{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:42:01Z","timestamp":1791319321774,"version":"4.3.1"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T00:00:00Z","timestamp":1742256000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Patients with left ventricular assist devices (LVADs) are at high risk for ventricular tachycardia (VT), and data on VT ablation in patients with LVAD are scarce. This multicentre registry assessed the mechanism of VT, procedural parameters, and outcome of VT ablation in patients with LVAD (NCT06063811).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>Data of patients with LVAD referred for VT ablation at nine tertiary care centres were collected retrospectively. Parameters included VT mechanisms, procedural data, VT recurrence, and mortality. Overall, 69 patients (90% male, mean age 60.7 \u00b1 8.4 years) undergoing 72 ablation procedures were included. Most procedures were conducted after intensification of antiarrhythmic drug (AAD) treatment (18\/72; 25%) or a prior combination of \u22652 AADs (31\/72; 43%). Endocardial low-voltage areas were detected in all patients. The predominant VT mechanism was scar-related re-entry (76\/96 VTs; 79%), and 19\/96 VTs (20%) were related to the LVAD cannula. Non-inducibility of any VT was achieved in 28\/72 procedures (39%). No LVAD-related complication was observed. The extent of endocardial scar was associated with VT recurrence. The median follow-up was 283 days (interquartile range 70\u2013587 days). A total of 3\/69 patients were lost to follow-up, 10\/69 (14%) were transplanted, 26\/69 (38%) died, and 16\/69 (23%) patients were free from VT.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Although often a last resort, VT ablation in patients with LVAD is feasible and safe when performed in experienced centres. These patients suffer from a high scar burden, and cardiomyopathy-associated rather than cannula-related scar seems to be the dominant substrate. Ventricular tachycardia recurrence is high despite extensive treatment, and the overall prognosis is limited.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/europace\/euaf054","type":"journal-article","created":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T19:28:43Z","timestamp":1742326123000},"source":"Crossref","is-referenced-by-count":10,"title":["Characterization of ventricular tachycardia ablation in end-stage heart failure patients with left ventricular assist device (CHANNELED registry)"],"prefix":"10.1093","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0468-4887","authenticated-orcid":false,"given":"Jan-Hendrik","family":"van den Bruck","sequence":"first","affiliation":[{"name":"Department for Electrophysiology, Heart Centre University Hospital of Cologne , Kerpener Strasse 62, Cologne 50937 ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0194-4615","authenticated-orcid":false,"given":"Felix","family":"Hohendanner","sequence":"additional","affiliation":[{"name":"Deutsches Herzzentrum der Charit\u00e9, Klinik f\u00fcr Kardiologie, Angiologie und Intensivmedizin , Berlin ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9782-8311","authenticated-orcid":false,"given":"Emanuel","family":"Heil","sequence":"additional","affiliation":[{"name":"Deutsches Herzzentrum der Charit\u00e9, Klinik f\u00fcr Kardiologie, Angiologie und Intensivmedizin , Berlin ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karolin","family":"Albert","sequence":"additional","affiliation":[{"name":"Hannover Heart Rhythm Centre, Department of Cardiology and Angiology, Hannover Medical School , Hannover ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2996-6338","authenticated-orcid":false,"given":"David","family":"Duncker","sequence":"additional","affiliation":[{"name":"Hannover Heart Rhythm Centre, Department of Cardiology and Angiology, Hannover Medical School , Hannover ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi","family":"Estner","sequence":"additional","affiliation":[{"name":"Department of Medicine I, University Hospital Munich, Ludwig Maximilians University , Munich ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1379-1684","authenticated-orcid":false,"given":"Thomas","family":"Deneke","sequence":"additional","affiliation":[{"name":"University Hospital Klinikum Nuremberg, Clinic for Cardiology and Arrhythmology, Paracelsus Medical University , Nuremberg ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2043-7050","authenticated-orcid":false,"given":"Abdul","family":"Parwani","sequence":"additional","affiliation":[{"name":"Deutsches