{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T21:06:48Z","timestamp":1771708008196,"version":"3.50.1"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T00:00:00Z","timestamp":1730160000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>The use of ultrasound (US)-guided venous puncture for cardiac pacing\/defibrillation lead placement may minimize the risk of periprocedural complications and radiation exposure. However, none of the published studies have been sufficiently powered to recommend this approach as the standard of care. We compare the safety and efficacy of ultrasound-guided axillary venous puncture (US-AVP) vs. fluoroscopy-guided access for cardiac implantable electronic devices (CIEDs) by performing an individual patient data meta-analysis based on previously published studies.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>We conducted a thorough literature search encompassing longitudinal investigations (five randomized and one prospective studies) reporting data on X-ray-guided and US-AVP for CIED procedures. The primary endpoint was to compare the safety of the two techniques. Secondary endpoints included the success rate of each technique, the necessity of switching to alternative methods, the time needed to obtain venous access, X-ray exposure, and the occurrence of periprocedural complications. Six longitudinal eligible studies were identified including 700 patients (mean age 74.9 \u00b1 12.1 years, 68.4% males). The two approaches for venous cannulation showed a similar success rate. The use of an X-ray-guided approach significantly increased the risk of inadvertent arterial punctures (OR: 2.15, 95% CI: 2.10\u20132.21, P = 0.003), after adjustment for potential confounders. Conversely, a US-AVP approach reduces time to vascular access, radiation exposure, and the number of attempts to vascular access.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>The US-AVP enhances safety by reducing radiation exposure and time to vascular access while maintaining a low rate of major complications compared to the X-ray-guided approach.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Clinical trial registration<\/jats:title>\n                  <jats:p>PROSPERO identifier: CRD42024539623.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/europace\/euae274","type":"journal-article","created":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T20:16:00Z","timestamp":1730232960000},"source":"Crossref","is-referenced-by-count":6,"title":["Ultrasound-guided vs. fluoro-guided axillary venous access for cardiac implantable electronic devices: a patient-based meta-analysis"],"prefix":"10.1093","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0667-7616","authenticated-orcid":false,"given":"Francesco","family":"Vitali","sequence":"first","affiliation":[{"name":"Cardiology Department, Sant\u2019Anna University Hospital, University of Ferrara , Via Aldo Moro 8, 44124 Cona, Ferrara ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4559-1292","authenticated-orcid":false,"given":"Marco","family":"Zuin","sequence":"additional","affiliation":[{"name":"Cardiology Department, Sant\u2019Anna University Hospital, University of Ferrara , Via Aldo Moro 8, 44124 Cona, Ferrara ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1371-3678","authenticated-orcid":false,"given":"Paul","family":"Charles","sequence":"additional","affiliation":[{"name":"H\u00f4pital de la Croix Rousse, Hospices Civils de Lyon , Lyon ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6258-3999","authenticated-orcid":false,"given":"Javier","family":"Jim\u00e9nez-D\u00edaz","sequence":"additional","affiliation":[{"name":"Arrhythmia Unit, Cardiology Department, Hospital General Universitario of Ciudad Real , Ciudad Real ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0543-2040","authenticated-orcid":false,"given":"Seth H","family":"Sheldon","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, The University of Kansas Medical Center , Kansas City, KS ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5325-4229","authenticated-orcid":false,"given":"Ana Paula","family":"Tagliari","sequence":"additional","affiliation":[{"name":"Program in Cardiology and Cardiovascular Sciences, School of Medicine, Universidade Federal do Rio Grande do Sul , Porto Alegre ,","place":["Brazil"]},{"name":"Department of Cardiovascular Surgery, Hospital M\u00e3e de Deus , Porto Alegre ,","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8574-9421","authenticated-orcid":false,"given":"Federico","family":"Migliore","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padova , Padua ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1972-9665","authenticated-orcid":false,"given":"Michele","family":"Malag\u00f9","sequence":"additional","affiliation":[{"name":"Cardiology Department, Sant\u2019Anna University Hospital, University of Ferrara , Via Aldo Moro 8, 44124 Cona, Ferrara ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathieu","family":"Montoy","sequence":"additional","affiliation":[{"name":"H\u00f4pital de la Croix Rousse, Hospices Civils de Lyon , Lyon ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe Higuera","family":"Sobrino","sequence":"additional","affiliation":[{"name":"Arrhythmia Unit, Cardiology Department, Hospital General Universitario of Ciudad Real , Ciudad Real ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex M","family":"Courtney","sequence":"additional","affiliation":[{"name":"H\u00f4pital de la Croix Rousse, Hospices Civils de Lyon , Lyon ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7839-2054","authenticated-orcid":false,"given":"Adriano Nunes","family":"Kochi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Hospital M\u00e3e de Deus , Porto Alegre ,","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samir","family":"Fareh","sequence":"additional","affiliation":[{"name":"H\u00f4pital de la Croix Rousse, Hospices Civils de Lyon , Lyon ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5285-7140","authenticated-orcid":false,"given":"Matteo","family":"Bertini","sequence":"additional","affiliation":[{"name":"Cardiology Department, Sant\u2019Anna University Hospital, University of Ferrara , Via Aldo Moro 8, 44124 Cona, Ferrara ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,10,29]]},"reference":[{"key":"2024112914592020200_euae274-B1","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1093\/europace\/euaa367","article-title":"EHRA expert consensus statement and practical guide on optimal implantation 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in patients receiving vitamin K antagonist and antiplatelet therapy at the time of pacemaker or cardioverter defibrillator implantation (from the POCKET Study)","volume":"119","author":"Malag\u00f9","year":"2017","journal-title":"Am J Cardiol"},{"key":"2024112914592020200_euae274-B20","doi-asserted-by":"crossref","first-page":"euad191","DOI":"10.1093\/europace\/euad191","article-title":"Practical guidance to reduce radiation exposure in electrophysiology applying ultra low-dose protocols: a European Heart Rhythm Association 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