{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T21:00:13Z","timestamp":1793307613619,"version":"4.5.0"},"reference-count":48,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T00:00:00Z","timestamp":1751414400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"French Government as part of the \u2018Investments in the Future\u2019 program managed by the National Research Agency","award":["ANR-10-IAHU-04"],"award-info":[{"award-number":["ANR-10-IAHU-04"]}]},{"name":"Grant France 2030"},{"name":"REFER-RYTHMO network"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The feasibility and safety of the lattice-tip catheter for ventricular arrhythmia (VA) ablation in humans remain largely unknown. This study aimed to assess feasibility, safety profile as well as patient outcomes after VA ablation with a lattice-tip catheter in a multicentre European registry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>All 18 European centres using the AFFERA system in September 2024 agreed to participate. Clinical, procedural, and follow-up data (minimum 3 months) were systematically collected and analysed. A total of 126 patients (18% female; mean age 59 \u00b1 16 years) underwent VA ablation using the lattice-tip catheter during the inclusion period. Ablation indications included ventricular tachycardia (VT) in 99, premature ventricular complexes (PVCs) in 23, and ventricular fibrillation (VF) in 4 patients. Major and minor acute complications were observed in 7 (6%) and 18 (14%) procedures, respectively. They included thrombo-embolic event (n = 2), major bleeding (n = 2), ventricular fibrillation induction (n = 1), tamponade due to epicardial access (n = 1), and cardiogenic shock due to prolonged VT mapping (n = 1). Within the first month post-procedure, three patients died [from multi-organ failure (n = 2) and sepsis (n = 1)], two had worsening heart failure, one myocardial infarction, one sepsis, and one major gastro-intestinal bleeding. After a mean follow-up of 5.6 \u00b1 3.7 months, absence of recurrence was 78% for PVC, 70% for VT, and 100% for VF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this complex population with refractory VA, ablation using the lattice-tip catheter appears feasible and relatively safe. In the absence of large, randomized trials, exhaustive registry is of key importance to ensure safety and efficacy of new catheter technologies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/europace\/euaf139","type":"journal-article","created":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T08:03:54Z","timestamp":1751443434000},"source":"Crossref","is-referenced-by-count":49,"title":["Safety and efficacy of a lattice-tip catheter for ventricular arrhythmia ablation: the AFFERA Ventricular Arrhythmia Ablation Registry (AVAAR)"],"prefix":"10.1093","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8348-9320","authenticated-orcid":false,"given":"Fr\u00e9d\u00e9ric","family":"Sacher","sequence":"first","affiliation":[{"name":"Cardiac Arrhythmia Department, IHU Liryc, Univ. Bordeaux, INSERM 1045, CHU de Bordeaux, CMARY, ERN Guard Heart, REFER-RYTHMO Network , F33600 Bordeaux ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6327-0487","authenticated-orcid":false,"given":"Andrea","family":"Sarkozy","sequence":"additional","affiliation":[{"name":"Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel\u2014Vrije Universiteit Brussel, European Reference Networks Guard-Heart , Brussels ,","place":["Belgium"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8965-8495","authenticated-orcid":false,"given":"Helmut","family":"P\u00fcrerfellner","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Ordensklinikum Linz Elisabethinen , Linz ,","place":["Austria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5466-0118","authenticated-orcid":false,"given":"Alexandra","family":"Steyer","sequence":"additional","affiliation":[{"name":"Cardioangiologische Centrum Bethanien (CCB) , Frankfurt ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0257-8629","authenticated-orcid":false,"given":"Jonathan","family":"Lyne","sequence":"additional","affiliation":[{"name":"Department of Pacing and Electrophysiology, Beacon Hospital , Dublin ,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3494-0707","authenticated-orcid":false,"given":"Charl\u00e8ne","family":"Coquard","sequence":"additional","affiliation":[{"name":"Cardiovascular Institute Paris-Sud (ICPS), Jacques Cartier Private Hospital , Massy ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4093-0483","authenticated-orcid":false,"given":"Romain","family":"Tixier","sequence":"additional","affiliation":[{"name":"Cardiac Arrhythmia Department, IHU Liryc, Univ. Bordeaux, INSERM 1045, CHU de Bordeaux, CMARY, ERN Guard Heart, REFER-RYTHMO Network , F33600 Bordeaux ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Combes","sequence":"additional","affiliation":[{"name":"General and Interventional Cardiology\u2014Rhythmology, Clinic Pasteur , Toulouse ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7644-6146","authenticated-orcid":false,"given":"Michel","family":"Haissaguerre","sequence":"additional","affiliation":[{"name":"Cardiac Arrhythmia Department, IHU Liryc, Univ. Bordeaux, INSERM 1045, CHU de Bordeaux, CMARY, ERN Guard Heart, REFER-RYTHMO Network , F33600 Bordeaux ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michalis","family":"Efremidis","sequence":"additional","affiliation":[{"name":"Department of Electrophysiology and Pacing, Onassis Cardiac Surgery Center , Athens ,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4367-1117","authenticated-orcid":false,"given":"Josselin","family":"Duchateau","sequence":"additional","affiliation":[{"name":"Cardiac Arrhythmia Department, IHU Liryc, Univ. 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