{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T22:32:29Z","timestamp":1792794749297,"version":"4.5.0"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:00:00Z","timestamp":1756425600000},"content-version":"vor","delay-in-days":28,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Prolonged right ventricular pacing (RVP) increases the risk of cardiomyopathy, atrial fibrillation, heart failure (HF), and mortality. This registry-based trial compared left bundle branch area pacing (LBBAP) with RVP in patients younger than 65\u2005years.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>Using the ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing (TREEBEARD) registry (NCT06324682), patients were randomized 1:1 to LBBAP or RVP. The primary endpoint was a composite of cardiovascular (CV) death and HF hospitalization (HFH); secondary endpoints included individual components and all-cause mortality. A total of 344 patients (mean age 58.5\u2005years, 215 males, 172 per arm) were included. At 2\u2005years, the primary composite endpoint occurred in 6.3% of LBBAP vs. 12.7% of RVP patients (HR, 0.78; 95% CI, 0.59\u20130.87), representing a 22% risk reduction. Subgroup analyses aligned with primary findings. Left bundle branch area pacing significantly reduced HFH risk (HR, 0.79; 95% CI, 0.63\u20130.86) but showed no difference in CV mortality (HR, 1.02; 95% CI, 0.79\u20131.32) or all-cause mortality (HR, 1.00; 95% CI, 0.72\u20131.38).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Left bundle branch area pacing significantly lowered the 2-year composite of CV death and HFH compared to RVP in patients aged &amp;lt;65\u2005years old. However, it did not reduce CV or all-cause mortality individually compared to RVP.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Clinical Trial Registration<\/jats:title>\n                  <jats:p>TREEBEARD (NCT06324682)<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/europace\/euaf181","type":"journal-article","created":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T16:16:11Z","timestamp":1756484171000},"source":"Crossref","is-referenced-by-count":27,"title":["Two-year outcomes of left bundle branch area pacing versus traditional right ventricular pacing in middle-aged adults: a registry-based trial"],"prefix":"10.1093","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5285-7140","authenticated-orcid":false,"given":"Matteo","family":"Bertini","sequence":"first","affiliation":[{"name":"Cardiology Unit, Sant\u2019Anna University Hospital, University of Ferrara , Via A. Moro 8, Ferrara Cona (FE) 44124 ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5006-156X","authenticated-orcid":false,"given":"Luca","family":"Canovi","sequence":"additional","affiliation":[{"name":"Cardiology Unit, Sant\u2019Anna University Hospital, University of Ferrara , Via A. Moro 8, Ferrara Cona (FE) 44124 ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0667-7616","authenticated-orcid":false,"given":"Francesco","family":"Vitali","sequence":"additional","affiliation":[{"name":"Cardiology Unit, Sant\u2019Anna University Hospital, University of Ferrara , Via A. Moro 8, Ferrara Cona (FE) 44124 ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5854-9782","authenticated-orcid":false,"given":"Lina","family":"Marcantoni","sequence":"additional","affiliation":[{"name":"Arrhythmia and Electrophysiology Unit, Santa Maria della Misericordia General Hospital , Rovigo ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4040-3838","authenticated-orcid":false,"given":"Gianni","family":"Pastore","sequence":"additional","affiliation":[{"name":"Arrhythmia and Electrophysiology Unit, Santa Maria della Misericordia General Hospital , Rovigo ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5288-0108","authenticated-orcid":false,"given":"Mario","family":"Volpicelli","sequence":"additional","affiliation":[{"name":"Ospedale Santa Maria della Piet\u00e0 Cardiology Unit, , Nola (NA), Napoli ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4073-6595","authenticated-orcid":false,"given":"Orlando","family":"Munciguerra","sequence":"additional","affiliation":[{"name":"Ospedale Santa Maria della Piet\u00e0 Cardiology Unit, , Nola (NA), Napoli ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4590-8584","authenticated-orcid":false,"given":"Mauro","family":"Biffi","sequence":"additional","affiliation":[{"name":"Institute of Cardiology, IRCCS Azienda Ospedaliero Universitaria di Bologna Cardiology Unit, , Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3617-2739","authenticated-orcid":false,"given":"Matteo","family":"Ziacchi","sequence":"additional","affiliation":[{"name":"Institute of Cardiology, IRCCS Azienda Ospedaliero Universitaria di Bologna Cardiology Unit, , Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3288-9134","authenticated-orcid":false,"given":"Luca","family":"Rossi","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Cardiovascular and Emergency, \u2018Guglielmo da Saliceto\u2019 Hospital , Piacenza ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8119-5502","authenticated-orcid":false,"given":"Valeria","family":"Carinci","sequence":"additional","affiliation":[{"name":"Cardiology