa","family":"Crespo-Leiro","sequence":"additional","affiliation":[{"name":"Complexo Hospitalario Universitario A Coru\u00f1a (CHUAC)-CIBERCV, Instituto de Investigaci\u00f3n Biomedica A Coru\u00f1a (INIBIC), Universidad de A Coru\u00f1a (UDC) , A Coru\u00f1a ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0372-4480","authenticated-orcid":false,"given":"Antonio","family":"Frontera","sequence":"additional","affiliation":[{"name":"Department of Cardiac Electrophysiology, Great Metropolitan Hospital Niguarda , Milan ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2144-341X","authenticated-orcid":false,"given":"Finn","family":"Gustafsson","sequence":"additional","affiliation":[{"name":"Department of Cardiology , Rigshospitalet ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5716-6712","authenticated-orcid":false,"given":"Rapha\u00ebl P","family":"Martins","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital of Rennes , Rennes ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9298-7871","authenticated-orcid":false,"given":"Matteo","family":"Pagnesi","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Specialties, Radiological sciences and Public Health, Institute of Cardiology, ASST Spedali Civili, University of Brescia , Brescia ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4800-1841","authenticated-orcid":false,"given":"Philippe","family":"Maury","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rangueil Hospital of Toulouse , Toulouse ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6333-9496","authenticated-orcid":false,"given":"Mark C","family":"Petrie","sequence":"additional","affiliation":[{"name":"School of Cardiovascular and Medical Sciences, University of Glasgow , Glasgow ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8348-9320","authenticated-orcid":false,"given":"Frederic","family":"Sacher","sequence":"additional","affiliation":[{"name":"Cardiac Arrhythmia Department, Univ. 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