Herzzentrum der Charit\u00e9, Klinik f\u00fcr Kardiologie, Angiologie und Intensivmedizin , Berlin ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9720-3175","authenticated-orcid":false,"given":"Evgenij","family":"Potapov","sequence":"additional","affiliation":[{"name":"Deutsches Herzzentrum der Charit\u00e9, Klinik f\u00fcr Herz-, Thorax- und Gef\u00e4\u00dfchirurgie , Berlin ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6346-7500","authenticated-orcid":false,"given":"Katharina","family":"Seuthe","sequence":"additional","affiliation":[{"name":"Department for Electrophysiology, Heart Centre University Hospital of Cologne , Kerpener Strasse 62, Cologne 50937 ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2213-8946","authenticated-orcid":false,"given":"Jonas","family":"W\u00f6rmann","sequence":"additional","affiliation":[{"name":"Department for Electrophysiology, Heart Centre University Hospital of Cologne , Kerpener Strasse 62, Cologne 50937 ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1807-4860","authenticated-orcid":false,"given":"Arian","family":"Sultan","sequence":"additional","affiliation":[{"name":"Department for Electrophysiology, Heart Centre University Hospital of Cologne , Kerpener Strasse 62, Cologne 50937 ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0208-3295","authenticated-orcid":false,"given":"Jan-Hendrik","family":"Schipper","sequence":"additional","affiliation":[{"name":"Department for Electrophysiology, Heart Centre University Hospital of Cologne , Kerpener Strasse 62, Cologne 50937 ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3735-8503","authenticated-orcid":false,"given":"Lars","family":"Eckardt","sequence":"additional","affiliation":[{"name":"Department for Cardiology II: Electrophysiology, University Hospital M\u00fcnster , M\u00fcnster ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5237-6283","authenticated-orcid":false,"given":"Florian","family":"Doldi","sequence":"additional","affiliation":[{"name":"Department for Cardiology II: Electrophysiology, University Hospital M\u00fcnster , M\u00fcnster ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3886-0930","authenticated-orcid":false,"given":"Patrick","family":"Lugenbiel","sequence":"additional","affiliation":[{"name":"Heidelberg Centre for Heart Rhythm Disorders, Heidelberg University Hospital , Heidelberg ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2887-8707","authenticated-orcid":false,"given":"Helge","family":"Servatius","sequence":"additional","affiliation":[{"name":"Inselspital, Bern University Hospital, University of Bern , Bern ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregor","family":"Thalmann","sequence":"additional","affiliation":[{"name":"Inselspital, Bern University Hospital, University of Bern , Bern ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7197-8415","authenticated-orcid":false,"given":"Tobias","family":"Reichlin","sequence":"additional","affiliation":[{"name":"Inselspital, Bern University Hospital, University of Bern , Bern ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2454-1335","authenticated-orcid":false,"given":"Moneeb","family":"Khalaph","sequence":"additional","affiliation":[{"name":"Clinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Ruhr-Universit\u00e4t Bochum , Bad Oeynhausen ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1470-7157","authenticated-orcid":false,"given":"Denise","family":"Guckel","sequence":"additional","affiliation":[{"name":"Clinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Ruhr-Universit\u00e4t Bochum , Bad Oeynhausen ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3037-8704","authenticated-orcid":false,"given":"Philipp","family":"Sommer","sequence":"additional","affiliation":[{"name":"Clinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Ruhr-Universit\u00e4t Bochum , Bad Oeynhausen ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6839-5895","authenticated-orcid":false,"given":"Daniel","family":"Steven","sequence":"additional","affiliation":[{"name":"Department for Electrophysiology, Heart Centre University Hospital of Cologne , Kerpener Strasse 62, Cologne 50937 ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4667-2200","authenticated-orcid":false,"given":"Jakob","family":"L\u00fcker","sequence":"additional","affiliation":[{"name":"Department for Electrophysiology, Heart 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