Unit, Azienda AUSL, Maggiore Hospital , Bologna ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8812-9308","authenticated-orcid":false,"given":"Paolo","family":"Sirugo","sequence":"additional","affiliation":[{"name":"Cardiology Unit, Azienda AUSL, Maggiore Hospital , Bologna ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0459-3056","authenticated-orcid":false,"given":"Paolo","family":"Pastori","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Ospedale Di Fidenza , Fidenza ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3403-3364","authenticated-orcid":false,"given":"Jacopo Francesco","family":"Imberti","sequence":"additional","affiliation":[{"name":"Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena , Modena ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2961-2783","authenticated-orcid":false,"given":"Pier Luigi","family":"Pellegrino","sequence":"additional","affiliation":[{"name":"Cardiology Division, AOU Policlinico Riuniti , Foggia ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7380-0732","authenticated-orcid":false,"given":"Erminia","family":"Guerriero","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences, University of Foggia , Foggia ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9028-7169","authenticated-orcid":false,"given":"Biagio","family":"Sassone","sequence":"additional","affiliation":[{"name":"Division of Provincial Cardiology, Department of Translational Medicine, University of Ferrara , Ferrara ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6335-2597","authenticated-orcid":false,"given":"Enrico","family":"Bertagnin","sequence":"additional","affiliation":[{"name":"Division of Provincial Cardiology, Department of Translational Medicine, University of Ferrara , Ferrara ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3080-407X","authenticated-orcid":false,"given":"Giuseppe","family":"Coppola","sequence":"additional","affiliation":[{"name":"Division of Cardiology, University Hospital \u2018P. Giaccone\u2019, University of Palermo , Palermo ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1972-9665","authenticated-orcid":false,"given":"Michele","family":"Malag\u00f9","sequence":"additional","affiliation":[{"name":"Cardiology Unit, Sant\u2019Anna University Hospital, University of Ferrara , Via A. Moro 8, Ferrara Cona (FE) 44124 ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2110-8961","authenticated-orcid":false,"given":"Cristina","family":"Balla","sequence":"additional","affiliation":[{"name":"Cardiology Unit, Sant\u2019Anna University Hospital, University of Ferrara , Via A. Moro 8, Ferrara Cona (FE) 44124 ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3151-0107","authenticated-orcid":false,"given":"Giorgia","family":"Azzolini","sequence":"additional","affiliation":[{"name":"Cardiology Unit, Sant\u2019Anna University Hospital, University of Ferrara , Via A. Moro 8, Ferrara Cona (FE) 44124 ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria","family":"Zuccari","sequence":"additional","affiliation":[{"name":"Cardiology Unit, Sant\u2019Anna University Hospital, University of Ferrara , Via A. Moro 8, Ferrara Cona (FE) 44124 ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2673-3918","authenticated-orcid":false,"given":"Francesco","family":"Zanon","sequence":"additional","affiliation":[{"name":"Arrhythmia and Electrophysiology Unit, Santa Maria della Misericordia General Hospital , Rovigo ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9820-4815","authenticated-orcid":false,"given":"Giuseppe","family":"Boriani","sequence":"additional","affiliation":[{"name":"Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena , Modena ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4559-1292","authenticated-orcid":false,"given":"Marco","family":"Zuin","sequence":"additional","affiliation":[{"name":"Cardiology Unit, Sant\u2019Anna University Hospital, University of Ferrara , Via A. Moro 8, Ferrara Cona (FE) 44124 ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,8,29]]},"reference":[{"key":"2025082912160914300_euaf181-B1","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1016\/j.jacc.2006.05.072","article-title":"Right ventricular pacing can induce ventricular dyssynchrony in patients with atrial fibrillation after atrioventricular node ablation","volume":"48","author":"Tops","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"2025082912160914300_euaf181-B2","doi-asserted-by":"crossref","first-page":"2932","DOI":"10.1161\/01.CIR.0000072769.17295.B1","article-title":"Adverse effect of ventricular pacing on heart failure and atrial fibrillation among patients with normal baseline QRS duration in a clinical trial of pacemaker therapy for sinus node dysfunction","volume":"107","author":"Sweeney","year":"2003","journal-title":"Circulation"},{"key":"2025082912160914300_euaf181-B3","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1016\/j.hrthm.2014.05.040","article-title":"Incidence and predictors of right ventricular pacing-induced cardiomyopathy","volume":"11","author":"Khurshid","year":"2014","journal-title":"Heart