{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:32:23Z","timestamp":1777498343278,"version":"3.51.4"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T00:00:00Z","timestamp":1735257600000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010617","name":"Michael Wolk Heart Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010617","id-type":"DOI","asserted-by":"publisher"}]},{"name":"New York Cardiac Center, Inc."},{"name":"New York Weill Cornell Medical Center Alumni Council"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Utilization of transvenous lead extraction\/removal (TLE) for the management of cardiac implantable electronic device (CIED)-associated infective endocarditis (IE) remains low. The aim of this study was to examine the impact of hospital TLE procedural volume on TLE utilization and outcomes for patients with CIED-associated IE.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>Using the Nationwide Readmissions Database, we evaluated 21 545 admissions for patients (mean age 70 years, 39% female) with CIEDs hospitalized with IE at TLE centres. Hospitals were categorized based on annual volume tertiles: (i) low-volume (1\u201317 TLEs\/year), (ii) medium-volume (18\u201345 TLEs\/year), and (iii) high-volume centres (&amp;gt;45 TLEs\/year). Between 2016 and 2019, 57% of admissions in the study were to low-volume TLE centres. Transvenous lead extraction\/removal was performed during 6.9, 19.3, and 26% of admissions for CIED-associated IE at low-, medium-, and high-volume TLE centres, respectively (P &amp;lt; 0.001). After adjustment for age and comorbidities, hospitalization for IE at high-volume centres was independently associated with TLE when compared with low-volume centres (adjusted odds ratio 4.26; 95% confidence interval 3.53\u20135.15). Transvenous lead extraction\/removal-associated complication rates were similar at 2.5, 2.3, and 3.4% at low-, medium-, and high-volume centres, respectively (P = 0.493). Overall inpatient mortality during admissions to low-, medium-, and high-volume centres was also similar.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Admissions to high-volume TLE centres were associated with higher utilization of TLE for management of CIED-associated IE. Transvenous lead extraction\/removal-associated complications and mortality among patients hospitalized with CIED-associated IE were similar when stratified by hospital TLE volume, but this needs to be considered in context of significant differences in patient comorbidity burden between centres.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/europace\/euae308","type":"journal-article","created":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T10:39:28Z","timestamp":1735295968000},"source":"Crossref","is-referenced-by-count":7,"title":["Impact of hospital lead extraction volume on management of cardiac implantable electronic device-associated infective endocarditis"],"prefix":"10.1093","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0927-357X","authenticated-orcid":false,"given":"Ari G","family":"Mandler","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Weill Cornell Medicine\u2014New York Presbyterian Hospital and Weill Cornell Cardiovascular Outcomes Research Group (CORG) , 520 East 70th Street 4th Floor, New York, NY 10021 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher T","family":"Sciria","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Weill Cornell Medicine\u2014New York Presbyterian Hospital and Weill Cornell Cardiovascular Outcomes Research Group (CORG) , 520 East 70th Street 4th Floor, New York, NY 10021 ,","place":["USA"]},{"name":"Department of Medicine, Division of Cardiology, University of Rochester Medical Center , Rochester, NY ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0317-536X","authenticated-orcid":false,"given":"Edward V","family":"Kogan","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Weill Cornell Medicine\u2014New York Presbyterian Hospital and Weill Cornell Cardiovascular Outcomes Research Group (CORG) , 520 East 70th Street 4th Floor, New York, NY 10021 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8092-108X","authenticated-orcid":false,"given":"Ilya","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Weill Cornell Medicine\u2014New York Presbyterian Hospital and Weill Cornell Cardiovascular Outcomes Research Group (CORG) , 520 East 70th Street 4th Floor, New York, NY 10021 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8825-0757","authenticated-orcid":false,"given":"Ilhwan","family":"Yeo","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Weill Cornell Medicine\u2014New York Presbyterian Hospital and Weill Cornell Cardiovascular Outcomes Research Group (CORG) , 520 East 70th Street 4th Floor, New York, NY 10021 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew S","family":"Simon","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Infectious Diseases, Weill Cornell Medicine\u2014New York Presbyterian Hospital , New York, NY ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9257-6178","authenticated-orcid":false,"given":"Luke K","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Weill Cornell Medicine\u2014New York Presbyterian Hospital and Weill Cornell Cardiovascular Outcomes Research Group (CORG) , 520 East 70th Street 4th Floor, New York, NY 10021 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3461-505X","authenticated-orcid":false,"given":"James E","family":"Ip","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Weill Cornell Medicine\u2014New York Presbyterian Hospital and Weill Cornell Cardiovascular Outcomes Research Group (CORG) , 520 East 70th Street 4th Floor, New York, NY 10021 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8852-4551","authenticated-orcid":false,"given":"Christopher F","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Weill Cornell Medicine\u2014New York Presbyterian Hospital and Weill Cornell Cardiovascular Outcomes Research Group (CORG) , 520 East 70th Street 4th Floor, New York, NY 10021 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven M","family":"Markowitz","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Weill Cornell Medicine\u2014New York Presbyterian Hospital and Weill Cornell Cardiovascular Outcomes Research Group (CORG) , 520 East 70th Street 4th Floor, New York, NY 10021 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce B","family":"Lerman","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Weill Cornell Medicine\u2014New York Presbyterian Hospital and Weill Cornell Cardiovascular Outcomes Research Group (CORG) , 520 East 70th Street 4th Floor, New York, NY 10021 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7158-8305","authenticated-orcid":false,"given":"George","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Weill Cornell Medicine\u2014New York Presbyterian Hospital and Weill Cornell Cardiovascular Outcomes Research Group (CORG) , 520 East 70th Street 4th Floor, New York, NY 10021 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4574-9360","authenticated-orcid":false,"given":"Jim W","family":"Cheung","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, Weill Cornell Medicine\u2014New York Presbyterian Hospital and Weill Cornell Cardiovascular Outcomes Research Group (CORG) , 520 East 70th Street 4th Floor, New York, NY 10021 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,12,27]]},"reference":[{"key":"2025013112550186900_euae308-B1","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/j.jacep.2019.06.016","article-title":"Trends of cardiovascular implantable electronic device infection in 3 decades: a population-based study","volume":"5","author":"Dai","year":"2019","journal-title":"JACC Clin 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