{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T04:25:18Z","timestamp":1789791918339,"version":"4.0.1"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T00:00:00Z","timestamp":1730764800000},"content-version":"vor","delay-in-days":4,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003348","name":"Fukuda Foundation for Medical Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003348","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Catheter ablation (CA) of idiopathic ventricular arrhythmias (VAs) from the epicardial left ventricular summit is challenging. The endocardial approach targets two sites: the endocardial closest site (ECS) to the epicardial earliest activation site (epi-EAS) and the endocardial earliest activation site (endo-EAS). We aimed to differentiate between cases where CA at the ECS was effective and where CA at the endo-EAS yielded success.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>Fifty-eight patients (47 men; age 60 \u00b1 13 years) were analysed with VAs in which the EAS was observed in the coronary venous system (CVS). Overall, VAs were successfully eliminated in 42 (72%) patients: 8 in the CVS, 8 where the ECS matched with the endo-EAS, 11 at the ECS, and 15 at the endo-EAS. A successful ECS ablation was associated with a shorter epi-EAS\u2013ECS distance (10.2 \u00b1 4.7 vs. 18.8 \u00b1 5.3\u2005mm; P &amp;lt; 0.001) and shorter epi-EAS\u2013left main coronary trunk (LMT) ostial distance (20.3 \u00b1 7.6 vs. 30.3 \u00b1 8.4\u2005mm; P = 0.005), with optimal cut-off values of \u226412.6 and \u226424.0\u2005mm, respectively. A successful endo-EAS ablation was associated with an earlier electrogram at the endo-EAS [23 (8, 36) vs. 15 (0, 19) ms preceding the QRS; P &amp;lt; 0.001] and shorter epi-EAS\u2013endo-EAS interval [6 (1, 8) vs. 22 (12, 25) ms; P &amp;lt; 0.001], with optimal cut-off values of \u226518 and \u22649\u2005ms, respectively.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Shorter anatomical distances between the epi-EAS and ECS, and between the epi-EAS and LMT ostium, predict a successful ECS ablation. The prematurity of the endo-EAS electrogram and a shorter interval between the epi-EAS and endo-EAS predicted a successful endo-EAS ablation.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/europace\/euae278","type":"journal-article","created":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T17:50:32Z","timestamp":1730829032000},"source":"Crossref","is-referenced-by-count":14,"title":["Anatomical vs. electrophysiological approach for ablation of premature ventricular contractions originating from the left ventricular summit (ISESHIMA-SUMMIT Study)"],"prefix":"10.1093","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2664-7139","authenticated-orcid":false,"given":"Ryuta","family":"Watanabe","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Nihon University School of Medicine , 30-1 Ohyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610 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Sapporo ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0226-9073","authenticated-orcid":false,"given":"Takuya","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Clinical Engineering, Sapporo Cardiovascular Clinic, Sapporo Heart Center , Sapporo ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1960-5627","authenticated-orcid":false,"given":"Michifumi","family":"Tokuda","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The Jikei University School of Medicine , Tokyo ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0230-4556","authenticated-orcid":false,"given":"Masato","family":"Fukunaga","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Kokura Memorial Hospital , Kitakyushu ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-5569-972X","authenticated-orcid":false,"given":"Koumei","family":"Onuki","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Kokura Memorial Hospital , Kitakyushu ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5427-5048","authenticated-orcid":false,"given":"Yosuke","family":"Nakatani","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Gunma Prefectural Cardiovascular Center , Maebashi ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2744-0738","authenticated-orcid":false,"given":"Shingo","family":"Yoshimura","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Gunma Prefectural Cardiovascular Center , Maebashi 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