Rhythm"},{"key":"2025082912160914300_euaf181-B4","doi-asserted-by":"crossref","first-page":"3099","DOI":"10.1016\/j.jacc.2017.05.005","article-title":"The continued search for physiological pacing: where are we now?","volume":"69","author":"Vijayaraman","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"2025082912160914300_euaf181-B5","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1093\/europace\/euy252","article-title":"Comparison of electrocardiogram characteristics and pacing parameters between left bundle branch pacing and right ventricular pacing in patients receiving pacemaker therapy","volume":"21","author":"Chen","year":"2019","journal-title":"Europace"},{"key":"2025082912160914300_euaf181-B6","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1016\/j.jacc.2018.02.048","article-title":"Clinical outcomes of his bundle pacing compared to right ventricular pacing","volume":"71","author":"Abdelrahman","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"2025082912160914300_euaf181-B7","doi-asserted-by":"crossref","first-page":"E009261","DOI":"10.1161\/CIRCEP.120.009261","article-title":"Long-term safety and feasibility of left bundle branch pacing in a large single-center study","volume":"14","author":"Su","year":"2021","journal-title":"Circ Arrhythm Electrophysiol"},{"issue":"3","key":"2025082912160914300_euaf181-B8","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1016\/j.hrthm.2024.08.052","article-title":"Conduction system pacing associated with reduced heart failure hospitalizations and all-cause mortality compared with traditional right ventricular pacing in the Medicare population","volume":"22","author":"Vijayaraman","year":"2025","journal-title":"Heart Rhythm"},{"key":"2025082912160914300_euaf181-B9","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1111\/j.1540-8159.2007.00646.x","article-title":"Ventricular pacing threshold variations in the young","volume":"30","author":"Silvetti","year":"2007","journal-title":"Pacing Clin Electrophysiol"},{"key":"2025082912160914300_euaf181-B10","doi-asserted-by":"crossref","first-page":"e003564","DOI":"10.1161\/CIRCOUTCOMES.117.003564","article-title":"Incidence and time course for developing heart failure with high-burden right ventricular pacing","volume":"10","author":"Merchant","year":"2017","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"2025082912160914300_euaf181-B11","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1056\/NEJMoa1706443","article-title":"Bivalirudin versus heparin monotherapy in myocardial infarction","volume":"377","author":"Erlinge","year":"2017","journal-title":"N Engl J Med"},{"key":"2025082912160914300_euaf181-B12","doi-asserted-by":"crossref","first-page":"e068057","DOI":"10.1136\/bmjopen-2022-068057","article-title":"Registry randomised trials: a methodological perspective","volume":"13","author":"Doherty","year":"2023","journal-title":"BMJ Open"},{"key":"2025082912160914300_euaf181-B13","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1038\/nrcardio.2015.33","article-title":"Registry-based randomized clinical trials\u2014a new clinical trial paradigm","volume":"12","author":"James","year":"2015","journal-title":"Nat Rev Cardiol"},{"key":"2025082912160914300_euaf181-B14","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jclinepi.2016.08.003","article-title":"Registry-based randomized controlled trials\u2014what are the advantages, challenges, and areas for future research?","volume":"80","author":"Li","year":"2016","journal-title":"J Clin Epidemiol"},{"key":"2025082912160914300_euaf181-B15","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1056\/NEJMp1310102","article-title":"The randomized registry trial\u2014the next disruptive technology in clinical research?","volume":"369","author":"Lauer","year":"2013","journal-title":"N Engl J Med"},{"key":"2025082912160914300_euaf181-B16","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1016\/j.jacep.2021.04.005","article-title":"Left bundle branch pacing optimized cardiac resynchronization therapy: a novel approach","volume":"7","author":"Vijayaraman","year":"2021","journal-title":"JACC Clin Electrophysiol"},{"key":"2025082912160914300_euaf181-B17","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1093\/europace\/euad043","article-title":"EHRA clinical consensus statement on conduction system pacing implantation: endorsed by the Asia Pacific Heart Rhythm Society (APHRS), Canadian Heart Rhythm Society (CHRS), and Latin American Heart Rhythm Society (LAHRS)","volume":"25","author":"Burri","year":"2023","journal-title":"Europace"},{"key":"2025082912160914300_euaf181-B18","doi-asserted-by":"crossref","first-page":"euad168","DOI":"10.1093\/europace\/euad168","article-title":"The evolving state of cardiac resynchronization therapy and conduction system pacing: 25 years of research at EP europace journal","volume":"25","author":"Ellenbogen","year":"2023","journal-title":"Europace"},{"key":"2025082912160914300_euaf181-B19","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1093\/europace\/euac201","article-title":"Conduction system pacing in everyday clinical practice: EHRA physician survey","volume":"25","author":"Kircanski","year":"2023","journal-title":"Europace"},{"key":"2025082912160914300_euaf181-B20","doi-asserted-by":"crossref","first-page":"euad019","DOI":"10.1093\/europace\/euad019","article-title":"Conduction system pacing, a European survey: insights from clinical practice","volume":"19","author":"Keene","year":"2023","journal-title":"Europace"},{"key":"2025082912160914300_euaf181-B21","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1093\/europace\/euac245","article-title":"Comparison of methods for delivering cardiac resynchronization therapy: an acute electrical and haemodynamic within-patient comparison of left bundle branch area, His bundle, and biventricular pacing","volume":"25","author":"Ali","year":"2023","journal-title":"Europace"},{"key":"2025082912160914300_euaf181-B22","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.hrthm.2021.08.033","article-title":"Clinical outcomes of left bundle branch area pacing compared to right ventricular pacing: results from the Geisinger-Rush Conduction System Pacing Registry","volume":"19","author":"Sharma","year":"2022","journal-title":"Heart Rhythm"},{"key":"2025082912160914300_euaf181-B23","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1056\/NEJMoa1308789","article-title":"Thrombus aspiration during ST-segment elevation myocardial infarction","volume":"369","author":"Fr\u00f6bert","year":"2013","journal-title":"N Engl J Med"},{"key":"2025082912160914300_euaf181-B24","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/j.hrthm.2005.05.015","article-title":"Percent right ventricular pacing predicts outcomes in the DAVID trial","volume":"2","author":"Sharma","year":"2005","journal-title":"Heart Rhythm"},{"key":"2025082912160914300_euaf181-B25","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1056\/NEJMoa1210356","article-title":"Biventricular pacing for atrioventricular block and systolic dysfunction","volume":"368","author":"Curtis","year":"2013","journal-title":"N Engl J Med"},{"key":"2025082912160914300_euaf181-B26","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1161\/CIRCULATIONAHA.120.047065","article-title":"Trends in recurrent coronary heart disease after myocardial infarction among US women and men between 2008 and 2017","volume":"143","author":"Peters","year":"2021","journal-title":"Circulation"},{"key":"2025082912160914300_euaf181-B27","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1093\/europace\/euw364","article-title":"Single lead atrial vs. dual chamber pacing in sick sinus syndrome: extended register-based follow-up in the DANPACE trial","volume":"19","author":"Brandt","year":"2017","journal-title":"Europace"},{"key":"2025082912160914300_euaf181-B28","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1002\/clc.4960160710","article-title":"Anatomy, histology, and pathology of the cardiac conduction system--Part V","volume":"16","author":"Waller","year":"1993","journal-title":"Clin Cardiol"},{"key":"2025082912160914300_euaf181-B29","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1161\/01.CIR.88.3.915","article-title":"Slow conduction in the infarcted human heart. \u2018Zigzag\u2019 course of activation","volume":"88","author":"de Bakker","year":"1993","journal-title":"Circulation"},{"key":"2025082912160914300_euaf181-B30","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.jacc.2010.12.045","article-title":"Syncope due to idiopathic paroxysmal atrioventricular block: long-term follow-up of a distinct form of atrioventricular block","volume":"58","author":"Brignole","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"2025082912160914300_euaf181-B31","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jclinepi.2016.08.003","article-title":"Egistry-based randomized controlled trials- what are the advantages, challenges, and areas for future research?","volume":"80","author":"Li","year":"2016","journal-title":"J Clin Epidemiol"},{"key":"2025082912160914300_euaf181-B32","doi-asserted-by":"publisher","first-page":"S2405","DOI":"10.1016\/j.jacep.2025.03.037","article-title":"Left ventricular mechanical insights into left bundle branch pacing and left ventricular septal pacing","author":"Bertini","year":"2025","journal-title":"JACC Clin Electrophysiol"}],"container-title":["Europace"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/europace\/article-pdf\/27\/8\/euaf181\/64149559\/euaf181.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/europace\/article-pdf\/27\/8\/euaf181\/64149559\/euaf181.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T16:16:15Z","timestamp":1756484175000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/europace\/article\/doi\/10.1093\/europace\/euaf181\/8242754"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":32,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8,4]]}},"URL":"https:\/\/doi.org\/10.1093\/europace\/euaf181","relation":{},"ISSN":["1099-5129","1532-2092"],"issn-type":[{"value":"1099-5129","type":"print"},{"value":"1532-2092","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,8]]},"published":{"date-parts":[[2025,8]]},"article-number":"euaf181"}}